In an important step toward the clinical application of synthetic biology, Rice University researchers have engineered a bacterium with the necessary capabilities for diagnosing a human disease. The engineered strain of the gut bacteria E. coli senses pH and glows when it encounters acidosis, an acidic condition that often occurs during flareups of inflammatory bowel
Many cancer researchers can claim to have devised “smart bombs.” What has been missing is the stealth bomber—a delivery system that can slip through the body’s radar defenses. Oncolytic viruses, or viruses that preferentially kill cancer cells, have been discussed and tested for decades. An oncolytic virus against melanoma was approved by the FDA in
A pandemic can strike at any time. It takes little more than the right roll of genetic dice in a virus circulating among animals, followed by a chance encounter with a person or some go-between species, like pigs or mosquitoes. But as the new coronavirus whips around the world with a speed matched by few
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