Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a neurodegenerative disease that strikes nearly 5,000 people in the U.S. every year. About 10% of ALS cases are inherited or familial, often caused by an error in the C9orf72 gene. Compared to sporadic or non-familial ALS, C90rf72 patients are considered to have a
Primary sclerosing cholangitis (PSC) is a rare chronic inflammatory disease of the bile ducts and is difficult to treat, since its causes have not yet been adequately researched. Using RNA sequencing, an international research consortium led by Michael Trauner, Head of MedUni Vienna’s Division of Gastroenterology and Hepatology (Department of Medicine III), has now identified
MONDAY, Nov. 30, 2020 — Multisystem inflammatory syndrome in children (MIS-C) occurs more often among Black and Hispanic children than White children, according to a research letter published online Nov. 30 in JAMA Network Open. Ellen H. Lee, M.D., from the New York City (NYC) Department of Health and Mental Hygiene (DOHMH), and colleagues used
Detailed analysis from the epicentre of the Italian COVID-19 outbreak describes increase in cases of rare Kawasaki-like disease in young children, adding to reports of similar cases from New York, USA and South East England, UK. Syndrome is rare and experts stress that children remain minimally affected by SARS-CoV-2 infection overall. Doctors in the Bergamo
Relatively new research findings indicating that the earliest stages of Parkinson’s disease (PD) may occur in the gut have been gaining traction in recent years. In a review published in the Journal of Parkinson’s Disease, Tomasz Brudek, Ph.D., evaluates evidence for the association between inflammatory bowel disease (IBD) and PD and proposes directions for future
New research from King’s College London has found that a diet low in fermented carbohydrates has improved certain gut symptoms and improved health-related quality of life for sufferers of inflammatory bowel disease (IBD). In a paper published today in Gastroenterology a team of researchers carried out a trial of a diet low in fermentable oligosaccharides,
A unique discovery about the nature of neutrophils—the most numerous white blood cells in the body—may lead to new models for diagnosing and tracking inflammatory diseases such as cancer and osteoarthritis. The “first responders” of the body, neutrophils are a class of leukocyte immune cell in the “innate” immune system, which deals with acute infections.
A team of researchers affiliated with several institutions in the U.S. and one in the U.K. has found that blocking a certain inflammatory pathway in mice protects tendons from injury. In their paper published in the journal Science Translational Medicine, the group describes their study of tendinopathies and possible ways to prevent them. Most people
A novel way in which the inflammatory response to pain is regulated has been described in the open-access journal eLife. The results add to our understanding of the mechanisms that cause increased sensitivity to pain in response to injury and inflammation, and could pave the way for more effective therapies. Inflammatory hyperalgesia, the hypersensitivity to
The Good Doctors Guide: Meet the best doctors for gall bladder and learn the cutting-edge treatments for inflammatory bowel disease We have identified the country’s top consultants — as judged by their peers The views of more than 260 consultants across seven specialities are revealed The consultants with the most votes from their peers made
Interfering with inflammatory signals produced by heart muscle cells might someday provide novel therapeutic strategies for atrial fibrillation, according to an international team of researchers who have published their findings in the journal Circulation. “Atrial fibrillation is the most common heart arrhythmia, and it is particularly observed in the elderly human population, which is growing
The two most common types of inflammatory bowel disease are ulcerous colitis and Crohn’s disease. These are diagnosed via endoscopy and gut biopsy. The diagnosis is often difficult, and the wrong diagnosis may have severe consequences for patients, because the treatments and medications are different between the two diseases. The development of new and improved
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