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Fetal immune system rejects the mother in preterm labor

Preterm labor, a common pregnancy complication, has long been a mystery to scientists. But a new study from UC San Francisco shows it may sometimes happen when the fetal immune system “wakes up” too early and begins to reject the mother, causing the uterus to start contracting. The researchers think the fetal immune system becomes

Ethics debate overdue in human brain research: experts

What if human brain tissue implanted into a pig transferred some of the donor’s self-awareness and memories? Such a scenario, out of reach for now, is becoming more and more conceivable, according to a group of scientists, ethicists, and philosophers who called Wednesday for a debate on the ethics of storing and using human brain

Back in black for singletons trying to find love

Black beats red as the colour of choice when it comes to finding new love, according to new research based on the hit TV series First Dates, which shows that single people wear more of the darker hue when meeting a potential partner for the first time. The study builds on previous research into the

Evening preference linked to higher BMI in type 2 diabetes

(HealthDay)—Evening preference and a later breakfast are associated with elevated body mass index (BMI) in adults with type 2 diabetes, according to a study published online April 13 in Diabetic Medicine. Hataikarn Nimitphong, M.D., from Mahidol University in Bangkok, and colleagues examined the correlations among meal timing, morning-evening preference, and BMI in 210 non-shift workers

Exercise intervention doesn’t improve walking ability in PAD

(HealthDay)—For patients with peripheral artery disease (PAD), a home-based exercise intervention does not improve walking ability over nine months compared with usual care, according to a study published in the April 24 issue of the Journal of the American Medical Association. Mary M. McDermott, M.D., from the Northwestern University Feinberg School of Medicine in Chicago,

In Huntington’s disease, heart problems reflect broader effects of abnormal protein

Researchers investigating a key signaling protein in Huntington’s disease describe deleterious effects on heart function, going beyond the disease’s devastating neurological impact. By adjusting protein levels affecting an important biological pathway, the researchers improved heart function in experimental animals, shedding light on the biology of this fatal disease. “Heart disease is the second leading cause

Patients prefer doctors who engage in face-to-face visits

(HealthDay)—Patients prefer physicians who engage in face-to-face (F2F) clinic visits, rather than those using an examination room computer (ERC), according to a research letter published online April 19 in JAMA Oncology. Ali Haider, M.D., from the University of Texas MD Anderson Cancer Center in Houston, and colleagues conducted a randomized controlled crossover study involving 120

Dementia an extra challenge in natural disasters

Natural disasters are traumatic for anyone involved but the dangers are even greater for people with dementia. A new guide from the QUT-based Dementia Centre for Research Collaboration: Carers and Consumers (DCRC-CC) aims to prepare those who care for people with dementia to cope. Created in a partnership with the Red Cross, the Preparing for

Six-day antibiotic cellulitis treatment resulted in higher rates of relapse than 12-day treatment

Cellulitis treated with a six-day course of intravenous antibiotic flucloxacillin resulted in greater rates of relapse at 90 days post treatment despite having similar short-term results to the 12-day course, according to research presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). Cellulitis, a skin infection that can become life threatening,

MRI technique detects spinal cord changes in MS patients

A Vanderbilt University Medical Center-led research team has shown that magnetic resonance imaging (MRI) can detect changes in resting-state spinal cord function in patients with multiple sclerosis (MS). This first application of these measures in patients living with MS, reported last week in the journal Brain, could lead to new ways to monitor the effectiveness

More cases in E. coli outbreak tied to romaine lettuce

(HealthDay)—The outbreak of E. coli illness tied to tainted Arizona romaine lettuce continues to expand, federal health officials said Wednesday. “Since the last update on April 13, 2018, 18 more ill people have been added to this investigation, bringing the total number to 53,” the U.S. Centers for Disease Control and Prevention said in a

In Romania, distrust of vaccines kills

Measles still claims young lives in Romania, where nearly 40 children have died in an outbreak that many blame on parents being misled by scare stories that vaccinating them is dangerous. Some 12,000 people have contracted measles since late 2016 in the European Union’s second-poorest country, 46 of them died. Among the dead, 39 were

Trials in Africa support conditional day 3 follow-up for children with fever

Children in sub-Saharan African settings with uncomplicated fever may be safely managed with conditional, rather than universal, 3-day follow-up with a community health worker (CHW), according to two cluster-randomized, community-based non-inferiority trials published this week in PLOS Medicine. The trials, conducted by Luke C. Mullany of the Johns Hopkins Bloomberg School of Public Health, Baltimore,

Could statins ease deadly heart condition in rare neuromuscular disease?

In preclinical studies using cell models that mimicked liver cells of patients with the rare disease Friedreich’s ataxia (FA), a widely used cholesterol-lowering drug increased a precursor of HDL (high-density lipoprotein), the “good cholesterol,” according to new research published in PLOS ONE from the Perelman School of Medicine at the University of Pennsylvania. Decreased HDL