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A physician-scientist at the University of Arizona Cancer Center investigated a novel treatment for pancreatic cancer patients whose tumors exhibited a harmful genetic mutation. The results, in which a type of drug called a PARP inhibitor showed early promise in treating pancreatic cancer in patients with mutations in the BRCA gene, were published online last

Dyslexic children learning both a language that is pronounced as written, like Spanish, and a second language in which the same letter can have several sounds, such as English, are less affected by this alteration when reading or writing in the latter language. The authors a new study say that this is less a cure

The results of a study to be presented at the Annual European Congress of Rheumatology (EULAR 2018) suggest that rates of anxiety and depression in patients with rheumatoid arthritis correlate with measures of disease activity over the first year following diagnosis. Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects a person’s joints, causing

Austrian researchers have discovered that a small number of patients taking targeted drugs known as Janus kinase (JAK) inhibitors to treat myelofibrosis may develop aggressive lymphomas. They also speculate that screening for a preexisting B-cell clone before starting therapy may help prevent this side effect and potentially save lives, according to a study published online

When first learning to drive, young adults with autism spectrum disorder (ASD) have more difficulty with basic driving skills compared to those with typical development (TD), reports a study in the Journal of Developmental & Behavioral Pediatrics, the official journal of the Society for Developmental and Behavioral Pediatrics. But licensed drivers with ASD have similar

Blood flow changes in the brains of children, adolescents and young adults with chronic kidney disease may explain why many face a higher risk of cognitive impairment, according to a study published online in the journal Radiology. Prior research has linked chronic kidney disease, a condition characterized by the loss of kidney function over time,

To diagnose rheumatoid arthritis, antibodies to the amino acid citrulline are commonly measured. A new study from Uppsala University shows that a broad mix of different antibodies in the joints is the dominant factor that can be associated with severe inflammation and joint damage. These findings, published in Annals of the Rheumatic Diseases, may eventually

A new study has shown that women who gave birth as adolescents tend to have a greater chance of an early menopause or a hysterectomy. The study, which looked at reproductive histories of women from several countries and income groups, is presented at the World Congress of Menopause in Vancouver. There is increasing evidence that

A new study reveals that pediatric neuroblastoma patients are at elevated risk for long-term psychological impairment. In addition, those who experience such impairment as they get older tend to require special education services and to not go on to college. The findings are published early online in Cancer, a peer-reviewed journal of the American Cancer

New research findings from Baylor University’s Diana R. Garland School of Social Work could change the adoption landscape for birth mothers struggling with the life-altering decision to place their children. There is consensus among adoption researchers that for many birth mothers the experience of placing their children for adoption brings feelings of grief, loss, shame,

Recently published research shows that learning disabilities (LD) diagnosed in childhood are associated with adult-age mental health problems, delays or difficulties in attaining an educational degree, and unemployment. In the longitudinal study conducted by the Niilo Mäki Institute and University of Jyväskylä Finland, individuals with childhood LD (n = 439) were compared to a population-based

One in every 125 babies is born with a heart condition – but thanks to modern medicine more infants are surviving than ever before. In the developed world, 90% will now live into adulthood, compared with just 20% in the 1940s. However, there is no cure for these conditions and the person needs lifelong medical

Reversing memory deficits and impairments in spatial learning is a major goal in the field of dementia research. A lack of knowledge about cellular pathways critical to the development of dementia, however, has stood in the way of significant clinical advance. But now, researchers at the Lewis Katz School of Medicine at Temple University (LKSOM)

In a study of patients with chronic kidney disease (CKD), persistent substance use—especially of hard illicit drugs—was linked with higher risks of CKD progression and early death. The findings appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). CKD is common in the United States, and affected patients

Achieving and maintaining a healthy weight may not be easy, but it can improve a person’s health and should be a goal for people with diabetes. Some of the benefits include: better cholesterol levels improved blood pressure more stable blood sugar levels lower risk of long-term health problems In this article, we consider how people

Fewer gay and bisexual men are using condoms while taking PrEP, the antiretroviral pill that prevents HIV, according to research published today in the The Lancet medical journal. The study shows the rate of gay and bisexual men in Sydney and Melbourne taking pre-exposure prophylaxis (PrEP), and reporting condomless anal intercourse with casual partners, has

Last month, Erich Voigt, MD, an ear, nose and throat surgeon in New York, was watching TV, tuned in to HGTV’s Beachfront Bargain Hunt. But instead of checking out the tropical homes, he was drawn to show guest Nicole McGuinness. After noticing an unusual lump on the 32-year-old’s neck, he sent a Facebook message with an alarming warning.

Immunization with beneficial bacteria can have long-lasting anti-inflammatory effects on the brain, making it more resilient to the physical and behavioral effects of stress, according to new research by University of Colorado Boulder scientists. The findings, if replicated in clinical trials could ultimately lead to new probiotic-based immunizations to protect against posttraumatic stress disorder (PTSD)

Managing type 1diabetes during the first two decades of life is challenging. Insulin requirements change along with the stages of life —- childhood, puberty, young adulthood, and beyond. But a 20-year longitudinal study conducted by researchers from Joslin Diabetes Center and Harvard Medical School identifies clear predictors of rising A1C levels in young persons, as

Having a stressful job is associated with a higher risk of a heart rhythm disorder called atrial fibrillation, according to research published today in the European Journal of Preventive Cardiology, a European Society of Cardiology (ESC) journal. The most stressful jobs are psychologically demanding but give employees little control over the work situation—for example, assembly