A person’s chance of developing dementia is influenced by family history, variations in certain genes, and medical conditions such as cardiovascular disease and diabetes. But less is known about the factors that affect when the first symptoms of forgetfulness and confusion will arise. A new study from Washington University School of Medicine in St. Louis
Hormone therapy for prostate cancer increases risk of DEMENTIA by 20%, study finds The large study in the US looked at nearly 155,000 men with an average age of 74 It found those given the therapy had a 20% increased risk of any type of dementia A hormone therapy used to treat prostate cancer in men
The research also demonstrated that statin users had a 23 per cent reduction in the risk of stroke, which is three times more likely in patients with mild dementia and seven times more likely in those with severe dementia. The use of statins is significantly associated with a reduction in the risk of mortality in
A common genetic deficiency empowers glioblastoma to broadcast a molecular message to the wrong type of immune cell, summoning macrophages that protect and nurture the brain tumor instead of attacking it, researchers at The University of Texas MD Anderson Cancer Center report in Cancer Cell. The team’s work in mouse models of glioblastoma that lack
As dementia advances, in most cases it can change the behaviour displayed by those with the condition. Such changes in behaviour can bring strain to a wide-ranging network of relationships—from those between people with dementia and their professional carers, between those with dementia and their families, and to relationships between residents in residential care homes—which
Various clinical trials indicate what effects can be expected from standardized intervention programs on the basis of existing evidence. Little is known about the way in which such programs can be implemented in actual care practice. However, it may be possible to use data from clinical practice to estimate the potential of drug prescriptions to
Antibiotics prescribed by dentists as a preemptive strike against infection are unnecessary 81% of the time, according to a study published today in JAMA Network Open. The findings are important because dentists are responsible for 10% of all antibiotic prescriptions written in the United States. Antibiotics prescribed when not warranted expose patients to the risk
Researchers at the Fralin Biomedical Research Institute at Virginia Tech Carilion have revealed how a genetic message to produce healthy heart tissue is altered in the body during stress and aging to contribute to sudden cardiac death. The discovery published in today’s (Tuesday, May 28) Cell Reports centers on communication between heart cells and allows
Dysfunctional neurons in the hippocampus of adult female mice modeling dementia can be repaired and reconnected to distant parts of the brain, reports a new study published in JNeurosci. The similarity between the mouse model and the human condition underscores the therapeutic potential of targeting these cells in dementia patients. The hippocampus generates new brain
Dementia is the name given to a group of symptoms linked to an ongoing decline in brain function, according to the NHS. There are a number of different types of dementia, but the most common is Alzheimer’s disease. Alzheimer’s is believed to be caused by an abnormal build-up of proteins in and around the brain. You could be
Many Americans in their 50s and early 60s are worried about declining brain health, especially if they have loved ones with memory loss and dementia, a new national poll finds. But while the majority of those polled say they take supplements or do puzzles in an effort to stave off brain decline, very few of
Researchers at UC Davis and UC San Francisco have found a way to teach a computer to precisely detect one of the hallmarks of Alzheimer’s disease in human brain tissue, delivering a proof of concept for a machine-learning approach to distinguishing critical markers of the disease. Amyloid plaques are clumps of protein fragments in the
A brain disorder that mimics symptoms of Alzheimer’s disease has been defined with recommended diagnostic criteria and guidelines for advancing future research on the condition. Researchers at Rush University Medical Center and scientists from several National Institutes of Health-funded institutions, in collaboration with international peers, described the newly-named pathway to dementia, Limbic-predominant Age-related TDP-43 Encephalopathy,
A team of scientists at NeuroElectronics Research Flanders (NERF- empowered by imec, KU Leuven and VIB) found that highly demanding and rewarding experiences result in stronger memories. By studying navigation in rats, the researchers traced back the mechanism behind this selective memory enhancement to so-called replay processes in the hippocampus, the memory-processing center of the
Treatments that prevent recurrence of types of stroke and dementia caused by damage to small blood vessels in the brain have moved a step closer, following a small study. The drugs—called cilostazol and isosorbide mononitrate—are already used to treat other conditions, such as heart disease and angina. This is the first time they have been
Worldwide, 50 million people are living with Alzheimer’s disease and other dementias. According to the Alzheimer’s Association, every 65 seconds someone in the United States develops this disease, which causes problems with memory, thinking and behavior. It has been more than 100 years since Alois Alzheimer, M.D., a German psychiatrist and neuropathologist, first reported the
Young people with cognitive impairments and developmental disabilities, including Down syndrome, have similar weight-loss trajectories to those with typical cognitive function after bariatric surgery, according to a new study in Pediatrics authored by psychologists at Children’s National Health System. The study is the first to look at post-surgical outcomes for this subgroup of adolescent bariatric
St. Jude Children’s Research Hospital scientists have cracked the mystery surrounding the most common genetic cause of amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease. The research suggests possible new approaches to diagnosis and treatment of the lethal disorder. The findings appear online today in the journal Molecular Cell. About 35 percent of ALS cases
Dementia-stricken husband who does not speak holds his 74-year-old wife’s hand while listening to their love song as she credits a ‘music memory box’ for helping his remember their lives The box filled with memorabilia plays songs for the person with dementia Steve Garrity, 82, was diagnosed with dementia and Parkinson’s in 2011 Monica Garrity
Increased risk for dementia due to the late beginning of the period? Researchers found now that the time of the occurrence of the period and the menopause may indicate to women at increased risk for dementia. If in the case of women, the period starts late or come in early in the menopause, is associated
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