A hospital outbreak of carbapenem-resistant Enterobacteriaceae (CRE) became more worrisome when researchers found resistance genes being shared among unrelated bacteria via plasmids and other mobile genetic elements. This new research will be presented at ASM Microbe, the annual meeting of the American Society for Microbiology, held from June 7th through June 11th in Atlanta, Georgia.
DNA is the warehouse of genetic information in each living cell, and its integrity and stability are essential to life. This stability and integrity is maintained by DNA damage repair machinery. In a study published in Clinical Cancer Research, a research team at Baylor College of Medicine found that defects in selective DNA damage repair
In response to antibiotics, a gene regulation network found in the bacterium Acinetobacter baumannii acts to boost both virulence and antibiotic resistance. Edward Geisinger of Tufts University School of Medicine and colleagues present new insights into this system in a study published in PLOS Pathogens. A. baumannii is a multi-drug resistant bacterium that spreads in
Although allergies affect more than 50 million Americans, they are occasionally misunderstood and can be seen as a minor condition. An article published in Annals of Allergy, Asthma and Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI) shows allergies can have serious, far-reaching consequences, especially on adolescent sufferers. “The
Growing levels of resistance to antifungal treatments could lead to increased disease outbreaks and affect food security around the world. An international team, led by researchers from Imperial College London and the University of Exeter, warns that improvements are needed in how existing drugs are used, as well as an increased focus on the discovery
(HealthDay)—Resistance exercise training (RET) is associated with reduced depressive symptoms among adults, according to a meta-analysis published online May 9 in JAMA Psychiatry. Brett R. Gordon, from the University of Limerick in Ireland, and colleagues examined the correlation of efficacy of RET with depressive symptoms using data from 33 randomized clinical trials involving 1,877 participants.
A multi-institutional research team has identified what may be a novel mechanism underlying acquired resistance to CDK 4/6 inhibitor treatment for breast cancer. In their report published in the Annals of Oncology, the team—led by investigators at Massachusetts General Hospital (MGH), Institute Gustave Roussy in Paris, and Texas Oncology-Baylor Sammons Cancer Center/U.S. Oncology in Dallas—reports
Infection specialists at hospitals are introducing so-called antimicrobial stewardship (AMS) programmes to use antimicrobial drug therapies more responsibly. Such programmes include a coherent set of actions which promote using antimicrobials in ways that ensure sustainable access to effective therapy for all who need them. A group of international experts, led by researchers from the Center
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