Tag: missing

Missing sodium-channel component may protect against diet-induced artery stiffening

New research in mice finds that deficiency in one small component of a signaling pathway may protect against artery stiffening and subsequent kidney disease associated with a high-fat, high-sugar diet. The study is published in the American Journal of Physiology-Renal Physiology. Consuming a western diet—typically high in fat and refined carbohydrates, including sugar—is associated with

Missing component of innate immune signaling identified

How cells recognize pathogens and alert the immune system swiftly is a fundamental process of high importance for the survival of any species, including humans. A key role is ascribed to so-called adapters—little molecular platforms inside cells where signals from pathogen detectors are integrated for safety and accuracy and conveyed to lasting signals leading to

Women Patients Still Missing in Heart Research

TUESDAY, Feb. 18, 2020 — Women remain underrepresented in heart disease research, even though it’s the leading cause of death among women worldwide, researchers say. Women accounted for less than 40% of all people enrolled in cardiovascular clinical trials from 2010 through 2017, according to a study published Feb. 17 in the journal Circulation. “One

Missing protein in brain causes behaviors mirroring autism

Scientists at Rutgers University-Newark have discovered that when a key protein needed to generate new brain cells during prenatal and early childhood development is missing, part of the brain goes haywire—causing an imbalance in its circuitry that can lead to long-term cognitive and movement behaviors characteristic of autism spectrum disorder. “During brain development, there is

Scientists find 'missing link' in allergic reactions to cosmetics

Scientists find ‘missing link’ in allergic reactions to popular skin creams: Fragrances, alcohols and immune protein combine to cause itchy rashes Contact dermatitis allergic reactions have been on the rise as the skin care and cosmetic industry has grown  But scientists have been unsure how skin creams and other products trigger the itchy red rash 

In five Federal States: the manufacturer recalls Salami

The producer Cesare Fiorucci S. p. a. informs about the recall of the article “Classic Salami Il Gusto d’Italia” and “Salametto Fiorucci”. The company announced that is missing on deer packing due to a printing error, the note on contained Milk allergens. The producer Cesare Fiorucci S. p. a. calls for consumers who are allergic

Scientists solve the case of the missing subplate, with wide implications for brain science

The disappearance of an entire brain region should be cause for concern. Yet, for decades scientists have calmly maintained that one brain area, the subplate, simply vanishes during the course of human development. Recently, however, research has revealed genetic similarities between cells in the subplate and neurons implicated in autism—leading a team of Rockefeller scientists to

Eosinophilic esophagitis may be due to missing protein

Scientists have discovered that the absence of a specific protein in cells lining the esophagus may cause inflammation and tissue damage in people with eosinophilic esophagitis (EoE). EoE affects as many as 150,000 people in the United States, many of whom are children. People with EoE experience difficult or painful swallowing, vomiting and nutritional problems

Hospitals often missing dementia despite prior diagnosis

Hospitals in the UK are increasingly likely to recognise that a patient has dementia after they’ve been admitted for a different reason, finds a new UCL-led study, but it is still only recognised in under two-thirds of people. This is the first study to identify an improvement in dementia diagnosis in hospitals over time, and