A clinical trial has begun which will use stem cell transplants to grow a new immune system for people with untreatable Crohn’s disease—a painful and chronic intestinal disease which affects at least 115,000 people in the UK. The study, led by Queen Mary University of London and Barts Health NHS trust, is funded with £2m
Keratinocyte skin cells are common targets of the beta subtype of human papilloma virus. This usually harmless infection causes skin disease in people with rare gene mutations.[/caption] You’re probably infected with one or more subtypes of the human papilloma virus—and, as alarming as that may sound, odds are you will never show any symptoms. The
Hand, foot and mouth disease is in the news with Yankees pitcher J.A. Happ becoming the second Major League Baseball pitcher afflicted in recent weeks. Mets pitcher Noah Syndergaard was the first player to get felled by the ailment, reportedly after visiting a children’s camp. But doctors say it’s vital to understand that the group
Almost two-thirds of non-diabetic patients with Parkinson’s disease (PD) may be insulin resistant, despite having normal blood sugar, report scientists in the Journal of Parkinson’s Disease. Their findings suggest that insulin resistance in PD is a common and largely undetected problem, especially in patients who are overweight. Reduced glucose tolerance has long been recognized as
A new study published in Molecular Genetics and Metabolism, conducted by a Liverpool based research collaboration involving the University of Liverpool, has identified the drug that treats the extremely rare genetic disease alkaptonuria (AKU). An observational study at the NHS-funded Robert Gregory National Alkaptonuria Centre (NAC), based at the Royal Liverpool University Hospital, in collaboration
Experimental Alzheimer’s drug raises hopes after it appears to slow down effects of the degenerative disease for more than 100 trial patients On cognitive tests, patients who received the highest dose of the drug performed 30 percent better At the beginning of the study, all the participants had signs of plaques in the brain that
Short- and long-term depressive symptoms can predict the occurrence of cardiovascular events, according to a new study by University of Maine researchers. In addition, short-term or baseline depressive symptoms increase risk for cardiovascular events for up to 15 years, and chronic depressive symptoms for up to 10 years. The study by the UMaine research team—Emily
For a long time, I thought getting shingles was something that could only happen to you once you reached the age of 60 or older. But after a friend of mine had it in his 30s and was in quite a bit of pain, I realized it’s not a virus only older people can get.
An analysis of recent high-quality research reveals that diet may affect individuals’ risks related to the development and progression of age-related macular degeneration (AMD). The findings are published in Clinical & Experimental Ophthalmology. The systematic review included the analysis of 18 high-quality studies. Adherence to a Mediterranean diet was linked with a decreased risk of
Breathing in additional oxygen improves the function of blood vessels in the brain of people with breathing difficulties caused by lung conditions, according to new research published in Experimental Physiology. These findings could have implications for future research aiming to prevent the development of diseases affecting the brain, such as dementia. Chronic obstructive pulmonary disease
Scientists in Dresden, Germany, have been successful in mimicking mechanisms of Alzheimer’s disease in a novel, stem cell-based model system that reproduces features of human brain tissue. This experimental tool can be used to study mechanisms of pathology and help to find new therapeutic approaches, the researchers say. Their results, published in the journal Developmental
Parkinson’s can affect anyone, especially in later years. Males are more likely to get the disease, but it’s important for both aging males and females to know the signs. The following symptoms could signal Parkinson’s disease. Be sure to get checked out if you have one common irritable symptom (page 9). 1. You notice a
Chemical compounds produced by the bacteria in our gut could be used to spot the early stages of liver disease, according to new research. The findings, published in the journal Nature Medicine, hint at the potential for chemical by-products produced by the microbes living inside us to be used as early warning signs of disease,
HALF of top athletes claim their high-carb diets are rotting their teeth and holding them back from gold medals! Winning athletes love to bite their gold medals and smile for the TV cameras However, their teeth may actually be holding them back, according to a study The study looked at 350 athletes from nine Great
In a study of children with chronic kidney disease (CKD), blood pressure medications reduced protein excretion in the urine, which was linked with a lower risk of disease progression. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN), provide valuable information for monitoring and treating pediatric
Bisexual men have a higher risk for heart disease compared with heterosexual men across several modifiable risk factors, finds a new study published online in the journal LGBT Health. “Our findings highlight the impact of sexual orientation, specifically sexual identity, on the cardiovascular health of men and suggest clinicians and public health practitioners should develop
Of the major illnesses facing humanity, Alzheimer’s disease (AD) remains among the most pitiless and confounding. Over a century after its discovery, no effective prevention or treatment exists for this progressive deterioration of brain tissue, memory and identity. With more people living to older ages, there is a growing need to clarify Alzheimer’s disease risk
A first-ever tissue implant to safely treat a common jaw defect, known as temporomandibular joint dysfunction, has been successfully tested by UCI-led researchers in a large animal model, according to new findings. “We were able to show that we could achieve exceptional healing of the TMJ area after eight weeks of treatment,” said UCI distinguished
The average 10-year risk of developing cardiovascular disease varies widely among India’s states, ranging from 13.2% to 19.5%, with substantial variation across socio-demographic groups according to a study published this week in PLOS Medicine by Pascal Geldsetzer and Rifat Atun of Harvard University, and colleagues. Cardiovascular disease (CVD) is the leading cause of mortality in
Reviewing medical information gathered on more than 6,000 adults over a 10-year period, Johns Hopkins researchers have found that lower than normal blood levels of vitamin D were linked to increased risk of early signs of interstitial lung disease (ILD). Interstitial lung disease is a relatively rare group of disorders characterized by lung scarring and
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