New research in mice finds that deficiency in one small component of a signaling pathway may protect against artery stiffening and subsequent kidney disease associated with a high-fat, high-sugar diet. The study is published in the American Journal of Physiology-Renal Physiology. Consuming a western diet—typically high in fat and refined carbohydrates, including sugar—is associated with
How cells recognize pathogens and alert the immune system swiftly is a fundamental process of high importance for the survival of any species, including humans. A key role is ascribed to so-called adapters—little molecular platforms inside cells where signals from pathogen detectors are integrated for safety and accuracy and conveyed to lasting signals leading to
TUESDAY, Feb. 18, 2020 — Women remain underrepresented in heart disease research, even though it’s the leading cause of death among women worldwide, researchers say. Women accounted for less than 40% of all people enrolled in cardiovascular clinical trials from 2010 through 2017, according to a study published Feb. 17 in the journal Circulation. “One
Scientists at Rutgers University-Newark have discovered that when a key protein needed to generate new brain cells during prenatal and early childhood development is missing, part of the brain goes haywire—causing an imbalance in its circuitry that can lead to long-term cognitive and movement behaviors characteristic of autism spectrum disorder. “During brain development, there is
Scientists find ‘missing link’ in allergic reactions to popular skin creams: Fragrances, alcohols and immune protein combine to cause itchy rashes Contact dermatitis allergic reactions have been on the rise as the skin care and cosmetic industry has grown But scientists have been unsure how skin creams and other products trigger the itchy red rash
Baking is as much of a science as it is a culinary art. Sometimes you can toss the ingredients listed on the box in a bowl, stir them altogether and end up with, at the very least, something edible. But then there are recipes that call for what seems like unnecessary steps, such as sifting
The producer Cesare Fiorucci S. p. a. informs about the recall of the article “Classic Salami Il Gusto d’Italia” and “Salametto Fiorucci”. The company announced that is missing on deer packing due to a printing error, the note on contained Milk allergens. The producer Cesare Fiorucci S. p. a. calls for consumers who are allergic
Over the past few years, matcha has become such a popular drink that you’ll find it offered at almost any coffee shop across the country. And unlike most food trends, matcha has maintained its cult wellness status—which means it’s time to get to know exactly what matcha powder is and its good-for-you benefits. Matcha is
An approved drug normally used to treat fungal infections could also do the job of a protein channel that is missing in the lungs of people with cystic fibrosis, operating as a prosthesis on the molecular scale, says new research from the University of Illinois and the University of Iowa. Cystic fibrosis is a lifelong
The disappearance of an entire brain region should be cause for concern. Yet, for decades scientists have calmly maintained that one brain area, the subplate, simply vanishes during the course of human development. Recently, however, research has revealed genetic similarities between cells in the subplate and neurons implicated in autism—leading a team of Rockefeller scientists to
Scientists have discovered that the absence of a specific protein in cells lining the esophagus may cause inflammation and tissue damage in people with eosinophilic esophagitis (EoE). EoE affects as many as 150,000 people in the United States, many of whom are children. People with EoE experience difficult or painful swallowing, vomiting and nutritional problems
Chrissy Teigen is enjoying her 2018 Met Gala — from the comfort of her couch. The pregnant model, 32, shared her view on Instagram where she jokingly said she couldn’t wait for her “turn” on the steps at the Metropolitan Museum of Art. “waiting for my turn on the carpet at #metgala!!!! always an honor!!!” she
Hospitals in the UK are increasingly likely to recognise that a patient has dementia after they’ve been admitted for a different reason, finds a new UCL-led study, but it is still only recognised in under two-thirds of people. This is the first study to identify an improvement in dementia diagnosis in hospitals over time, and
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