A lung transplant can mean the difference between life and death for people with diseases such as pulmonary fibrosis, chronic obstructive pulmonary disease (COPD) and even severe COVID-19. Yet, recipients of donor lungs must take daily medications to stave off damage caused by their own immune system, which attacks the organs it recognizes as foreign—a
A KAIST immunology research team found that a specific subtype of macrophages that originated from blood monocytes plays a key role in the hyper-inflammatory response in SARS-CoV-2 infected lungs, by performing single-cell RNA sequencing of bronchoalveolar lavage fluid cells. This study provides new insights for understanding dynamic changes in immune responses to COVID-19. In the
(HealthDay)—Primary care physicians have been the largest provider of vaccinations for older individuals, according to a study published online in the July 1 issue of the Annals of Family Medicine. Elizabeth Wilkinson, from the Robert Graham Center for Policy Studies in Family Medicine and Primary Care in Washington, D.C., and colleagues used 2017 Medicare Part
As integral members of stroke treatment teams, nurses coordinate patient assessment and collaborate care among multiple health care professionals to facilitate the best possible outcomes for patients with acute ischemic stroke. Nurses also advocate for patients and their caregivers to ensure they receive appropriate information and education to successfully navigate phases of treatment in the
Just as a small airport would have challenges handling massive plane traffic, people with psychosis may experience communication difficulties because non-language parts of the brain are trying to manage communications tasks, new research from Western and Lawson Health Research Institute shows. Difficulties with communication—the ability to use language and to comprehend what others are saying—are
For many years, neuroscientists worldwide have been trying to understand the neural and cognitive processes underpinning artistic expression. While past findings have identified a number of brain areas that could be associated with the creation of different forms of art, scientists have yet to attain a full and comprehensive picture of the neural processes behind
The designated driver (DD) is a successful public health strategy dating back to the late 1980s. To better reflect the realities of today’s society, now is a good time to evolve the initiative to help mitigate the harms tied to broader substance use and beyond drinking and driving. The promotion of “buddy circles,” as an
Prolonged sleep deprivation can lead to severe health problems in humans and other animals. But why is sleep so vital to our health? A UCLA-led team of scientists has answered this question and shown for the first time that a dramatic change in the purpose of sleep occurs at the age of about 2-and-a-half. Before
Beta-1 integrin, a critical component of epithelial extracellular matrix receptors, is essential for normal lung function in adulthood, researchers at Vanderbilt University Medical Center have discovered. In a mouse model, deleting the gene for beta-1 integrin from the epithelial cells lining the alveoli of the adult lung, where the exchange of oxygen and carbon dioxide
New findings by a University of Houston psychology professor indicate that among firefighters, distress tolerance amplifies associations between posttraumatic stress disorder (PTSD) symptoms and alcohol use severity. In the world of psychology, distress tolerance is your actual or perceived ability to withstand emotional distress. It is surviving—and knowing you can survive—an emotional incident. “Firefighters who
A new American Cancer Society study links health insurance literacy with medical financial hardship as well as non-medical financial sacrifices among adult cancer survivors in the United States. The authors say the study indicates that health insurance literacy may be an important intervention for addressing financial problems associated with cancer. The report appears in JNCI
The maturation of skin microbial communities during childhood is important for the skin health of children and development of the immune system into adulthood, but only a few studies have analyzed the microbiota in young children. In a new study, investigators in China found that bacterial genera in children were more similar to those of
Researchers have long-known that abused children are at higher risk of adolescent drug use. But a new study shows that having a father in the picture serves as a “protective factor,” helping to mitigate early childhood trauma. Researchers from the Jack, Joseph, and Morton Mandel School of Applied Social Sciences at Case Western Reserve University,
A team of Florida State University researchers used a simple tumor model to show the importance of tissue microenvironment in primary tumor formation. In the journal Developmental Cell, FSU researchers explain how certain signaling pathways define tumor hotspots, tissue microenvironment favorable for tumorigenesis, and show that simple stimulation of a protein can lead directly to
The results of a recent Texas A&M University-led study provide insights into the mechanism by which estrogen can decrease insulin resistance and the production of glucose, reducing incidences of Type 2 diabetes mellitus. The study, “Estrogen Improves Insulin Sensitivity and Suppresses Gluconeogenesis via the Transcription Factor Foxo1,” can be found online in the Diabetes journal
FRIDAY, Feb. 1, 2019 — Forests are changing in ways that could mean they emit more gases that contribute to smog, acid rain and respiratory problems, a new study suggests. “This study has profound implications for future air quality. Human activities, such as fire suppression, fertilizer use and climate change, are causing forest populations to
Astrocytes—the star-shaped cells of our brain—are very busy. Their job description includes maintaining the blood-brain barrier, removing excess neurotransmitters, repairing brain tissue and more. Their important role in brain function suggests astrocytes are also involved in disease. Scientists are particularly interested in uncovering how they may drive inflammation in the brain. Brain inflammation is linked
Researchers at the Kavli Institute for Systems Neuroscience in Norway have discovered a network of brain cells that expresses our sense of time within experiences and memories. “This network provides timestamps for events and keeps track of the order of events within an experience,” says Professor Edvard Moser, Nobel laureate and director of the Kavli
Researchers have long believed that the amygdala, an almond-shaped structure in the brain, is central to the experience and perception of fear. Studies initiated in the 1990s of a patient with a rare condition affecting the amygdala initially seemed to support this conclusion. However, as Lisa Feldman Barrett, Ph.D., of the Massachusetts General Hospital (MGH)
Being aware of our surroundings is a fundamental aspect of our existence. But what in our biological makeup determines how we access and interpret the endless stream of information around us? A new Tel Aviv University study published in Current Biology suggests that noradrenaline, a neurotransmitter responsible for arousal in the brain, plays a vital
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