Tag: promotes

Chaperone protein imbalance can play a significant role in initiating toxic accumulation of tau in the aging brain—an early step in the development of Alzheimer’s disease and related neurodegenerative disorders known as tauopathies, a new preclinical study by University of South Florida Health (USF Health) neuroscientists suggests. In humans, misfolding of the protein tau leads

Scientists from Nanjing University and the University of Macau have devised a new approach to extend the survival of transplanted probiotics in vivo, enhancing the efficacy of cancer chemo-/immunotherapies in mice. The paper entitled “smectite promotes probiotic biofilm formation in the gut for cancer immunotherapy,” appears online today in Cell Reports. The gut contains trillions

Immunotherapy is one of the most promising approaches to inhibit tumor growth and metastasis by activating host immune functions. However, so far, immunotherapy still exhibits limitations of efficacy and safety, such as huge individual differences in treatment responses, difficulty to work on solid tumors, systemic immune storm and other immunotoxicity. Therefore, the development of advanced

Using cells from human breast cancers and mouse breast cancer models, researchers at the Johns Hopkins Kimmel Cancer Center say they have significant new evidence that tumor cells exposed to low-oxygen conditions have an advantage when it comes to invading and surviving in the bloodstream. The experiments mapping the “fate” of the cells in two-

Evening Sport really to insomnia? Always it is recommended, before going to bed not too much effort, and being able to exercise because you sleep this bad. However, only a few weeks ago, a study was published which came to the result that in the evening sports reduces the quality of sleep. But what is

An article published in Experimental Biology and Medicine reports that the antiarrhythmic drug, dronedarone, promotes cardiac repair after a heart attack. The study, led by Dr. Uwe Lendeckel, Professor for Medical Biochemistry and Molecular Biology at the University Medicine Greifswald, provides mechanistic explanations for the reduced infarct size that has been observed in response to

To help prevent possible complications such as nonunion at large fracture sites, researchers have developed a cartilage matrix that mimics the early stages of repair and provides the essential structural and biological properties needed by bone-forming cells to divide and grow. A new study describing the methods used for matrix decellularization and optimization to promote

Stroke is the most common cause of adult disability. This is due not only to the high incidence of stroke, but also because spontaneous recovery is often incomplete and no drugs are available that hasten recovery. Mesencephalic astrocyte-derived neurotrophic factor MANF is neuroprotective when administered before experimental stroke in rats. A massive immune response mediated