Tag: formation

A new study co-authored by University of Colorado Cancer Center researcher Srinivas Ramachandran, Ph.D., shows how DNA segments known as enhancers function in cells. The paper published last month in Molecular Cell highlighted the work from Ramachandran, along with Satyanarayan Rao, both part of the Department of Biochemistry and Molecular Genetics at the CU School

Scientists from Nanjing University and the University of Macau have devised a new approach to extend the survival of transplanted probiotics in vivo, enhancing the efficacy of cancer chemo-/immunotherapies in mice. The paper entitled “smectite promotes probiotic biofilm formation in the gut for cancer immunotherapy,” appears online today in Cell Reports. The gut contains trillions

A sustained state of vigilance will generate a different type of memory than a momentary startle, and these differences are linked to distinct signaling molecules in the brains of mice. Researchers at the RIKEN Center for Brain Science (CBS) have visualized these dynamics in the living mouse brain for the first time, observing fast and

A team of Florida State University researchers used a simple tumor model to show the importance of tissue microenvironment in primary tumor formation. In the journal Developmental Cell, FSU researchers explain how certain signaling pathways define tumor hotspots, tissue microenvironment favorable for tumorigenesis, and show that simple stimulation of a protein can lead directly to

(HealthDay)—Prophylactic mesh implantation reduces the incidence of hernia formation among patients undergoing elective open abdominal surgery but increases early postoperative pain and leads to prolonged wound healing of surgical site infection, according to a study published online Nov. 21 in JAMA Surgery. Andreas Kohler, M.D., from Bern University Hospital in Switzerland, and colleagues performed a

The brain allows organisms to learn and adapt to their surroundings. It does this by literally changing the connections, or synapses, between neurons, strengthening meaningful patterns of neural activity in order to store information. The existence of this process—brain plasticity—has been known for some time. But actually, there are two different types of brain plasticity

Synapses, the structures that allow neurons to pass signals to one another, are essential to neuronal function. Proper formation and responses to stimulation of synapses both during development and in adulthood are fundamental to mammalian brains, but the molecular processes governing formation and modulation of compartmentalized synaptic assemblies are unclear. In a recent study, a

Astronauts go through many physiological changes during their time in spaceflight, including lower muscle mass and slower muscle development. Similar symptoms can occur in the muscles of people on Earth’s surface, too. In fact, it could affect everyone to some extent later in life. “Age-related skeletal muscle disorders, such as sarcopenia, are becoming a greater