Like most other kids with covid, Dante and Michael DeMaino seemed to have no serious symptoms. Infected in mid-February, both lost their senses of taste and smell. Dante, 9, had a low-grade fever for a day or so. Michael, 13, had a "tickle in his throat," said their mother, Michele DeMaino, of Danvers, Massachusetts. At
The ongoing COVID-19 pandemic is caused by the severe acute respiratory syndrome-2 (SARS-CoV-2), an RNA virus that belongs to the family Coronaviridae. According to research, coronavirus disease 2019 (COVID-19) patients often suffer from neurological disorders like strokes, lost taste or smell, memory loss, confusion, and delirium. By comparing the symptoms associated with other coronavirus infections,
An estimated 10% to 30% of people who get Covid-19 suffer from lingering symptoms of the disease, or what’s known as “long Covid.” Judy Dodd, who lives in New York City, is one of them. She spent nearly a year plagued by headaches, shortness of breath, extreme fatigue and problems with her sense of smell,
Prolonging a cellular defense response to inflammation could help regenerate the protective coating of axons that is degraded in diseases such as multiple sclerosis (MS), according to a Northwestern Medicine study published in eLife. There are currently no FDA-approved drugs that have been shown to effectively regenerate this coating, called myelin. This new strategy could
The coronavirus disease 2019 (COVID-19) pandemic has claimed well over 2.4 million lives, but its long-term sequelae are still being identified. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produces an infection that may be associated with a wide spectrum of disease, from asymptomatic to critical or terminal respiratory failure or multi-organ dysfunction. A new
The coronavirus disease 2019 (COVID-19) is a transmissible viral disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen responsible for the ongoing global pandemic. The virus was first detected in Wuhan, China, at the end of 2019 and to date has caused over 109 million infections worldwide. With over 2.4 million
The gastrointestinal (GI) tract begins in the mouth and works its way down the esophagus, through the stomach, small and large intestines and rectum, before terminating at the anus. Bleeding or hemorrhaging anywhere along this pathway may be acute or chronic and can be due to a host of factors. The key symptoms are hematemesis
Takayasu'sarteritis (TAK) is a rare condition characterized by a cascade of inflammatory processes. TAK involves vasculitis or inflammation of blood vessels such as the aorta and its major branches. Inflammation of these blood vessels leads to thickening of the walls of the vessels, which, in turn, causes stenosis and ultimately ischemia of the body parts
How do you multiplex an immunoassay? There are two main ways of multiplexing an immunoassay; by separating the individual assays into different spaces (spatial separation) or by immobilizing antibodies onto different beads based on what they target. Jarun Ontakrai | Shutterstock Spatial separation is typically achieved by placing antibodies in different parts of a shared
Inflammation of the pancreas is referred to as pancreatitis. The pancreas is a flat tadpole-shaped gland located at the back of the stomach in the upper abdomen; it releases certain enzymes and hormones which help in digestion and aids in regulating sugar metabolism in the body. Pancreatitis may manifest in both severe and acute forms.
Skip to: Stroke and its Pathways Biomarkers and Risk Scores What are the Benefits of Using Biomarkers? Stroke, a complication of atrial fibrillation, can be fatal. Identification of biomarkers to predict stroke may help treat those at highest risk. Given the association between atrial fibrillation and other poor disease outcomes, biomarker identification has applications for
Scleroderma, a chronic and currently incurable orphan disease where tissue injury causes potentially lethal skin and lung scarring, remains poorly understood. However, the defining characteristic of systemic sclerosis, the most serious form of scleroderma, is irreversible and progressive scarring that affects the skin and internal organs. Published in iScience, Michigan Medicine’s Scleroderma Program and the
Parkinson’s disease usually is thought of as a movement disorder. People with Parkinson’s typically first develop a tremor in one hand, followed by slowed movement, stiffness and loss of balance. But within 10 years of diagnosis, more than three-quarters of Parkinson’s patients also develop cognitive problems such as difficulty with memory and with performing sequential
Depression has traditionally been linked to increased inflammation. Innovative research by psychologist Eiko Fried refutes this popular assumption. He shows that specific depression symptoms such as sleeping problems explain this relationship. Publication in Psychological Medicine . Over the past few decades, there have been many studies into the relationship between depression and inflammation in the
Often used syringes and reflections in knee pain according to a study, often ineffective. For the “fact check healthcare” of the Bertelsmann Foundation, the Harding center for Risk literacy at the Max-Planck-Institute in Berlin analyzed the current reports. Joint reflections, hyaluronic acid and Corticosteroid injections showed accordingly, in the case of osteoarthritis, only a very
Growing evidence shows that the brain’s dopamine system, which drives motivation, is directly affected by chronic, low-grade inflammation. A new paper proposes that this connection between dopamine, effort and the inflammatory response is an adaptive mechanism to help the body conserve energy. Trends in Cognitive Sciences published the theoretical framework developed by scientists at Emory
It’s the third deadliest cardiovascular diagnosis, but doctors are still often stumped to explain why 40% of patients experience unprovoked venous thromboembolism (VTE). And after a patient has dealt with these dangerous blood clots once, a second and subsequent events become much more likely. New research from a team of University of Michigan scientists may
Aging affects every living organism, but the molecular processes that contribute to aging remain a subject of debate. While many things contribute to the aging process, one common theme in animal aging is inflammation—and this may be amplified by a class of selfish genetic elements. The human genome is littered with selfish genetic elements—repetitive elements
St. Jude Children’s Research Hospital scientists have discovered a subset of helper T cells that may help to redefine understanding and treatment of chronic, debilitating inflammatory disorders. The research appears today as an advance online publication in the journal Nature. The study focused on a family of helper T cells called Th17 cells. Th17 cells
Each year 15 million infants are born preterm and face high risks of short- and long-term complications, including sepsis, severe inflammation of the gut, and neurodevelopmental disorders. A new report in the American Journal of Pathology demonstrates a link between prenatal inflammation and postnatal immune status and organ function in preterm pigs, suggesting that early
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