Tag: colon

Hydrogen peroxide keeps gut bacteria away from the colon lining

Scientists at UC Davis Health have discovered that an enzyme in the colon lining releases hydrogen peroxide (H2O2) – a known disinfecting compound- to protect the body from gut microbes. Their study, published Dec. 9 in the journal Cell Host and Microbe, sheds light on the way microorganisms are spatially organized in the colon. It

Metabolic adaptation ensures survival of colon cancer cells

Colon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to adapt to the lack of oxygen and nutrients inside the tumor. Statins, which are often prescribed to lower cholesterol, block this metabolic pathway and cause the cancer cells to die, as scientists from

Genetically manipulating protein level in colon cancer cells can improve chemotherapy

Colorectal cancer outcomes may improve by genetically altering an immune-regulatory protein in cancer cells, making the cells more vulnerable to chemotherapy. That’s according to new Mayo Clinic research. The findings, published this month in Oncogene, indicate that increasing the expression of the PD-L1 protein in colorectal cancer cells can improve the effectiveness of chemotherapy. “These

Choose the right colon cancer screening option

(HealthDay)—Colon cancer is highly preventable through regular screening. But the right type of screening depends on your particular risk factors, an expert says. Each year in the United States, more than 140,000 people are diagnosed with colon cancer, and about 50,000 die from the disease. It’s the second-leading cause of cancer death in the country.

How a common oral bacteria makes colon cancer more deadly

Researchers at the Columbia University College of Dental Medicine have determined how F. nucleatum—a common oral bacteria often implicated in tooth decay—accelerates the growth of colon cancer. The study was published online in the journal EMBO Reports. The findings could make it easier to identify and treat more aggressive colon cancers. It also helps explain

Better understanding of how colon cancer develops and progresses

Researchers from the University of Luxembourg have discovered a molecular mechanism that is responsible for the spread of cancer cells in the body and the development of metastases in patients with colon cancer. Their findings could help to develop treatments that inhibit tumor growth. Colorectal cancer (CRC) is among the most prevalent cancer types worldwide,

To Boost Colon Cancer Screening, Use the Mail

TUESDAY, July 31, 2018 — Colon cancer is treatable if caught early. And sending screening tests in the mail might boost timely detection, a new study suggests. University of North Carolina (UNC) researchers found that Medicaid patients were more likely to get screened if they received stool-testing kits by mail instead of just reminders. “There