Tag: Skin Cancer

By incorporating a gene-suppressing drug into an over-the-counter gel, researchers at Albert Einstein College of Medicine and their colleagues cut healing time by half and significantly improved healing outcomes compared to control treatments. Results from the combination therapy, which was tested in mice, were published online today in Advances in Wound Care. “Not only did

Researchers have discovered a novel consequence of loss of the tumour protein p53 that promotes cancer development, according to new findings in eLife. The study in mouse and human cells, from the Netherlands Cancer Institute, suggests that multiplication of cancer cells in the absence of appropriate growth stimuli is supported by the additional loss of

There are more than 200 bones in the human body. Bone is formed during embryonic and postnatal skeletogenesis by two distinct, well-organized processes, intramembranous and endochondral ossification. Mesenchymal stem cells differentiate into chondrocytes to form a cartilaginous template, which, for long bones, induces bone formation through endochondral ossification. Extracellular signal-regulated kinase 5 (Erk5), which is

A new cell culture platform allows researchers to observe never-before-seen behaviors of live cancer cells under the microscope, leading to explanations of long-known cancer characteristics. The easy-to-produce platform developed by Hokkaido University researchers offers cancer cells micro-scale attachment sites that elicit never-before-seen behaviors highly relevant to cancer’s clinical properties. The observation of these behaviors shed

A team of Hokkaido University scientists studied the molecules involved in mitochondrial movements within highly invasive breast cancer cells. They identified a pathway that ultimately leads to the dispersion of these energy-generating organelles towards the cells’ periphery, increasing cancer invasiveness. When this pathway was blocked, mitochondria aggregated within the cell’s center, where they started overproducing

When it comes to transplant rejection, some organs are far trickier than others. Some transplantable organs, such as the liver, are readily accepted by the recipient’s immune system, rarely triggering an immune response and rejection. But the skin is a very different matter: Skin grafts have a high rate of rejection for unknown reasons. Investigators

“Lego block” artificial cells that can kill bacteria have been created by researchers at the University of California, Davis Department of Biomedical Engineering. The work is reported Aug. 29 in the journal ACS Applied Materials and Interfaces. “We engineered artificial cells from the bottom-up — like Lego blocks — to destroy bacteria,” said Assistant Professor

In China, people breathe air thick with the lung-damaging pollutant ozone two to six times more often than people in the United States, Europe, Japan, or South Korea, according to a new assessment. By one metric — total number of days with daily maximum average ozone values (8-hour average) greater than 70 ppb — China

A UCLA-led study has found that a treatment that uses a bacteria-like agent in combination with an immunotherapy drug could help some people with advanced melanoma, an aggressive form of skin cancer, live longer. The research showed that using the immunotherapy drug pembrolizumab and the experimental agent SD-101, a sequence of nucleic acids that mimics

The fight against cystic fibrosis (CF) has taken a major step forward, with pioneering research by University of Adelaide scientists showing that cells causing the debilitating genetic disorder could be successfully replaced with healthy ones. The research published in the journal Stem Cell Research and Therapy applies cell transplantation therapy, normally used in bone marrow

We’re all aware of the importance of wearing sunscreen at the beach. But when it comes to incorporating it into our daily skin care regime, the majority of us aren’t exactly vigilant slip slop slappers. But if this story doesn’t prove it’s time to change our ways, we don’t know what will. A photo of

A new microscope system can image living tissue in real time and in molecular detail, without any chemicals or dyes, report researchers at the University of Illinois. The system uses precisely tailored pulses of light to simultaneously image with multiple wavelengths. This enables the researchers to study concurrent processes within cells and tissue, and could

Using a targeted therapy to block a protein that suppresses T cell activity could improve cancer treatment with immune checkpoint inhibitors, researchers at The University of Texas MD Anderson Cancer Center report today in the Journal of Clinical Investigation. The team showed that EZH2 is elevated in immune T cells in patients after treatment with

One of the main risk factors for non-melanoma skin cancer (NMSC), the most common cancer worldwide, is solar ultraviolet radiation. A new Journal of the European Academy of Dermatology and Venereology study has found that different outdoor professions carry different risks for NMSC. In the study of 563 participants (47% women) consisting of 348 outdoor

Cancer cells in children tend to develop by following four main trajectories — and two of them are linked to relapse of the disease, research led by Lund University in Sweden shows. The four strategies can occur simultaneously in a single tumour, according to the study that is now published in Nature Genetics. The researchers

Is it safe to get a "base tan" in the summer? No. There is no safe amount of tanning. Tanning isn't bad for you just because it comes with the risk of burning, which can cause skin cancer. Tanning is bad for you because your body doesn't even begin to tan until dangerous ultraviolet (UV)

Good news all of you fair-skinned beauties, there’s new evidence to suggest that a higher SPF actually does work. For years, science, or more accurately, the Food and Drug Administration, has been telling us that anything higher than SPF 50 was basically useless but a recent study published in the Journal of the American Academy

With summer coming, it’s only a matter of time before the smells and tastes of barbecued foods dominate the neighborhood. But there’s a downside to grilling that can literally get under your skin. In a study appearing in Environmental Science & Technology, scientists report that skin is a more important pathway for uptake of cancer-causing

Publication in Nature Cell Biology: researchers at the Université libre de Bruxelles, ULB define for the first time the mechanisms responsible for the mammary gland development. The mammary gland is the tissue that produces the milk during lactation, allowing the survival of young mammalian offspring. The mammary gland is composed of two main lineages: the

A new study finds that one of the toughest characters in the immune system, the macrophage, has a nurturing side, at least when it comes to guarding the developing breast. The study published online this week in the journal Science found that macrophages play an important role in maintaining the mammary gland’s stem cell niche,