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Leakage from the blood capillaries is a key mechanism leading to septic shock and multiorgan failure, which affect millions of patients annually worldwide. However, there is no effective way to inhibit the vessel leakiness. A new study by scientists at the University of Helsinki and Wihuri Research Institute demonstrates that vascular leakage can be inhibited

Northwestern Medicine scientists have discovered that some neurons affected by amyotrophic lateral sclerosis (ALS) display hypo-excitability, using a new method to measure electrical activity in cells, according to a study published in Stem Cell Reports. “The excitability changes observed in these patient neurons most likely represent the early steps in the disease process,” said Evangelos

A new CAMH and Institute for Clinical Evaluative Sciences (ICES) study shows that people with schizophrenia account for more than 1 in 10 cases of suicide in Ontario, and that young people are disproportionately affected. “Among people who died by suicide, having a diagnosis of schizophrenia is clearly over-represented,” says Dr. Juveria Zaheer, first author

A large team of researchers from the U.S. and China has succeeded in identifying a number of RNA fragments found in human fat tissue. In their paper published in the journal Science Translational Medicine the group describes their study of the fragments they found and their possible links with obesity. Prior research has reported RNA

The first comprehensive study comparing the outcomes of robotic surgery to those of traditional open surgery in any organ has found that the surgeries are equally effective in treating bladder cancer. The seven-year study, conducted at 15 institutions, including Sylvester Comprehensive Cancer Center, and directed by Dipen J. Parekh, M.D., chair of urology and director

In a study of children with chronic kidney disease (CKD), blood pressure medications reduced protein excretion in the urine, which was linked with a lower risk of disease progression. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN), provide valuable information for monitoring and treating pediatric

Yeah, yeah, there are parenting ‘rules’ most of us live by — but what about on summer vacation? Is it actually OK to let a few rules slide until September? Short answer: yes. Here’s why. Summertime doesn’t just mean longer days, no school and boatloads of sunscreen. Along with the rising temperatures often comes a

Deaths of children under 5 have dropped by nearly 20 percent in just two years in a poor, rural district in Madagascar—despite the island nation having the lowest health-spending level in the world. This transformation echoes the strength of results seen across the last decade in rural Rwanda, where under-5 mortality dropped 60 percent between

(HealthDay)—Before your child goes to a friend’s home to play, find out if there are guns in that home, a leading U.S. medical group advises. Gun injuries are among the top three causes of death among children and teens in the United States, the American Academy of Pediatrics says. “About one-third of families in the

Giving the drug sodium thiosulphate after chemotherapy reduces hearing loss in children treated for liver cancer, according to findings published in the New England Journal of Medicine today. Results from the Cancer Research UK funded SIOPEL-6 clinical trial show that giving sodium thiosulphate (STS), after a type of chemotherapy called cisplatin, reduces hearing loss by

An international team of scientists have developed a new way to screen for age-related cognitive decline at home using a test which asks people to detect sounds and flashes on their laptop or phone. Developed by researchers from Switzerland and the UK, the study shows that the simple, cost-effective test may be used to help

(HealthDay)—Conservative measures to control reflux have limited effect on signs of gastroesophageal reflux (GER) in preterm infants, and pharmacologic treatments should be used sparingly, according to a clinical report published online June 18 in Pediatrics. Eric C. Eichenwald, M.D., from the Children’s Hospital of Philadelphia, and colleagues from the American Academy of Pediatrics’ Committee on

At a research facility in Gabon, one isolated building stands behind an electrified fence, under round-the-clock scrutiny by video cameras. The locked-down P4 lab is built to handle the world’s most dangerous viruses, including Ebola. “Only four people, three researchers and a technician, are authorised to go inside the P4,” said virologist Illich Mombo, who

If there’s one parenting choice that’s guaranteed to polarize, it’s co-sleeping. I’ve experienced the backlash against sharing a bed with my baby firsthand. "But you’re harming your baby!" exclaimed one friend — who swiftly became a former friend — when I casually mentioned over dinner that my healthy, happy 3-month-old bedded in with us every

Thomas Markle — the only person in the world who can get away with calling the new Duchess of Sussex, formerly known to us Americans as just Meghan Markle, by her childhood nickname "Bean" — isn’t exactly shy about talking to the media about his famous daughter. We can’t imagine Meghan and Prince Harry are

Children who are born severely ill or who develop serious illness in the first few weeks of life are often difficult to diagnose, with considerable implications for their short and longer-term care. Whole genome sequencing carried out quickly has the potential to provide an early diagnosis, and thus improve the clinical care of these infants

RNA-Seq is a new next-generation assay that can detect gene fusions in solid tumor cells with high accuracy and excellent reproducibility. According to a new report in The Journal of Molecular Diagnostics, the assay detected 93 percent of gene fusions identified by currently available methods with no false positives. Importantly, gene fusions missed by other

Researchers previously showed that overweight and obese individuals with knee osteoarthritis can reduce pain by 50% and significantly improve function and mobility with a 10% or more weight loss over an 18-month period. The investigators’ latest findings, which are published in Arthritis Care & Research, reveal that a 20% or more weight loss has the

People choose role models who have achieved success in ways that are in line with their own moral values, according to University of Queensland research. Dr. Kim Peters of the UQ School of Psychology examined the competency and moral characters of role models in the workplace and found that people did not blindly follow extraordinary

A team of researchers says it has linked sensitivity to an allergen in red meat to the buildup of plaque in the arteries of the heart. While high saturated fat levels in red meat have long been known to contribute to heart disease for people in general, the new finding suggests that a subgroup of