Tag: promise

The use of regenerative medicine to lessen chronic pain holds enormous potential, and the body of evidence to support the practice is growing, said Alexios Carayannopoulos, DO, MPH, DABPMR, chief of the departments of physical medicine and rehabilitation at Rhode Island Hospital and Newport Hospital, chief of the division of physical medicine and rehabilitation of

In a small, early study, a vaccine for type 1 diabetes helped preserve the body’s natural production of insulin, at least in a subset of newly diagnosed patients. In patients with type 1 diabetes, the body’s immune system attacks the beta cells in the pancreas that produce insulin, a hormone that’s necessary for cells to

Almost all patients who received a new treatment for highly drug-resistant tuberculosis are still clear of the disease two years after a medical trial in South Africa, findings from a long-term study showed Thursday. By comparison, “five years ago if you were diagnosed with a drug resistant TB, at five years after diagnosis, eighty percent

Researchers from Cleveland Clinic’s Global Center for Pathogen Research & Human Health have developed a promising new COVID-19 vaccine candidate that utilizes nanotechnology and has shown strong efficacy in preclinical disease models. According to new findings published in mBio, the vaccine produced potent neutralizing antibodies among preclinical models and also prevented infection and disease symptoms

A subcutaneous injection of the immune-boosting drug teclistamab was found to be safe and elicit responses in a majority of patients with relapsed or refractory multiple myeloma, according to findings from a multi-institutional phase I study being presented by Alfred L. Garfall, MD, an assistant professor of Medicine in the division of Hematology-Oncology in the

An experimental vaccine, designed to enlist the body’s own immune system to target cancer cells, has shown promise for treating and preventing cancer in mice. The vaccine was created to target a gene called KRAS that is involved in the development of many types of cancer, including lung, bowel and pancreatic cancer. Researchers from the

An innovative use of focused ultrasound being pioneered at the University of Virginia School of Medicine is showing promise against glioblastoma, the deadliest brain tumor, and could prove useful against other difficult-to-treat cancers. The technique hits cancer cells with a drug that sensitizes them to sound waves, then blasts them with focused ultrasound. The sound

A collaborative team of scientists has made a successful proof-of-principle demonstration of an advanced HIV vaccine strategy—an approach that may also work in protecting people from an array of other deadly infectious diseases. The team, led by scientists at Scripps Research, also included the Ragon Institute of Massachusetts General Hospital, MIT and Harvard University; the

A drug used to treat chronic myeloid leukemia appears to be more effective at stopping a type of medulloblastoma in mouse models than existing treatments for the deadly pediatric brain tumor, reports a multi-institutional team led by researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego. In the study,

They promise to be better than your go-to treatments, but are they really worth the cost of a medicine cabinet upgrade, CAROLINE JONES asks While many breakthroughs are an improvement, sometimes older is better Experts were asked to assess which new treatments are worth the upgrade   All medicines mentioned here are available from High Street

Scientists use ECSTASY to ‘cure alcoholics’: Four people give up heavy drinking after taking two doses of MDMA alongside psychotherapy in eight-week trial, study claims Scientists from Imperial College London teamed up with mental health workers They trialled a combination of counselling with taking the recreational drug None of the four people were drinking harmfully

Treatments that prevent recurrence of types of stroke and dementia caused by damage to small blood vessels in the brain have moved a step closer, following a small study. The drugs—called cilostazol and isosorbide mononitrate—are already used to treat other conditions, such as heart disease and angina. This is the first time they have been

Researchers from the USA (Kansas State University) and the Republic of Ireland (the National University of Ireland Galway) have completed a successful initial test of a new microwave thermal ablation technique, which could eventually be used to treat Conn’s syndrome. Conn’s syndrome occurs when a benign adrenal gland adenoma causes the production of excess aldosterone,

The medicinal powers of aspirin, digitalis, and the anti-malarial artemisinin all come from plants. A Salk Institute discovery of a potent neuroprotective and anti-inflammatory chemical in a native California shrub may lead to a treatment for Alzheimer’s disease based on a compound found in nature. The research appears in the February 2019 issue of the

Low-protein high-carbohydrate diets may be the key to longevity, and healthy brain ageing in particular, according to a new mice study from the University of Sydney. Published today in Cell Reports, the research from the University’s Charles Perkins Centre shows improvements in overall health and brain health, as well as learning and memory in mice

Failed back surgery (continued low back and leg pain after surgery) is relatively common. With each reoperation, success, as defined by pain reduction, becomes less likely and most patients do not improve. However, preliminary studies using a simple procedure to remove scar tissue or adhesions suggests a new treatment could help those with post-surgical, chronic

Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers who had not previously been treated with a HER2-targeted therapeutic, according to data from a phase I clinical trial presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3. Among 11

A tumor-specific vaccine combined with an immune checkpoint inhibitor shrank tumors in one third of patients with incurable cancer related to the human papilloma virus (HPV) in a phase II clinical trial led by investigators at The University of Texas MD Anderson Cancer Center and reported in JAMA Oncology. “That encouraging response rate is about

Mushrooms from the Far East contain natural chemical compounds that could be used for the design of the novel drugs with highly specific anti-tumor activities and low toxicity. These compounds may offer new avenues for oncology, providing physicians with either standalone alternatives to chemotherapy, chemopreventive medicines, or drugs to be used in combination with other

Skin lightening is a longstanding practice that occurs in many parts of the world. It’s been done through the use of creams, lotions, soaps, folk remedies, and staying out of the sun. The desire for light skin has been extended to children too. Advice to “marry light” is not uncommon in Asian and black families,