The brain processes information using both slow and fast currents. Until now, researchers had to use electrodes placed inside the brain in order to measure the latter. For the first time, researchers from Charité – Universitätsmedizin Berlin and the Physikalisch-Technische Bundesanstalt (PTB), Berlin Institute, successfully visualized these fast brain signals from the outside – and
A technique called percutaneous peripheral nerve stimulation yields “impressive” reductions in pain scores and opioid use during the first week after common orthopedic surgery procedures, concludes a randomized clinical trial published Online First in Anesthesiology, the official peer-reviewed journal of the American Society of Anesthesiologists (ASA), today. The benefits of postoperative nerve stimulation were “much
We all feel physical pain in different ways, but people with nerve injuries often have a dysfunctional pain suppression system, making them particularly prone to discomfort. Now researchers have uncovered that virtual reality (VR) can reduce types of pain typically seen in patients with nerve injuries – and that VR can boost the dysfunctional pain
Using genetic engineering, researchers at UT Southwestern and Indiana University have reprogrammed scar-forming cells in mouse spinal cords to create new nerve cells, spurring recovery after spinal cord injury. The findings, published online today in Cell Stem Cell, could offer hope for the hundreds of thousands of people worldwide who suffer a spinal cord injury
Amyloid plaques are aggregates of misfolded proteins that form in the spaces between nerve cells. These abnormally configured proteins are thought to play a central role in Alzheimer's disease. The amyloid plaques first develop in the areas of the brain concerned with memory and other cognitive functions. The amyloid hypothesis Amyloid plaques form when pieces
TUESDAY, Nov. 10, 2020 — Low-frequency spinal cord stimulation (SCS) may be effective for treating painful diabetic neuropathy (DN), according to a study scheduled for presentation at the 19th Annual Pain Medicine Meeting, a meeting of the American Society of Regional Anesthesia and Pain Medicine, held virtually from Nov. 20 to 22. Erika Petersen, M.D.,
Various diseases of the digestive tract, for example severe intestinal inflammation in humans, are closely linked to disturbances in the natural mobility of the intestine. What role the microbiome—i.e. the natural microbial community colonizing the digestive tract—plays in these rhythmic contractions of the intestine, also known as peristalsis, is currently the subject of intensive research.
Mother, 47, claims wearing hair bobbles on her wrist for 30 years has given her carpal tunnel syndrome Lisa McLennan, from British Columbia, has developed carpal tunnel syndrome A friend told her she had been warned to stop wearing elastic on her wrist The common nerve condition causes pain and numbness in the hands and
After nerve injury, the protein complex mTORC1 takes over an important function in skeletal muscle to maintain the neuromuscular junction, the synapse between the nerve and muscle fiber. Researchers at the University of Basel’s Biozentrum have now shown that the activation of mTORC1 must be tightly balanced for a proper response of the muscle to
Increasing the levels of the anti-aging protein hormone Klotho improves the neurological deficits and prolongs life span in an experimental model with Amyotrophic Lateral Sclerosis (ALS). In addition, brain immune cells called microglia play an important role in protecting the brain against inflammation and, likely, motor neuron loss in this model. ALS or Lou Gehrig’s
Post-traumatic stress disorder, or PTSD, is a mental condition caused by a traumatic event. People with PTSD may experience intrusive memories, negative thoughts, anxiety and chronic pain. The condition is typically treated with a combination of psychotherapy, anti-depressants and anti-anxiety medications. It’s this connection between mental health and pain that interests Imanuel Lerman, MD, associate
THURSDAY, Jan. 17, 2019 — Two patients diagnosed with acute flaccid myelitis and upper-extremity neuropathy who were treated with peripheral nerve transfer continue to demonstrate functional recovery at two years, according to a case series recently published in Pediatric Neurology. Eliana B. Saltzman, M.D., of the Hospital for Special Surgery in New York City, and
A team of researchers affiliated with several institutions in India has developed a topical get that can be used by farmers to prevent nerve damage due to chemical crop spraying. In their paper published in the journal Science Advances, the group describes how they made the gel and how well it worked when tested on
For adults over age 65, surgical complications can dampen not only their physical health but also their mental sharpness, with more than half of high-risk cases declining into delirium. In research published this week in the journal Brain Stimulation, Duke University scientists show in a mouse model that a current treatment for seizures can also
The National Institute of Mental Health suggest that over 16 million people in the United States have had at least one episode of major depression in the past year. Of these, more than 10 million adults report that the condition severely impaired their quality of life. There are a variety of treatments available for depression,
People with depression who are treated with nerve stimulation experience significant improvements in quality of life, even when their depression symptoms don’t completely subside, according to results of a national study led by researchers at Washington University School of Medicine in St. Louis. The study involved nearly 600 patients with depression that could not be
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