Tag: research

Rates of prolonged visits for pediatric mental health emergency department (ED) visits increased over a decade, in contrast to non-mental health visits for which visit times remained stable, according to a study published in the journal Pediatrics. From 2005-2015, rates of ED visits lasting over six hours for children presenting for mental health issues jumped

Findings A UCLA research team has shown that using a truncated form of the CD4 molecule as part of a gene therapy to combat HIV yielded superior and longer-lasting results in mouse models than previous similar therapies using the CD4 molecule. This new approach to CAR T gene therapy — a type of immunotherapy that

Scientists have reported that in most cases, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic, mildly infects infants. However, around 10% of infants experienced severe COVID-19 infection who required advanced medical treatments. In rare cases, even asymptomatic infection can result in Multisystem Inflammatory Syndrome in

Scientists have reported that in most cases, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic, mildly infects infants. However, around 10% of infants experienced severe COVID-19 infection who required advanced medical treatments. In rare cases, even asymptomatic infection can result in Multisystem Inflammatory Syndrome in

Telehealth has become a critical way for doctors to still provide health care while minimizing in-person contact during COVID-19. But with phone or Zoom appointments, it's harder for doctors to get important vital signs from a patient, such as their pulse or respiration rate, in real time. A University of Washington-led team has developed a

A team of New Jersey researchers has shown that changes in perceptual certainty and response bias, two central metrics of signal detection theory (SDT), correlate with changes in cognitive fatigue. They also show that SDT measures change as a function of changes in brain activation. This finding was reported in Frontiers in Psychology on January

A team of researchers has sought to mitigate the mental health impacts of COVID-19 on adolescents by harnessing previous research on youth physical and mental health. Their review also drew on the psychological stressors of the 2011 Great East Japan Earthquake and Tsunami on children. The results were published in the Tohoku Journal of Experimental

Scientists at UC San Francisco, UC Berkeley and UCLA have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patient's own blood-forming stem cells. The trial will combine CRISPR technology developed at Innovative Genomics

Anabolic-androgenic steroids (AAS), a synthetic version of the male sex hormone testosterone, are sometimes used as a medical treatment for hormone imbalance. But the vast majority of AAS is used to enhance athletic performance or build muscle because when paired with strength training. AAS use increases muscle mass and strength, and its use is known

A study has found that a new 'care bundle' can reduce the incidence of facial pressure injuries in frontline COVID-19 healthcare workers caused by the prolonged wearing of Personal Protective Equipment (PPE). The study, led by researchers from RCSI University of Medicine and Health Sciences Skin Wounds and Trauma (SWaT) Research Centre, is published in

Tobacco smoke-exposed children utilize emergency and urgent care services more often than unexposed children, which contributes to a large toll on the nation's health care system, says research led by the University of Cincinnati. The study, recently published in the journal PLOS ONE, concluded: Children who are exposed to tobacco smoke have higher pediatric emergency

Most people with cancer who are infected by the novel coronavirus produce antibodies at a rate comparable to the rest of the population–but their ability to do so depends on their type of cancer and the treatments they've received, according to a new study by researchers at Montefiore Health System and Albert Einstein College of

New research from the University of Minnesota Medical School suggests that disease-driving B cells, a white blood cell, play a role in the development of non-alcoholic fatty liver disease (NAFLD) – the most common chronic liver condition in the U.S. Their findings could lead to targeted therapies for NAFLD, which currently affects a quarter of

Six months after it was controversially hailed by Trump administration officials as a "breakthrough" therapy to fight the worst effects of Covid-19, convalescent plasma appears to be on the ropes. The treatment that infuses blood plasma from recovered Covid patients into people newly infected in hopes of boosting their immune response has not lived up

Millions of children weighing less than 15kg are currently denied access to Ivermectin treatment due to insufficient safety data being available to support a change to the current label indication. The WorldWide Antimalarial Resistance Network (WWARN)'s new meta-analysis published today provides evidence that supports removing this barrier and improving treatment equity. A systematic review and

A groundbreaking new study led by University of Minnesota Twin Cities researchers from both the College of Science and Engineering and the Medical School shows for the first time that lab-created heart valves implanted in young lambs for a year were capable of growth within the recipient. The valves also showed reduced calcification and improved

Music-based interventions have become a core ingredient of effective neurorehabilitation in the past 20 years thanks to the growing body of knowledge. In this theme issue of Neurorehabilitation, experts in the field highlight some of the current critical gaps in clinical applications that have been less thoroughly investigated, such as post-stroke cognition, traumatic brain injury,

The vast majority of people infected with SARS-CoV-2 clear the virus, but those with compromised immunity—such as individuals receiving immune-suppressive drugs for autoimmune diseases—can become chronically infected. As a result, their weakened immune defenses continue to attack the virus without being able to eradicate it fully. This physiological tug-of-war between human host and pathogen offers

Danjuma Adda, a Nigerian public health expert, became the president-elect of the World Hepatitis Alliance (WHA) in November last year. He is the first African to hold the position. Having been infected and lost his mother to hepatitis B, Adda's personal experience has fueled his passion and drive for a paradigm shift in fighting the

Drs. Dimitrios Karamichos and Melissa Petersen at The University of North Texas Health Science Center at Fort Worth, are teaming with DownSyndrome Achieves (DSA) Biobank in Ohio to find clues about Keratoconus Dystrophy. Their research will help better identify individuals with Down syndrome who are at risk of the disease and whether this disease can