A common treatment for Alzheimer’s disease may help people with the earliest stages of the disease maintain mitochondrial function in their muscles in addition to slowing cognitive decline. The first-of-its-kind study is published ahead of print in Function. Research suggests people with Alzheimer’s disease, a form of cognitive impairment, have mitochondrial dysfunction throughout the body.
We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info One batch of an oral solution of metformin, involving 10,452 “units”, is being requested back
In the early days of the COVID-19 pandemic, doctors in Wuhan noticed something surprising. Many of the elderly patients who survived the virus were poor: not exactly the demographic you would expect to fare well in a health crisis. A review of the survivors’ medical records revealed that a significant number suffered from chronic heartburn
Researchers at UT Southwestern announced successful results of a clinical trial for a commonly prescribed weight-loss drug called liraglutide. In adults who are overweight or have obesity combined with high cardiovascular risk, once-daily liraglutide combined with lifestyle interventions significantly lowered two types of fat that have been associated with risk to heart health: visceral fat
A new University of Chicago study has found that the drug masitinib may be effective in treating COVID-19. The drug, which has undergone several clinical trials for human conditions but has not yet received approval to treat humans, inhibited the replication of SARS-CoV-2 in human cell cultures and in a mouse model, leading to much
Scientists have identified a drug that can prevent the virus that causes COVID-19 from binding to human cells, potentially preventing damage to the lung, clot formation and the development of sepsis. The study, led by researchers from RCSI University of Medicine and Health Sciences, is published in PLOS ONE. The researchers identified that a mutation,
International organizations and countries around the world are working to eliminate HIV/AIDS by 2030. To reach this goal, new approaches are needed–particularly among difficult-to-reach groups such as people who inject drugs (PWID), who are 30 times more likely to contract HIV/AIDS compared with the general population. Matthew Akiyama, M.D., assistant professor of medicine at Albert
Weight-loss wonder drug that blitzes body fat may also reduce risk of heart attacks and strokes Rybelsus is a daily pill for obesity and diabetes, approved for use in UK last year It cuts calorie intake by mimicking the effects of naturally occurring hormones A third of those on high doses of the drug lose 20
COVID vaccines and heart inflammation in young adults a ‘likely’ link: CDC panel Fox News medical contributor Dr. Janette Nesheiwat argues the condition is extremely rare and says vaccine benefits outweigh any potential side effects. The Food and Drug Administration granted emergency approval to Roche’s Actemra (tocilizumab) to boost outcomes among hospitalized COVID-19 patients receiving
FDA authorizes third Covid antibody treatment that cuts risk of hospitalization or death by 85% Sotrovimab is the third monoclonal antibody drug to receive approval for use fighting Covid-19, fifth drug overall Believed to be able to reduce Covid hospitalizations and deaths by 85 percent The drug will be the first to have a point
Europe’s medicines watchdog said Monday it had begun evaluating the use of Pfizer BioNTech’s COVID-19 vaccine for 12- to 15-year-olds, after a similar request in the United States. Its possible authorisation for children is seen as a crucial step towards achieving herd immunity. The European Medicines Agency’s human medicines committee “will carry out an accelerated
An independent analysis of the medical trials which formed the final basis of approval by the US Food and Drug Administration (FDA) strongly suggests the drug bremelanotide has very limited effectiveness as a treatment for hypoactive sexual desire disorder (HSDD) in women, and that trial participants preferred a placebo. The analysis, published today in the
A Griffith University-led research team has discovered how a therapeutic target common among debilitating neurodegenerative disorders is activated, which could help accelerate drug development. In a study published in the journal Neuron, the researchers from Griffith University’s Institute for Glycomics, the University of Queensland and Washington University, analyzed the structure and function of a protein
Treating severe COVID-19 patients with the anticancer drug bevacizumab may reduce mortality and speed up recovery, according to a small clinical study in Italy and China that was led by researchers at Karolinska Institutet in Sweden between February and April 2020. On average, blood oxygen levels, body temperature and inflammatory markers significantly improved in patients
A major clinical trial in Canada shows that an inexpensive anti-inflammatory drug called colchicine can significantly reduce the risk of complications and death from COVID-19, bringing “important hope” to sufferers, the lead researcher said Sunday. Jean-Claude Tardif, head of the Montreal Heart Institute (ICM), led the study named “Colcorona,” whose preliminary results were published Friday
Drugmaker Eli Lilly said Thursday its antibody drug can prevent COVID-19 illness in residents and staff of nursing homes and other long-term care locations. It’s the first major study to show such a treatment may prevent illness in a group that has been devastated by the pandemic. Residents and staff who got the drug had
Immunotherapy is one of the most promising approaches to inhibit tumor growth and metastasis by activating host immune functions. However, so far, immunotherapy still exhibits limitations of efficacy and safety, such as huge individual differences in treatment responses, difficulty to work on solid tumors, systemic immune storm and other immunotoxicity. Therefore, the development of advanced
Thousands at risk of blindness set to benefit from a new drug that slows vision loss and can even improve sight Brolucizumab approved for patients with wet age-related macular deterioration The painless yet incurable eye disease is leading cause of blindness in over-55s New jab needs to be given only every 12 weeks rather than
A subcutaneous injection of the immune-boosting drug teclistamab was found to be safe and elicit responses in a majority of patients with relapsed or refractory multiple myeloma, according to findings from a multi-institutional phase I study being presented by Alfred L. Garfall, MD, an assistant professor of Medicine in the division of Hematology-Oncology in the
MONDAY, Oct. 19, 2020 — A recently approved rheumatoid arthritis medication appears to be an effective second-line therapy when biologic treatments start to fail, a new clinical trial reports. Arthritis sufferers treated with upadacitinib had a significantly greater reduction in their symptoms and disease activity than people treated with a standard disease-modifying antirheumatic drug (DMARD),
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