A new computational analysis suggests that, beyond the initial effect of one infected person arriving and spreading disease to a previously uninfected population, the continuous arrival of more infected individuals has a significant influence on the evolution and severity of the local outbreak. Mattia Mazzoli, Jose Javier Ramasco, and colleagues present these findings in the
If you have heart disease or risk factors for heart disease, you already know about the increased risk of heart attack and stroke. But did you know that coming down with the flu can substantially increase the risk of a serious or even fatal cardiac event? Or that getting the influenza vaccine can substantially reduce
Lyme disease has become an insidious epidemic in the United States. Caused by bacteria transmitted through the bite of an infected tick, it can lead to heart problems, meningitis or arthritis if left untreated. It is the most common tick-borne illness in the United States, and the Centers for Disease Control and Prevention estimates that
We’re living longer, but not necessarily better. As the population over 65 in the United States is projected to double by 2060—with one in five residents in retirement age—so will the number of Americans needing long-term care services. A new study suggests targeting aging itself—rather than individual diseases associated with it—could be the secret to
KUALA LUMPUR, Malaysia — When Mohamad Nor Abdullah put a white flag outside his window late at night, he didn’t expect the swift outpouring of support. By morning, dozens of strangers knocked on his door, offering food, cash and encouragement. Malaysia’s nationwide lockdown to curb a coronavirus surge was tightened further on Saturday, banning people
BANGKOK — Faced with a sharp rise in coronavirus cases, the Thai capital on Sunday announced a ban on indoor dining and gatherings of more than 20 people, in addition to the closure of construction sites and the sealing off of workers’ quarters in Bangkok and nine other provinces. The measures will remain for 30
(HealthDay)—The incidence of hypertension is 12 times higher in children with surgical repair of congenital heart disease (CHD) versus healthy, matched children without CHD, according to a study published online April 8 in JAMA Network Open. Jason H. Greenberg, M.D., from the Yale University School of Medicine in New Haven, Connecticut, and colleagues used Canadian
Researchers in the Department of Neurology at Tohoku University, which is led by professor Masashi Aoki, have developed a classification scheme for neuromyelitis optica spectrum disorder, a rare autoimmune disease that until recently was thought to be a type of multiple sclerosis (MS). The new taxonomy for the disease replaces one borrowed from MS but
Primary sclerosing cholangitis (PSC) is a rare chronic inflammatory disease of the bile ducts and is difficult to treat, since its causes have not yet been adequately researched. Using RNA sequencing, an international research consortium led by Michael Trauner, Head of MedUni Vienna’s Division of Gastroenterology and Hepatology (Department of Medicine III), has now identified
The development of a wearable to detect early Alzheimer’s and other neurodegenerative diseases years before symptoms show has taken a step closer to reality today, as UK charity Alzheimer’s Research UK announces a partnership with Boston University that will see the first digital data flowing into its global Early Detection of Neurodegenerative diseases (EDoN) initiative.
A newly developed smartphone app may help patients with chronic kidney disease keep up to date on their medications and accurately follow their prescriptions to safeguard their health. The app was tested in a study that will appear in an upcoming issue of CJASN. For individuals with chronic conditions, not taking their prescribed medications properly
Researchers from the Mitochondrial Medicine Frontier Program at Children’s Hospital of Philadelphia (CHOP) have demonstrated how one combination of therapies may be beneficial for patients with mitochondrial respiratory chain disorders. This preclinical research paves the way to develop more tailored treatment options for patients with inherited mitochondrial disease and acquired energy disorders. The findings emphasize
Scientists are still a long way from being able to treat Alzheimer’s Disease, in part because the protein aggregates that can become brain plaques, a hallmark of the disease, are hard to study. The plaques are caused by the amyloid beta protein, which gets misshapen and tangled in the brain. To study these protein aggregates
Female physicians have better patient outcomes compared with their male peers, while female patients are less likely to receive guideline-recommended care when treated by a male physician, according to a systematic review from the American College of Cardiology’s Cardiovascular Disease in Women section published today in the Journal of the American College of Cardiology. While
A team of neuroscientists has identified a potential means to address the loss of cognitive function due to Alzheimer’s disease by targeting protein synthesis in mice. Their findings, reported in the journal Science Signaling, reveal that synthetic pharmaceuticals could rescue the activity of brain cells needed for memory formation. “This work is the first to
A World Health Organization team investigating the origins of the coronavirus pandemic has visited a provincial disease control center that had an early hand in managing the outbreak. The WHO investigators arrived in the Hubei provincial capital, Wuhan, last month to look for clues and have visited hospitals that treated many of the earliest patients
(HealthDay)—Current and former smokers are at risk for a lung disease called pulmonary fibrosis, but many aren’t aware of the threat, the Pulmonary Fibrosis Foundation says. There is no cure for the disease, which affects more than 200,000 Americans. A recent foundation survey found that more than 80% of smokers are unfamiliar with pulmonary fibrosis.
Another day, another announcement about a COVID-19 vaccine. Whether that’s talk of results from clinical trials, emergency approval or plans for countries to prioritize certain groups for vaccination. But we still don’t know if current vaccines prevent disease and also prevent people transmitting the virus to others. This not only has implications for vaccines we’ve
Recently, a research team led by Profs. Liu Qingsong and Liu Jing from the Institute of Health & Medical Technology of the Hefei Institutes of Physical Science (HFIPS) discovered a potent and selective PI3Kδ inhibitor IHMT-PI3Kδ-372, effective against chronic obstructive pulmonary disease (COPD) in vivo. COPD is a chronic progressive respiratory disease characterized by airflow
A form of artificial intelligence designed to interpret a combination of retinal images was able to successfully identify a group of patients who were known to have Alzheimer’s disease, suggesting the approach could one day be used as a predictive tool, according to an interdisciplinary study from Duke University. The novel computer software looks at
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