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Following a heart attack, the parts of the heart muscle that die do not regenerate into new heart tissue and instead are replaced by scar tissue. Using rodent models, researchers at Baylor College of Medicine are looking for a means to genetically convert this scar tissue into muscle tissue at the cellular level, which could

Most of the roughly 15.5 million cancer survivors in the U.S. receive chemotherapy, and roughly 65 percent develop some degree of the chemotherapy-induced nerve damage known as peripheral neuropathy. Peripheral neuropathy simply means nerves outside of the brain and spinal cord are affected, and symptoms include numbness and tingling in extremities, and in about 30

FT819, an off-the-shelf, T-cell receptor (TCR)-less CD19 CAR T-cell product that could potentially be made more accessible to cancer patients than conventional CAR T-cell therapies showed positive results in preclinical specificity, functionality, and efficacy studies, according to data presented at the AACR Annual Meeting 2018, April 14-18. “Chimeric antigen receptor (CAR) T-cell therapy has shown

Checkpoint inhibitors that block the protein PD-1 are used in melanoma patients after they’ve had surgery to remove their cancer, but not all patients benefit from the immunotherapy. Now a new study from the Abramson Cancer Center of the University of Pennsylvania found that shifting use of anti-PD-1 drugs to before surgery may provide clues

A position statement from the American Academy of Sleep Medicine (AASM) concludes that fatigue and sleepiness are inherent safety risks in the ridesharing industry. Both sleep deprivation and circadian influences leave ridesharing drivers at risk for drowsy driving. The typical schedule for workers in the ridesharing industry may lead to driving after extended periods of

New research published in The Journal of Physiology has indicated why people with paralysis of their limbs and torso are more likely to suffer from sleep apnoea. This knowledge could be used to develop much-need targeted therapies. Obstructive sleep apnoea (OSA) is a sleep disorder in which the upper airway (ranging from the back of

Patients with hepatocellular carcinoma (HCC) waiting for a liver transplant in the USA are now significantly less likely to receive a new liver than they were around a decade ago. A nationwide study presented today at The International Liver Congress 2018 in Paris, France, has confirmed that patients with HCC on the liver transplant list

(HealthDay)—When it comes to a fever, what’s true for kids isn’t necessarily so for adults. Even a slight temperature in a child warrants a call to the doctor. That’s not the case, though, for most fevers in most adults. What’s considered a normal temperature varies from one adult to the next. In general, though, 98.6

A University of Montana researcher and her collaborators have published a new study that reveals increased risks for Alzheimer’s and suicide among children and young adults living in polluted megacities. Dr. Lilian Calderón-Garcidueñas said her group studied 203 autopsies of Mexico City residents ranging in age from 11 months to 40 years. Metropolitan Mexico City

Sitting too much is linked to changes in a section of the brain that is critical for memory, according to a preliminary study by UCLA researchers of middle-aged and older adults. Studies show that too much sitting, like smoking, increases the risk of heart disease, diabetes and premature death. Researchers at UCLA wanted to see

(HealthDay)—For patients with breast cancer, endocrine therapy-induced alopecia (EIA) has a pattern that is similar to androgenetic alopecia, according to a study published online April 11 in JAMA Dermatology. Azael Freites-Martinez, M.D., from the Memorial Sloan Kettering Cancer Center in New York City, and colleagues conducted a retrospective cohort study to characterize EIA in 112

A large register-based study conducted in Sweden has found that statins are associated with a markedly reduced risk of all-cause mortality, liver transplantation, liver cancer, and variceal bleeding in patients with primary sclerosing cholangitis (PSC). The study, which reviewed the records of almost 3,000 patients diagnosed with PSC between 2005 and 2016, also reported a

Because testicular cancer has a 95 percent cure rate, it is easier for men to move on and forget about it. But new research in the Journal of Clinical Oncology shows that it’s prudent for patients to stay in touch with their medical team as they age and to be aware of treatment toxicities. The

Thinking of trying that trendy diet your friends raved about on Instagram? Before you’re ready to declare the latest celebrity fad the best diet plan, check the science first. While many diets promise quick weight loss, they often have a downside. We asked two USC experts to help us separate truth from hype for four

Further evidence that immunotherapy provides long-term survival benefit for patients with lung cancer was presented today at ELCC 2018 (European Lung Cancer Congress) in Geneva, Switzerland. Researchers presented the three-year survival results of the randomised phase 2 POPLAR trial in second line, which is the longest follow-up reported to date with anti-programmed death ligand 1

A Purdue University-affiliated startup has devised a way to map arteries in the roof of a person’s mouth to help avoid complications and improve outcomes in oral surgery. Starfish Engineering LLC has developed a method using light to image arteries and lesions through the tissue in the roof of the mouth. Surgeons working in the

(HealthDay)—Whole body computed tomography (WBCT) is not associated with reduced mortality compared with a selective CT approach among children with blunt trauma, according to a study published online April 9 in JAMA Pediatrics. James A. Meltzer, M.D., from the Albert Einstein College of Medicine in Bronx, N.Y., and colleagues conducted a retrospective multicenter cohort study

(HealthDay)—For older adults, dipeptidyl peptidase 4 inhibitors (DPP-4Is) are not associated with increased risk of acute pancreatitis, according to a study published online April 4 in Diabetes Care. Jin-Liern Hong, Ph.D., from the University of North Carolina at Chapel Hill, and colleagues examined the risks of acute pancreatitis among U.S. Medicare beneficiaries, aged 66+ years,

(HealthDay)—Parents, you may be able to stop feeling guilty about letting your toddlers play video games—as long as you’re playing with them. That’s the suggestion of a small study on the effects of touchscreen technology on kids’ development. The research dovetails with growing concern that toddlers might be harmed as technology takes center stage in

(HealthDay)—Pharmacists have been involved in the recent progress made toward reducing hospital-acquired infections (HAIs), according to an article published in Drug Topics. According to the latest data from the U.S. Centers for Disease Control and Prevention, between 2008 and 2016 there was a 50 percent decrease in central line-associated bloodstream infections as well as other