Researchers at The University of Texas MD Anderson Cancer Center have discovered that a protein called NF-kappa B-inducing kinase (NIK) is essential for the shift in metabolic activity that occurs with T cell activation, making it a critical factor in regulating the anti-tumor immune response. The preclinical research, published today in Nature Immunology, suggests that
(HealthDay)—America’s roads are notoriously unsafe on New Year’s Eve, and a new study shows that marijuana legalization could be making the situation even worse. Almost half of teenagers who regularly use pot admit they’ve gotten behind the wheel while stoned, a new study in JAMA Network Open reveals. Overall, twice as many teens report driving
One of the physiopathological characteristics of Covid-19 that has most baffled the scientific and medical community is what is known as “silent hypoxemia” or “happy hypoxia”. A recent study sheds light on the explanation for the lack of blood oxygenation detected in many Covid-19 patients. The study was published in the journal function. Patients suffering
People in Scotland’s poorest areas are more likely to be affected by severe COVID-19—and to die from the disease—than those in more affluent districts, according to a study of critical care units. The first nationwide study of its kind found patients from the most economically disadvantaged areas had a higher chance of critical care admission,
MONDAY, Dec. 14, 2020 — Having depression during childhood or in the teen years appears to increase the odds of illness and early death later on, researchers say. The new long-term study included nearly 1.5 million Swedes. Of those, more than 37,000 were diagnosed with depression at least once between the ages of 5 and
Preschool children’s eating, activity, and sleep routines were disrupted during the spring COVID-19 lockdown, which may be detrimental to child health and development a study suggests. Parents of children (aged three- to five-year-old) due to start school in September 2020 shared their children’s experiences of the spring lockdown with academics from the Universities of Bristol,
Adipose tissue is not just a simple reservoir of energy for periods of food scarcity. It contributes significantly to regulation of the metabolism, releasing various molecules into the bloodstream, including microRNAs that modulate the expression of key genes in different parts of the organism, including the liver, pancreas, and muscles. Research has shown that both
In recent years, targeted therapies have cemented their place as some of the most important tools in cancer treatment. These medicines are designed to block specific signals that tumor cells use to grow and spread, while at the same time leaving normal cells unharmed. Targeted therapies can significantly extend patients’ lives, but the benefits are
A study led by researchers from the Boston University School of Public Health (BUSPH) claims that Medicaid expansion is not enough to improve the health care for patients with diabetes. According to a study published in the American Journal of Preventive Medicine, the Medicaid expansion which has insured improved healthcare facilities to millions of patients
Fiji’s national vaccine program against pneumonia, a serious lung condition, and rotavirus, a common disease which causes severe diarrhoea and vomiting, has reduced illness and death, new research shows. The University of Melbourne-led research team, which worked with the Fiji Ministry of Health and Medical Services, says the results underline the importance of vaccines and
Even before the pandemic and the presidential election, Americans reported some of the highest perceived levels of stress in the world, according to the American Psychological Association. Not only does stress have negative effects on work and personal relationships, it also increases the risk of many chronic conditions, such as heart disease and Alzheimer’s disease,
A new national survey, looking at how the COVID-19 pandemic has impacted young US adults’ loneliness, reveals “significant depressive symptoms” in 80% of participants. Over 1,000 Americans aged 18-35 took part in the online anonymous questionnaire, which also asked the subjects to report on their anxiety and substance use. The analyzed findings, published in the
Studies from a randomised controlled trial reveals the capability of walnuts from preventing major risk factors for heart disease, claims,’ people who regularly consume walnuts may have a lower risk of heart disease, compared to those who do not eat’. In the study, conducted by Dr Emilio Ros from the Hospital Clinic of Barcelona, in
Scientists have found that insulin has met an evolutionary cul-de-sac, limiting its ability to adapt to obesity and thereby rendering most people vulnerable to Type 2 diabetes. A recent study from scientists at Indiana University School of Medicine, the University of Michigan and Case Western Reserve University has determined that the sequence of insulin has
Subjective wellbeing leads to better health, but we did not know what in our younger years determines our wellbeing in old age. Researchers at the Tokyo Metropolitan Institute of Medical Science have demonstrated that adolescents who valued their interests and curiosity had higher wellbeing in old age from a 60-year-old cohort in the UK. We
Providing support to help people with prediabetes make small changes to their lifestyle, diet and physical activity can almost halve the risk of developing type 2 diabetes, according the results of the Norfolk Diabetes Prevention Study (NDPS) the largest diabetes prevention research study in the world in the last 30 years. The findings of the
Recent study by Estonian researchers at the University of Tartu explains how coronavirus is activated before attacking cells and what could help to impede that. The study, published in Scientific Reports, takes us a step closer to understanding why the spread of SARS-CoV-2 has been so rapid and aggressive. The studied virus activation mechanism is
A statistical estimation technique developed by a University of Notre Dame researcher offers public health officials a new way to build short-term forecasts of coronavirus diagnoses and deaths. It also provides additional insight into the effectiveness of earlier pandemic mitigation measures in 30 countries. As the COVID-19 pandemic began to spread globally in early 2020,
As people age, they often lose their motivation to learn new things or engage in everyday activities. In a study of mice, MIT neuroscientists have now identified a brain circuit that is critical for maintaining this kind of motivation. This circuit is particularly important for learning to make decisions that require evaluating the cost and
Findings from a new study conducted by a team of researchers at Dartmouth’s Geisel School of Medicine and published in the journal Preventive Medicine Reports, show that involving pediatric practices in the promotion of private well water testing can influence parental compliance. More than 43 million people living in primarily rural areas of the U.S.
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