Future cardiac outcomes can be predicted by signs of cardiac stress that appear in the blood in response to exercise, Emory cardiologists report. The results were published Wed Dec 4 in JAMA Cardiology. Identifying patients with otherwise stable coronary artery disease (CAD) who are high-risk and would benefit from more intense or invasive interventions is
A combination of heart cells derived from human stem cells could be the answer to developing a desperately-needed treatment for heart failure, according to new research part-funded by the British Heart Foundation (BHF) and published in Nature Biotechnology. Researchers have found that, by transplanting an area of damaged tissue with a combination of both heart
Cancer drugs are able to halt life-threatening bacterial lung infections in mouse models by promoting lung repair, researchers at Duke Health have found. Reporting in this week’s Proceedings of the National Academy of Sciences, the research team said that if the findings are confirmed in human studies, the drugs could point to a new weapon
A number of patients who suffer from asthma are bringing their condition under control, increasing their lung function and decreasing the frequency of asthma attacks—all without going to the doctor’s office. The patients involved in a URI College of Nursing professor’s study are benefitting from an emerging trend among nurses to increase patient care by
Scientists have revealed the intricate process that bone cells use to repair themselves after mechanical injury, according to a study in the open-access journal eLife. The research provides new insight on how the body adapts to all kinds of mechanical stresses—from pressure placed on bones during simple walking, to extreme forces experienced during intense exercise.
First-of-its-kind device can repair damaged nerves – before it DISAPPEARS inside the body Scientists have created a tiny biodegradable nerve stimulator The nickel-sized device is made of silicone, magnesium, and a similar polymer to the material dissolvable stitches are made from It successfully repaired nerves in injured rats Researchers at Northwestern University and the University
An article published in Experimental Biology and Medicine reports that the antiarrhythmic drug, dronedarone, promotes cardiac repair after a heart attack. The study, led by Dr. Uwe Lendeckel, Professor for Medical Biochemistry and Molecular Biology at the University Medicine Greifswald, provides mechanistic explanations for the reduced infarct size that has been observed in response to
People whose knees have been affected by osteoarthritis, also known as the ‘wear and tear’ arthritis, often have to get knee implants to repair the damage. But if a knee implant does not fit the specific individual, it can lead to soft tissue damage, collapsing of the underlying bone, loosening of the implant and an
Proteins commonly known as BRCA—short for BReast CAncer susceptibility gene- serve a critical role in cellular DNA repair, but when mutated they allow genetic errors to replicate, facilitating cancer development. If the BRCA repair system is disabled in cancer cells, the cells simply turn to backup repair mechanisms and adapt to alternative repair pathways, a
Writing in the June 1 issue of Cell Stem Cell, researchers at University of California San Diego School of Medicine report that a first-in-human phase I clinical trial in which neural stem cells were transplanted into participants with chronic spinal cord injuries produced measurable improvement in three of four subjects, with no serious adverse effects.
DNA is the warehouse of genetic information in each living cell, and its integrity and stability are essential to life. This stability and integrity is maintained by DNA damage repair machinery. In a study published in Clinical Cancer Research, a research team at Baylor College of Medicine found that defects in selective DNA damage repair
(HealthDay)—A three-dimensional (3-D)-printed short-segment template prototype is feasible for management of complex mandibular fractures, according to a study published online April 26 in JAMA Facial Plastic Surgery. Parul Sinha, M.B.B.S., from the Washington University School of Medicine in St. Louis, and colleagues conducted a feasibility study using maxillofacial computed tomography data of three patients with
Novel stem-cell technology developed at Swinburne will be used to grow the massive number of stem cells required for a new hand-held 3-D printer that will enable surgeons to create patient-specific bone and cartilage. The technology, called BioSphere, is being developed in collaboration with St Vincent’s Hospital in Melbourne to support the development of Biopen.