Tag: Healthy Aging

Sun Protection to patients with rare genetic disease

Skin cells taken from patients with a rare genetic disorder are up to ten times more sensitive to damage from ultraviolet A (AVA) radiation in laboratory tests, than those from a healthy population, according to new research from the University of Bath. It is hoped that the work, which has involved designing a brand new

Study offers promise for preventing necrotizing enterocolitis in preemies: Preventing inflammatory white blood cell infiltration in the intestine decreases development of necrotizing enterocolitis in animal model

Researchers at Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago, and colleagues, discovered a promising direction toward understanding the development of necrotizing enterocolitis (NEC), a devastating intestinal disease commonly affecting premature infants, in order to treat it. Studying the early cellular events leading to NEC in a mouse

‘Nested sequences’: An indispensable mechanism for forming memories

Repetition is the best method for memorization, for neurons themselves. This is the principle behind what neurobiologists call sequence reactivations: during sleep, neurons in the hippocampus related to a task activate very quickly in turn in a precise order, which consolidates the memory of this task. Sequence reactivations are fundamental for long-term memorization and for

Traditional glaucoma test can miss severity of disease: Study finds variation of exam better assesses central vision damage

The most common tests for glaucoma can underestimate the severity of the condition by not detecting the presence of central vision loss, according to a new Columbia University study. The study, published Nov. 8 in JAMA Ophthalmology, found that administering a variation of the visual field test that better assesses macular damage can improve diagnosis

A new study indicates the possibility to monitor the progression of Alzheimer’s disease by monitoring major brain antioxidant levels using noninvasive techniques

In a breakthrough human study, anti-oxidant, glutathione (GSH), which protects the brain from stress, has been found to be significantly depleted in Alzheimer’s patients compared to normal subjects. As GSH is a very important anti-oxidant that protects the brain from free radicals, the findings give us another measure to use when diagnosing potential for the

Discovery could explain failed clinical trials for Alzheimer’s, and provide a solution

Researchers at King’s College London have discovered a vicious feedback loop underlying brain degeneration in Alzheimer’s disease which may explain why so many drug trials have failed. The study also identifies a clinically approved drug which breaks the vicious cycle and protects against memory-loss in animal models of Alzheimer’s. Overproduction of the protein beta-amyloid is

Male and female tennis players decline at same rate

The physical abilities of male and female tennis stars decline at the same rate as they age, new research shows. Men and women are known to have different patterns of ageing — so University of Exeter scientists were surprised to find “similar patterns of decline” among tennis professionals. Using data on first-serve speed and accuracy

Autobiographical memory tested for early Alzheimer’s detection

Testing how well people remember past events in their lives could help medical professionals make early predictions about who is at risk for developing Alzheimer’s disease, according to a new study from the University of Arizona. Researchers administered an “autobiographical memory” test to a group of 35 healthy adults, about half of whom carry the

Can we predict the long-term outcome of boys with ADHD?

A study published in the August 2018 issue of the Journal of the American Academy of Child and Adolescent Psychiatry(JAACAP) reports on a group of boys diagnosed with ADHD in childhood (when they were, on average, 8 years old) and followed into adulthood (when they were in their early 40s). The goal was to examine

Advancing the search for antibodies to treat Alzheimer’s disease: Two new studies shed light on the most toxic forms of amyloid-beta and how to find antibodies to target these structures

Two new studies published by investigators from Brigham and Women’s Hospital illustrate that not all forms of amyloid-beta (Aβ) protein — the protein thought to initiate Alzheimer’s disease — play an equally menacing role in the progress of the disease. Using a new way of preparing and extracting the protein as well as a new

Brain discovery could block aging’s terrible toll on the mind: Faulty brain plumbing to blame in Alzheimer’s, age-related memory loss — and can be fixed

Aging vessels connecting the brain and the immune system play critical roles in both Alzheimer’s disease and the decline in cognitive ability that comes with time, new research reveals. By improving the function of the lymphatic vessels, scientists at the University of Virginia School of Medicine have dramatically enhanced aged mice’s ability to learn and

Common painkillers triple harmful side effects in dementia: Commonly-prescribed opioid-based painkillers led to harmful side effects tripling in people with dementia

Commonly-prescribed opioid-based painkillers led to harmful side effects tripling in people with dementia. Researchers from the University of Exeter, King’s College London and the University of Bergen are presenting two studies at the Alzheimer’s Association International Conference 2018 (AAIC) highlighting a significant increase in harmful side effects related to the use of commonly prescribed opioid

Key molecule of aging discovered

Every cell and every organism ages sooner or later. But why is this so? Scientists at the German Cancer Research Center in Heidelberg have now discovered for the first time a protein that represents a central switching point in the aging process. It controls the life span of an individual — from the fly to