Tag: Parkinson’s

Researchers from the Quadram Institute have carried out a meta-analysis of the gut microbiome in Parkinson’s disease, giving the clearest picture to date of the changes associated with the condition. By re-analyzing data from ten different studies, a common pattern of changes in the abundance of bacteria types in Parkinson’s disease emerges, suggesting that the

Parkinson’s disease usually is thought of as a movement disorder. People with Parkinson’s typically first develop a tremor in one hand, followed by slowed movement, stiffness and loss of balance. But within 10 years of diagnosis, more than three-quarters of Parkinson’s patients also develop cognitive problems such as difficulty with memory and with performing sequential

People with Parkinson’s disease who participate in a special, non-contact boxing program may have better quality of life and be more likely to exercise than those who do not participate, according to a preliminary study released today that will be presented at the American Academy of Neurology’s 72nd Annual Meeting in Toronto, Canada, April 25

Parkinson’s patients’ motor and non-motor symptoms were improved with a weekly exercise regimen that included physical and cognitive tasks, according to new research presented today (18 December) at The Physiological Society early career conference, Future Physiology 2019: Translating Cellular Mechanisms into Lifelong Health Strategies. Parkinson’s Disease is a chronic neurodegenerative disease that can lead to

A clinical trial investigating the repurposed cancer drug nilotinib in people with Parkinson’s disease finds that it is reasonably safe and well tolerated. Researchers also report finding an increase in dopamine, the chemical lost as a result of neuronal destruction, and a decrease in neurotoxic proteins in the brain among study participants. Finally, they say

Relatively new research findings indicating that the earliest stages of Parkinson’s disease (PD) may occur in the gut have been gaining traction in recent years. In a review published in the Journal of Parkinson’s Disease, Tomasz Brudek, Ph.D., evaluates evidence for the association between inflammatory bowel disease (IBD) and PD and proposes directions for future

Suffering from tremor can be very frustrating and reduce the quality of life for many people. This includes people suffering from Parkinson’s, multiple sclerosis or spinal cord injury and a relatively high fraction of the elderly. Today, there are no effective treatments for tremor, and thus, there is great potential in finding medications that can

Officials recall MORE batches of two drugs for Parkinson’s and epilepsy amid fears they were stored wrongly and could be ineffective Neupro and Vimpat are being recalled by the UK’s medicines regulator  There are concerns they were wrongly stored and may not work properly There was a recall of the same drugs from a different

More than three decades ago, scientists discovered that a chemical found in a synthetic opioid, MPTP, induced the onset of a form of Parkinson’s disease. In a new study led by scientists from the School of Veterinary Medicine, researchers found that an enzyme in the body can metabolize compounds formed in the brain from alkaloids

Patients who had their appendix removed were more likely to develop Parkinson’s disease than those whose appendix remained in place, according to the largest study to address the relationship between the two conditions. The retrospective study involving more than 62 million patient records from 26 health systems will be presented at Digestive Disease Week® (DDW)

FRIDAY, March 1, 2019 — It may be possible to restore brain cells damaged by Parkinson’s disease and reverse a patient’s condition, something no current treatment can do, according to British researchers who conducted potentially groundbreaking clinical trials. They cautioned the trial was small — just 41 patients — and the research is still in

For most of human history Parkinson’s disease (PD) has been a rare disorder. However, demography and the by-products of industrialization a now contributing to an impending a Parkinson’s pandemic, according to experts writing in a supplement to the Journal of Parkinson’s Disease. They say that this pandemic can be addressed by the Parkinson’s community forming

That moment when you step on the gas pedal a split second before the light changes, or when you tap your toes even before the first piano note of Camila Cabello’s “Havana” is struck. That’s anticipatory timing. One type relies on memories from past experiences. The other on rhythm. Both are critical to our ability

Hope of a Parkinson’s breakthrough as experts transplant MILLIONS of stem cells into a patient’s brain ‘to regrow parts ravaged by the disease’ Experts at Kyoto University in Japan performed the first-of-its-kind procedure The man is in his 50s and is one of seven people who will take part in the trial  The procedure has

In experiments performed in mice, Johns Hopkins researchers report they have identified the cascade of cell death events leading to the physical and intellectual degeneration associated with Parkinson’s disease. Results of the study, published Nov. 2 in Science, suggest promising new targets for drugs that could interrupt Parkinson’s disease progression. The study, the researchers say,

An interdisciplinary and international research group led by Dr. Volker Busskamp from the Center for Regenerative Therapies Dresden at the TU Dresden (CRTD) has decoded the regulatory impact on neuronal survival of a small non-coding RNA molecule, so-called miRNA, at the highest resolution to date. This deciphering of gene regulation primes applications for strengthening neurons

Diagnosed with Parkinson’s at just 35: Woman who suffered bloating and put her inability to apply eyeliner down to clumsiness turned out to have incurable nerve disease Claire Jones, now 38, has young onset Parkinson’s disease which is incurable She first noticed something was wrong when she couldn’t stop her hand shaking Now the condition

Researchers have modified the protein Nurr1 so that it can enter cells from the outside. Nurr1 deficiency may be one of the causes of Parkinson’s disease. Even though Nurr1 has been discussed as a potential target for the treatment of Parkinson’s disease, it is unusable in its normal form, as it cannot penetrate cells. A

Almost two-thirds of non-diabetic patients with Parkinson’s disease (PD) may be insulin resistant, despite having normal blood sugar, report scientists in the Journal of Parkinson’s Disease. Their findings suggest that insulin resistance in PD is a common and largely undetected problem, especially in patients who are overweight. Reduced glucose tolerance has long been recognized as

The cerebral cortex is a highly developed brain region, which allows intellectual functions such as conscious perception, anticipation of events and language. These functions are mediated by specific sets of neuronal circuits. To understand how these circuits emerge during development, researchers from the University of Geneva (UNIGE), Switzerland, in collaboration with an American team, investigated