A team from the University of Oxford and Cardiff University have used mathematical models to re-enact the complex process of brain development that occurs as initialising cells, otherwise known as progenitor cells, start to grow and begin to differentiate into more specialist cells at various points in time. By applying this experimentally realistic model to
Researchers from the Novo Nordisk Foundation Center for Protein Research at the Faculty of Health and Medical Sciences have characterised a new protein that is important to the genetic stability of cells. It may be significant for the development of new drugs against genetically determined diseases like cancer, sterility and premature ageing. All cell nuclei
For a while, it looked like 2018 was going to be the year of rosé cider, with new releases from Angry Orchard, Crispin and Strongbow, just to name a few. But spiked rosé seltzer might just become the pink drink of the summer with Smirnoff’s release of Raspberry Rosé Spiked Sparkling Seltzer. The latest addition
Man, 30 who stunned doctors by surviving SIX aneurysms in one day returns to work six months later – at the hospital that saved him Billy Brogdon-Simmons collapsed suddenly while dressed as a toy soldier at a tree lighting ceremony at the hospital where he worked in November Scans revealed he had six high-risk brain
Researchers have discovered a new family of substances which has been found to display highly potent activity against the release of pro-inflammatory cytokines and the toxicity induced by reactive oxygen species (ROS). The novel compounds synthesized and evaluated belong to a family of low molecular weight substances named indolines. In early experiments, these compounds have
By creating multiple types of neurons from stem cells and observing how they interact, Salk scientists have developed a new way to study the connections between brain cells in the lab. Using the technique, which generates a partial model of the brain, the team showed how communication between neurons is altered in people with schizophrenia.
(HealthDay)—When it comes to both fun and efficiency, cross-country skiing is an exhilarating, high-calorie burner. It’s a lot less expensive than downhill skiing—all you need are the skis and a flat, snowy trail. But you can get the same benefits any time of year with a home Nordic or cross-country ski machine when you work
A letter from three University of Chicago researchers in this week’s New England Journal of Medicine updates a 47-year-old series of reports on the risks of exposure during pregnancy to a supplement, diethylstilbestrol (DES), that was once widely used but since 1971 has been linked to a rare cancer: clear-cell adenocarcinoma of the vagina and
(HealthDay)—Markers of reproductive history, including age of menarche and parity, may be tied to future diabetes risk in women with a body mass index (BMI) ≥25 kg/m², according to a study published in Diabetes, Obesity and Metabolism. Nirmala Pandeya, Ph.D., from the University of Queensland in Brisbane, Australia, and colleagues used data from 126,721 middle-aged
A new study on mice offers insights into why some people’s hair may turn gray in response to a serious illness or chronic stress. Publishing May 3 in the open access journal PLOS Biology, researchers at the National Institutes of Health and the University of Alabama, Birmingham have discovered a connection between the genes that
(HealthDay)—As America’s opioid crisis continues, too many toddlers are accidentally overdosing on narcotic medicines. But a new study suggests that better packaging might curb the problem. Among kids under the age of 6, single-dose packaging prompted a 79 percent decrease in the number of unintentional exposures to a narcotic called buprenorphine. The medication is given
After eight years of failed treatment for persistent atrial fibrillation (AF), Janet Szilagyi, 78 of Clayton, New Jersey, became the first patient in the United States to undergo cardiac ablation—a procedure in which an electrophysiologist will scar or destroy tissue in the heart that’s allowing incorrect electrical signals to cause an abnormal heart rhythm—using an
University of Illinois at Chicago researchers have discovered a way turn pluripotent stem cells into atrial cells, which make up the upper chambers, or atria, of the heart. The discovery will enable them to better study atrial fibrillation, the most common heart rhythm disorder also known as AFib, which originates in the heart’s atria. As
Move every day, cut down on oil and stick to one glass of wine: Proven things that DO lower your risk of breast cancer One in eight women will be diagnosed with breast cancer during her lifetime But there are steps you can take to reduce your risk of the deadly disease Exercising at least
A novel PET tracer developed by Korean researchers can visualize joint inflammation and could provide early diagnosis of rheumatoid arthritis, a common autoimmune disease that causes chronic inflammation of joints and can lead to deformity and dysfunction. The study is reported in the featured basic science article in The Journal of Nuclear Medicine‘s May issue.
A WSU research team is bringing together natural medical cures with modern biomedical devices in hopes of bringing about better health outcomes for people with bone diseases. In this first-ever effort, the team improved bone-growing capabilities on 3D-printed, ceramic bone scaffolds by 30-45 percent when coated with curcumin, a compound found in the spice, turmeric.
One major hallmark of cancer cells is their ability to adapt to stressful conditions such as nutrient deprivation. Rapidly growing tumor cells must compete for the ever-diminishing supply of nutrients in the surrounding environment to survive and proliferate. Targeting these adaptive mechanisms represents a promising approach for cancer therapeutics. Sanford Prebys Medical Discovery Institute (SBP)
As the brain grows and develops, nerve cells must make connections between one another in order to function properly. Brain cells are tightly packed together, so each cell might touch hundreds or thousands of other cells, and yet those cells only make stable and strong connections with a fraction of those neighboring cells. Researchers have
The message, “breast is best” may be familiar and powerful, but it’s not enough to get some women to breastfeed. A new University of Rochester Medical Center project creates a partnership with mothers who are not likely to breastfeed exclusively, and tries to improve the rates by first understanding their perspective and obstacles. Although Rochester
A new JBMR Plus review examines the negative impacts of weight loss surgery on bone health. The review of published studies notes that weight loss surgery can cause declines in bone mass and strength, and it is linked with an increased risk of bone fractures. Skeletal changes after surgery appear early and continue even after
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