Tag: system

Emergency room patients who were flagged by an artificial-intelligence algorithm for possibly having sepsis received antibiotics sooner and had better outcomes, according to a peer-reviewed study conducted by physician-researchers at Case Western Reserve University and MetroHealth. Their findings were published in the journal Critical Care Medicine. “We showed that when providers had access to the

In a new study published in the Cell Research, Chen-Yu Zhang’s group at Nanjing University reports “In vivo self-assembled small RNA is the new generation of RNAi therapeutics.” The development of RNAi therapy has undergone two major stages, direct injection of synthetic siRNAs and delivery with artificial vehicles; neither have realized the full therapeutic potential

Vitamins and supplements are highly useful tools for a lot of folks looking for some immune system support through cold and flu season and beyond. But they are just that—tools. They are not a foolproof solution to stay healthy. The best way to achieve that goal, and support a strong immune system, is by packing

Children are protected from severe COVID-19 because their innate immune system is quick to attack the virus, a new study has found. The research led by the Murdoch Children’s Research Institute (MCRI) and published in Nature Communications, found that specialized cells in a child’s immune system rapidly target the new coronavirus (SARS-CoV-2). MCRI’s Dr. Melanie

At the time of writing, coronavirus disease 2019 (COVID-19) is seriously threatening human lives and health throughout the world. Before effective vaccines and specific drugs are developed, non-pharmacological interventions and numerical model predictions are essential. To this end, a group led by Professor Jianping Huang from Lanzhou University, China, developed the Global Prediction System of

Scientists at the University of Wisconsin School of Medicine and Public Health are breaking new ground to make cancer cells more susceptible to attack by the body’s own immune system. Working in mice, a team led by Jamey Weichert, professor of radiology, and Zachary Morris, professor of human oncology, is combining two different techniques in

Cancers sometimes escape our immune defenses because of the over-activity of molecular signaling systems, called checkpoint processes. Now we may be able to fight back using a new range of molecules, researchers in China report in the European Journal of Medicinal Chemistry. “We have been working on the discovery of anti-cancer agents for more than

The gut is an unusually noisy place, where hundreds of species of bacteria live alongside whatever microbes happen to have hitched a ride in on your lunch. Scientists have long suspected that the gut’s immune system, in the face of so many stimuli, takes an uncharacteristically blunt approach to population control and protection from foreign

A Rutgers-led team has created a smart drug delivery system that reduces inflammation in damaged nervous tissues and may help treat spinal cord injuries and other neurological disorders. The system, which uses extremely thin biomaterials implanted in the body, also protects nerve fibers (axons) that connect nerve cells in injured neural tissues, according to a

Tousled-like kinases (TLKs) are a potential therapeutic target for cancer treatment due to their central role in DNA repair and replication. The latest work by IRB Barcelona’s Genomic Instability and Cancer Laboratory, led by Travis H. Stracker, concludes that TLK inhibition activates the innate immune system, a very important factor in the response to cancer.

In a recent article published in the February issue of the journal Sensors, researchers at Texas A&M University have reported a technology that might help people with gout disease monitor their symptoms better. They said their minimally invasive biosensor system may hold the key to future point-of-care therapies centered around personal management of gout, and

When it comes to memory, immune cells are known as the “bad cops” of the brain. But new research shows they could also be turned into “good cops” to power memory and learning. Inflammation can send the brain’s immune cells into damaging hyperdrive, and this has been linked to neurodegenerative diseases that affect memory, like

Digestion is the process of digesting food. Through a series of chemical reactions, the body breaks food down into smaller particles to aid the absorption of nutrients into the bloodstream. The complete process of digestion takes 24 to 72 hours. The exact time is dependent on several factors, including the presence of digestive issues and

NHS could free hospital beds and ‘save lives’ using AI which tells doctors when patients are stable enough to go home up to THREE DAYS earlier The system by a patients’ bedside collects data on their vitals  It builds a picture of their condition and gives a score from zero to 20  Patients were able

Children and adolescents detained in the youth justice system experience poor health across a range of physical and mental health domains, according to new research. In the first global review, researchers from the University of Melbourne, Murdoch Children’s Research Institute (MCRI) and University of Sheffield in the UK have examined the health of detained adolescents

Researchers have cleared a major obstacle in the development of an HIV vaccine, proving in animal models that effective, yet short-lasting antibodies can be coaxed into multiplying as a fighting force against the virus. The finding, led by a team of researchers at the Duke Human Vaccine Institute (DHVI) and Boston Children’s Hospital, publishes online

Individuals who experience an unpleasant tingling in their hands or feet or who suffer from painful discomfort and numbness could be affected by a neuropathy—a disorder of the nervous system in which the nerve fibers become damaged and may begin to degenerate. This effect is already visible on the cornea before the first symptoms appear.

Dear Mayo Clinic: I am 72 and take a drug for rheumatoid arthritis that suppresses my immune system. I’m scheduled to receive a vaccine later this year. Is it safe for me to receive this vaccine? A: Appropriate and timely vaccines are important for anyone with a suppressed immune system. That’s because a suppressed immune

When immune cells detect harmful pathogens or cancer, they mobilise and coordinate a competent defence response. To do this effectively immune cells must communicate in a way that is tailored to the pathogenic insult. Consequently, the body’s response to various health challenges depends on successful coordination among the cells of the immune system. Key players

Getting up close—and a little dirty—with farm animals just might help us fend off illness, say researchers who’ve further demonstrated the benefits of early exposure to a wide variety of environmental bacteria. Scientists from The Ohio State University found that bacteria and other microbes from rural Amish babies was far more diverse—in a beneficial way—than