Adding the monoclonal antibody drug trastuzumab—already used to treat certain breast cancers—to the chemotherapy regimen of women with a rare form of uterine cancer lengthens the amount of time their tumors are kept from growing, according to Johns Hopkins Medicine researchers conducting a small phase II trial of the regimen, testing its safety and value.
Patients with one or more high-risk clinical features (tearing pain, hypotension, pulse deficit, neurologic deficit, new murmur) should be considered high risk for acute aortic dissection (AAD). That is the finding of a study to be published in the April 2018 issue of Academic Emergency Medicine (AEM), a journal of the Society for Academic Emergency
Researchers from the University of Leicester have shed new light on how neurons in the brain communicate with one another. This could potentially help in our understanding of how and why a range of neurodegenerative diseases occur. The team, led by Dr Joern Steinert from the MRC Toxicology Unit at the University of Leicester, has
Testing Māori and Pacific people for an irregular heartbeat earlier could spare hundreds of people from stroke each year, a University of Auckland study has found. The research, a collaboration between University researchers and the Heart Research Institute in Sydney, reveals for the first time that Māori and Pacific people develop Atrial Fibrillation (AF) an
(HealthDay)—Pharmacists have been involved in the recent progress made toward reducing hospital-acquired infections (HAIs), according to an article published in Drug Topics. According to the latest data from the U.S. Centers for Disease Control and Prevention, between 2008 and 2016 there was a 50 percent decrease in central line-associated bloodstream infections as well as other
Scientists have long theorized that blood flow plays an integral role in cancer metastasis. But new research testing this long-held hypothesis in zebrafish and humans confirms that the circulatory blood flow impacts the position where circulating tumor cells ultimately arrest in the vasculature and exit into the body, where they can form a metastasis. In
Research led by a psychologist at the University of California, Riverside, shows that bilinguals regulate, or suppress, their native language when reading in a second language. Many in media and in science often assume that reading or speaking in a second language—one that has been learned later in life than the native or first language—is
A new study indicates that the kinds of microbes living in the gut influence the severity and recurrence of parasitic worm infections in developing countries. The findings, by researchers at Washington University School of Medicine in St. Louis, suggest that manipulating the gut’s microbial communities may protect against intestinal parasites, which affect more than 1
Michigan’s Medicaid expansion was associated with more people receiving procedures for coronary artery disease without a negative effect on patient outcomes. That’s according to a recent research letter in the Journal of the American College of Cardiology. “Relative to the 24 months prior to the April 2014 expansion, patients having coronary revascularization procedures within 24
It’s a paradox of Alzheimer’s disease: Plaques of the sticky protein amyloid beta are the most characteristic sign in the brain of the deadly neurodegenerative disease. However, many older people have such plaques in their brains but do not have dementia. The memory loss and confusion of Alzheimer’s instead is associated with tangles of a
Chronic focal encephalitis, or Rasmussen’s encephalitis, is a rare and devastating inflammatory brain disease that can lead to the destruction or removal of a part of the affected child’s brain. Through experiments on humanized mice, a team of researchers from Université de Montréal and the CHU Sainte-Justine and Université de Montréal Hospital (CHUM) research centres
Belly fat affects the odds of women surviving kidney cancer but not men, according to a new study by researchers at Washington University School of Medicine in St. Louis. Half of female kidney cancer patients with substantial abdominal fat at the time of diagnosis died within 3 1/2 years, while more than half of women
Understanding how neighborhood dynamics regulate mosquito bites is key to managing diseases like West Nile virus and Zika virus. Today in Parasites & Vectors, researchers report that in Baltimore, Maryland, socioeconomic differences between neighborhoods influence bite risk, with rats being a primary blood meal source in lower income neighborhoods. Shannon LaDeau, a disease ecologist at
More than 70 years since the end of World War II, there are still signs of intergenerational transmission of Holocaust trauma that are manifested in the way adult offspring of Holocaust survivors care for their elderly parents, according to a new study by researchers at Bar-Ilan University. To this day scholars debate whether intergenerational transmission
Crimean-Congo hemorrhagic fever (CCHF) is a viral disease spread by ticks in the Middle East, Asia, Africa and parts of Europe. Infection with CCHF virus is fatal in nearly one of every three cases. No specific treatments or vaccines for CCHF exist, primarily because a suitable animal model for studying the disease has not been
If you enjoy listening to music, a live performance is where that enjoyment will peak, according to a new study led by Western researchers. When individuals attend a live concert and listen to music as a group, their brains waves synchronize – a bond that indicates each individual is having a better time as part
People whose negative emotional responses to stress carry over to the following day are more likely to report health problems and physical limitations later in life compared with peers who are able to “let it go,” according to findings published in Psychological Science, a journal of the Association for Psychological Science. “Our research shows that
Blocking the activity of an enzyme that has a key role in the generation of recurring seizures may provide a new way to treat epilepsy that is resistant to anti-seizure drugs, according to a study of rats and mice published in JNeurosci. One-third of people with epilepsy, one of the most common neurological disorders, do
Crimean-Congo hemorrhagic fever (CCHF) is a viral disease spread by ticks in the Middle East, Asia, Africa and parts of Europe. Infection with CCHF virus is fatal in nearly one of every three cases. No specific treatments or vaccines for CCHF exist, primarily because a suitable animal model for studying the disease has not been
Inflammation is a normal part of the body’s response to infection, chronic stress or obesity. In pregnant women, it is believed that heightened inflammation increases the risk of mental illness or brain development problems in children. A study conducted by researchers at OHSU in Portland, Oregon, has established a link between inflammation in pregnant women
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