Tag: resistance

Antibiotic resistance outwitted by supercomputers

Scientists may have made a giant leap in fighting the biggest threat to human health by using supercomputing to keep pace with the impressive ability of diseases to evolve. A new study by an international team, co-led by Dr. Gerhard Koenig from the University of Portsmouth, tackled the problem of antibiotic resistance by redesigning existing

Platinum resistance in gynecologic malignancies: Response and overall survival predicted by biochemical signature

Investigators at Nagourney Cancer Institute in collaboration with colleagues at the Federal University of Sao Paulo, Brazil, University of California, Irvine and Todd Cancer Institute reported today in a paper published by Gynecologic Oncology that metabolic signatures found in the blood of gynecologic cancer patients can identify those at the highest risk of relapse. The

Resistance to antimalarial drugs measured, mapped across Africa

Despite major progress in the global fight to end malaria, the parasite responsible for the disease has evolved resistance to every antimalarial drug deployed to date. Experts have long worried about the emergence of drug resistance to the current frontline treatment in Africa, a region that accounts for the overwhelming majority of malaria cases and

Rates of macrolide resistance in S. pneumoniae high across the U.S.

(HealthDay)—There are high rates of macrolide-resistant Streptococcus pneumoniae throughout the United States, according to a study published online Feb. 4 in Open Forum Infectious Diseases. Vikas Gupta, Pharm.D., from Becton, Dickinson and Company (BD) in Franklin Lakes, New Jersey, and colleagues used the BD Insights Research Database to identify 3,626 patients with a positive S.

Could SARS-CoV-2 evolve resistance to COVID-19 vaccines?

Similar to bacteria evolving resistance to antibiotics, viruses can evolve resistance to vaccines, and the evolution of SARS-CoV-2 could undermine the effectiveness of vaccines that are currently under development, according to a paper published November 9 in the open-access journal PLOS Biology by David Kennedy and Andrew Read from Pennsylvania State University, U.S. The authors

Green tea could hold the key to reducing antibiotic resistance

Scientists at the University of Surrey have discovered that a natural antioxidant commonly found in green tea can help eliminate antibiotic resistant bacteria. The study, published in the Journal of Medical Microbiology, found that epigallocatechin (EGCG) can restore the activity of aztreonam, an antibiotic commonly used to treat infections caused by the bacterial pathogen Pseudomonas

How animal research is helping fight antibiotic resistance

People do not expect to die from a simple infection. But that might change: the world is running out of effective antibiotics. For decades, diseases like bacterial gastroenteritis and colitis have not been a serious health threat, thanks to antibiotics. These small molecules are able to kill bacteria or stop them from reproducing and spreading

Gene-targeted cancer drugs, slow release overcome resistance

Biomedical engineers at Duke University have developed a method to address failures in a promising anti-cancer drug, bringing together tools from genome engineering, protein engineering and biomaterials science to improve the efficacy, accuracy and longevity of certain cancer therapies. Using a combination of CRISPR-based targeting, a protein “depot” that allows for sustained release of the

Resistance can spread even without the use of antibiotics

Antibiotic resistance does not spread only where and when antibiotics are used in large quantities, ETH researchers conclude from laboratory experiments. Reducing antibiotic use alone is therefore not sufficient to curtail resistance, and should be done in conjunction with measures to prevent infection with resistant germs. Bacteria are becoming increasingly resistant to common antibiotics. Often,

Cranberry extract makes the bacteria more susceptible to antibiotics

Interaction between cranberry and bacteria discovered The large-fruited cranberry is better known under its English name of Cranberry. The relatives of the blueberry and cranberry contains plenty of vitamins and minerals. The berry is said to have a healing effect on urinary tract infections. The scientific evidence was lacking to date. Now a canadian research

Does insulin resistance cause fibromyalgia?

Researchers led by a team from The University of Texas Medical Branch at Galveston were able to dramatically reduce the pain of fibromyalgia patients with medication that targeted insulin resistance. This discovery could dramatically alter the way that chronic pain can be identified and managed. Dr. Miguel Pappolla, UTMB professor of neurology, said that although

Gonorrhoea: Drug resistance compromises recommended treatment in Europe

Gonorrhoea is the second most commonly notified sexually transmitted infection across the EU/EEA countries with almost 500 000 reported cases between 2007 and 2016. The infection is treatable but Neisseria gonorrhoeae keep showing high levels of azithromycin resistance according to latest results of the European Gonococcal Antimicrobial Surveillance Programme. This antibiotic agent is part of

15 Exercises Anyone Can Do at Home With Resistance Bands

Let’s face it. Sometimes, the idea of going to the gym and lifting weights doesn’t sound appealing. But what if you want to exercise and stay fit, just not at the gym? We have two words for you: resistance bands.  Resistance bands, or exercise bands, are elastic bands that come in a variety of sizes,

Operations become life-threatening due to resistance to antibiotics

Common operations including caesarean sections and hip replacements could become LETHAL due to growing resistance to antibiotics, health officials warn Public Health England said cases of antibiotic-resistant blood infections on rise Crisis is getting worse amid growing concerns that drugs are losing their power Figures revealed there were 16,504 cases where antibiotics didn’t work last

Commonly-prescribed antidepressant may be behind antibiotic resistance

Prozac may be driving the antibiotic-resistance crisis Commonly-prescribed antidepressant Prozac may be driving the antibiotic-resistance crisis E.coli undergoes genetic mutations when exposed to the antidepressant Up to 11% of the antidepressant passes through a person’s body into sewers Experts have warned antibiotic resistance poses ‘as big a risk as terrorism’ e-mail 1 View comments The

Soaps and toothpastes may be behind the antibiotic-resistance crisis

Are toothpaste and SOAP making you resistant to antibiotics? Chemical in everyday toiletry stops infections responding to drugs Chemical triclosan is found in many everyday hygiene products It has previously been linked to reduced heart health and an underactive thyroid Experts have warned antibiotic resistance poses ‘as big a risk as terrorism’ It is thought to

Study identifies a link between antidepressant treatment resistance and inflammation

Researchers at Emory University have found that depressed patients who have not responded to multiple antidepressants exhibit evidence of increased inflammation. Findings were recently published online in the journal, Psychoneuroendocrinology. The study shows that antidepressant treatment resistance is associated with increased inflammatory markers in patients with depression. One third of patients with depression fail to