Tag: neurodegenerative

A Griffith University-led research team has discovered how a therapeutic target common among debilitating neurodegenerative disorders is activated, which could help accelerate drug development. In a study published in the journal Neuron, the researchers from Griffith University’s Institute for Glycomics, the University of Queensland and Washington University, analyzed the structure and function of a protein

New research has shed light on the origins of spinocerebellar ataxia type 7 (SCA7) and demonstrates effective new therapeutic pathways for SCA7 and the more than 40 other types of spinocerebellar ataxia. The study, which appears online Monday on the website of the journal Neuron, implicates metabolic dysregulation leading to altered calcium homeostasis in neurons

Toxic algal blooms can be devastating to natural waterways, robbing them of oxygen, creating dead zones, and sickening people and animals. However, they may also be beneficial, potentially helping combat the progression of neurodegenerative disease, a URI College of Pharmacy study is showing. Assistant Professor of Biomedical and Pharmaceutical Sciences Matthew Bertin is teaming up

Korean researchers have identified the inhibition of autophagy in microglia, brain immune cells. It is expected to help develop treatments for Alzheimer’s disease which occur due to the inhibition of autophagy. Alzheimer’s disease (AD) is the most representative degenerative brain disease, accounting for 60 to 80 percent of all dementia cases. In search for new

Researchers from the University of Leicester have shed new light on how neurons in the brain communicate with one another. This could potentially help in our understanding of how and why a range of neurodegenerative diseases occur. The team, led by Dr Joern Steinert from the MRC Toxicology Unit at the University of Leicester, has