Tag: Diseases and Conditions

A team of researchers under the direction of the Medical Center — University of Freiburg has succeeded in demonstrating in an animal model that previously entirely unknown types of immune cells are present in the inflamed brain in the course of multiple sclerosis (MS). The discovery was made by means of a new, high-resolution method

A comprehensive package of prevention, screening, and treatment interventions could avert 15.1 million new hepatitis C infections and 1.5 million cirrhosis and liver cancer deaths globally by 2030 — equal to an 80% reduction in incidence and a 60% reduction in deaths compared with 2015, according to the first study to model hepatitis C interventions

If hospital doctors around the world often struggle to become those health centaurs, half professionals and half managers, that modern healthcare organizations need, the main responsibility is not their resistance to change, but the lack of effective support from the organization, according to a study by Marco Sartirana (CERGAS, Bocconi University), Graeme Currie (Warwick Business

A study by researchers at Vanderbilt University Medical Center has strengthened the link between thyroid function and atrial fibrillation (AF), an irregular heart rhythm that increases the risk of stroke and other heart-related complications. The phenome-wide association study scanned the medical records of more than 37,000 people for an association between genetically determined variation in

The complex sugars found in human breastmilk, long believed to be fixed in their composition, may change in women who are taking probiotics, according to new research from the University of Rochester Medical Center (URMC). The finding, published in a research letter in JAMA Pediatrics, upends what scientists thought of human milk oligosaccharides (HMOs) —

Bringing a long quest to a satisfying conclusion, researchers have mapped the active-state structure of the angiotensin II type 1 receptor, the target of widely prescribed drugs to regulate blood pressure and kidney function. The study, published online Jan. 10 in Cell, was conducted by researchers in the Blavatnik Institute at Harvard Medical School and

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered that squamous cell skin cancers do not require increased glucose to power their development and growth, contrary to a long-held belief about cancer metabolism. The findings could bring about a better understanding of many cancers’ metabolic

Almost half of all Americans take a vitamin supplement, and yet many large-scale, placebo-controlled clinical trials of various supplements have found little or no benefit. A new study led by investigators from Brigham and Women’s Hospital suggests an intriguing reason for this: genetic variation may be influencing these effects, increasing risk in some individuals while

Myths about gluten are hard to bust. Intolerance, allergy, sensitivity, hypersensitivity. What is what? Celiac disease is none of these things. It is an autoimmune disorder, where gluten triggers the immune system to attack the gut. It is common, lifelong, and can seriously harm health — but nobody knows for sure what causes it. Now

Large quantities of rich Christmas food appear to boost Danes’ cholesterol levels. Right after the Christmas break, levels are 20% higher than in the summer. So says a new study carried out by researchers from the Department of Clinical Biochemistry at Copenhagen University Hospital and the Department of Clinical Medicine, University of Copenhagen. All that

Scientists at the University of Birmingham have developed a novel eye drop that rapidly reduces sight-threatening scarring to the surface of the eye. The surface of the eye (the cornea) is usually transparent, but scars resulting from eye infection or trauma make it opaque causing blurred vision or in extreme cases complete blindness. Their pre-clinical

A team of researchers from the Singapore University of Technology and Design (SUTD) and Nanyang Technological University (NTU) have developed novel ferrocene-based molecules that impair the malaria parasite’s metabolic function leading to parasite death. Despite concerted efforts for malaria elimination, this deadly disease remains a major health threat to the developing world. The causative agent

Argonne researchers have demonstrated a new technique’s viability for membranes. Whether it’s tap water or a cup of coffee, almost everything we drink passes through some kind of filter. The ability to transform liquids this way is essential to daily life, yet it often rests on relatively delicate membranes that can quickly clog or degrade.

Men with inflammatory bowel disease have four to five times higher risk of being diagnosed with prostate cancer, reports a 20-year study from Northwestern Medicine. This is the first report to show men with inflammatory bowel disease have higher than average PSA (prostate-specific antigen) values, and this group also has a significantly higher risk of

A new study from iPSYCH shows that the infections children contract during their childhood are linked to an increase in the risk of mental disorders during childhood and adolescence. This knowledge expands our understanding of the role of the immune system in the development of mental disorders. High temperatures, sore throats and infections during childhood

A powerful new biochemical platform is fueling the study of a family of enzymes that are promising targets for cancer treatment. Published today in Science Advances, the new method provides a high-resolution view of how these enzymes, called lysine methyltransferases, selectively mark proteins with chemical tags that alter their function. Because of their central role

A study including health data for more than 500,000 children in the U.S. suggests obesity might be to blame for about a quarter (23 to 27 percent) of asthma in children who are obese. This could mean about 10 percent of all kids ages 2 to 17 with asthma — almost 1 million children in

Today, they are visible in nearly every kitchen, so we have grown to be familiar with warming our breakfast without needing whether stove or perhaps a fry pan. This really is convenient, what is dangerous microwave? You most likely needed to learn about the risks of microwaves: about harmful radiation, about how exactly helpful products

Treatment with capivasertib, a drug designed to work against a particular gene mutation found in some tumours, shows signs of being effective in a trial of 35 patients presented today (Tuesday) at the 30th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Dublin, Ireland. The phase 2 trial (EAY131-Y) is part of a larger

An unexpected finding that links a structural heart protein to gene regulation following heart stress suggests potential new avenues for developing heart failure therapies. The work led by University of Iowa heart researcher Long-Sheng Song, MD, focuses on a protein called junctophilin-2 (JP2). Previous work from Song’s lab has shown that JP2 is a structural