Tag: compound

In a new paper published by Nature Communications, The Lundquist Institute (TLI) Investigator Wei Yan, MD, Ph.D., and his research colleagues spell out an innovative strategy that has led to the discovery of a natural compound as a safe, effective and reversible male contraceptive agent in pre-clinical animal models. Despite tremendous efforts over the past

Gas chromatography-mass spectrometry (GC-MS) is a tool that is used to separate, quantify, and analyze organic compounds that are naturally volatile. This article describes how to interpret and present GC-MS results in a publication, for all purposes. HPLC chromatogram of common food additives. Chromatos | Shutterstock. Understanding GC-MS Gas chromatography is used to separate the

Indiana University researchers have discovered that a chemical compound found in essential oils improves the healing process in mice when it is topically applied to a skin wound—a finding that could lead to improved treatments for skin injuries in humans. IU scientists also reported that skin tissue treated with the chemical compound, beta-carophyllene—which is found

Children with autism often find social interactions awkward, leaving them isolated. Now in a study appearing in ACS’ Journal of Medicinal Chemistry, scientists report that they have discovered a first-of-its-kind compound that promotes social interaction among laboratory mice that display autistic traits. The finding could lead to the development of drugs capable of improving social

Antiretroviral therapies have worked wonders suppressing HIV replication and its progression to AIDS, but their effectiveness is deteriorating due to the constant development of drug resistance in the virus. Now Yale researchers have shown their newly developed compounds maintain anti-HIV activity against drug-resistant mutants better than FDA-approved medications. The new compounds work by inhibiting the

Being aware of our surroundings is a fundamental aspect of our existence. But what in our biological makeup determines how we access and interpret the endless stream of information around us? A new Tel Aviv University study published in Current Biology suggests that noradrenaline, a neurotransmitter responsible for arousal in the brain, plays a vital

Fighting cancer means killing cancer cells. However, oncologists know that it’s also important to halt the movement of cancer cells before they spread throughout the body. New research, published today in the journal Nature Communications, shows that it may be possible to freeze cancer cells and kill them where they stand. Raymond Bergan, M.D., Division

The newest antiviral drugs could take advantage of a compound made not by humans, but inside them. A team of researchers has identified the mode of action of viperin, a naturally occurring enzyme in humans and other mammals that is known to have antiviral effects on a wide variety of viruses, including West Nile, hepatitis

Purdue University researchers have identified  a new compound that in preliminary testing has shown itself to be as effective as antibiotics approved by the Food and Drug Administration to treat life-threatening infections while also appearing to be less susceptible to bacterial resistance. The compound, called F6, has been potent against antibiotic-resistant pathogens such as methicillin-resistant

A team of Russian scientists together with foreign colleagues, reports that the venom of the crab spider Heriaeus melloteei may be used as a basis for a treatment against hypokalemic periodic paralysis. This disease is caused by genetic mutation that leads to the occurrence of the so-called ω-currents, or leakage currents, via voltage-gated ion channels