Tag: Coronavirus Disease COVID-19

Elderly residents of long-term care facilities benefit from booster vaccines against SARS-CoV-2

Older age is a strong risk factor for severe coronavirus disease 2019 (COVID-19) compared to children and younger adults with COVID-19. In addition, older adults infected by SARS-CoV-2 are rarely asymptomatic and experience severe symptoms such as respiratory failure and multi-organ dysfunction that can lead to hospitalization and/or death. Therefore, older adults have been granted

Chronological changes in SARS-CoV-2 immune responses after BNT162b2 vaccine

Rapid transmission of a novel coronavirus, namely, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in the coronavirus disease 2019 (COVID-19) pandemic. This pandemic has massively affected the world’s economy and the healthcare system. In response to the pandemic, scientists and healthcare officials developed various pharmaceutical and non-pharmaceutical measures. Study: SARS-CoV-2 specific T cell

BNT162b2 mRNA COVID-19 vaccine effectiveness amongst Italian healthcare workers

The ongoing coronavirus disease 2019 (COVID-19) pandemic has been caused by the rapid outbreak of the severe acute respiratory coronavirus 2 (SARS-CoV-2). Scientists have developed novel vaccines, and vaccination programs have commenced in many countries. In Italy, the program started in December 2020, and the available vaccine was the BNT162b2 mRNA vaccine (Cominarty). Study: BNT162b2

Study finds immunity against SARS-CoV-2 delta variant waned after BNT162b2 vaccine second dose

Variants of concern of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have shown the ability to avoid vaccine-induced and natural immunity. The Delta variant is now responsible for over 90% of new cases. In a study published in the New England Journal of Medicine, researchers from Israel have investigated the possibility that vaccine-induced immunity reduces

COVID-19 vaccination side effects in the USA

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has hugely impacted human health and the economy worldwide. Researchers and healthcare professionals believed that the impact of COVID-19 could only be reduced by the administration of vaccines. Study: How frequent are acute reactions to COVID-19 vaccination and who is

Dispensing of hydroxychloroquine and ivermectin in Australia jumped in first year of COVID

Australia adopted a quick and stern response to the coronavirus disease 2019 (COVID-19) pandemic by closing international borders, as well as locking down localities and regions for varying periods of time to stop the transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) across the country. However, common beliefs fueled by celebrity endorsements caused

Study reveals why SARS-CoV-2 is more infectious than SARS-CoV-1

Coronaviruses such as the severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 are enveloped positive-sense RNA viruses that are a huge threat to public health globally. They can be transmitted from animals to humans and can cause many diseases ranging from the common cold to severe respiratory illnesses. Study: The supramolecular organization of SARS-CoV and

Pinning down Pin1: Potential COVID-19 therapy

In their recent study published in Nature Scientific Reports, scientists from Japan have demonstrated that Prolyl isomerase Pin1 is one of the key cellular molecules necessary for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) propagation. Study: Prolyl isomerase Pin1 plays an essential role in SARS-CoV-2 proliferation, indicating its possibility as a novel therapeutic target. Image

Humoral and cellular response to COVID-19 vaccines in patients with IBD

Researchers worldwide hypothesized that the development of vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could help to reduce transmission and help to lower the mortality rate. The vaccines developed against coronavirus disease 2019 (COVID-19) had to undergo several clinical trials before they could be considered safe for human use. Patients of various age

MinoTour: a real-time monitoring platform to analyze SARS-CoV-2 nanopore sequencing

The coronavirus disease 2019 (COVID-19) pandemic is caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). This pandemic has indicated the effectiveness of real-time analysis of sequencing data linked to a wide range of databases. Study: Real-time monitoring and analysis of SARS-CoV-2 nanopore sequencing with minoTour. Image Credit: Design_Cells/ Shutterstock Scientists have proposed that real-time

Rosin soap as a potential SARS-CoV-2 disinfectant

Rosin is a solid resin obtained from pine trees used for various applications, including as soap. Rosin contains numerous lipid-soluble acids and has previously demonstrated antibacterial activity against Gram-positive bacteria, in particular, acting by disruption of the cell membrane. In a research paper recently uploaded to the preprint server bioRxiv* by Bell et al. (July

Study reports low risk for COVID-19 in Emergency Medical Service personnel exposed to aerosol-generating procedures

Amid the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), healthcare providers working on the frontlines are a particularly high-risk group for infection. Though vaccination efforts prioritized this group, working directly with COVID-19 patients makes them at risk of contracting the virus. The U.S. Centers for Disease Control

SARS-CoV N protein elicits production of IFN-β by provoking ubiquitination of RIG-I, finds study

Many members of the Coronaviridae family such as the middle east respiratory syndrome (MERS), severe acute respiratory syndrome (SARS), and the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are known to be threats to public health. However, among all coronaviruses (CoVs), SARS-CoV-2, which is the causal agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic,