A team of scientists from Loyola University Chicago's Stritch School of Medicine have discovered a critical component for renewing the heart's molecular motor, which breaks down in heart failure. Approximately 6.2 million Americans have heart failure, an often fatal condition characterized by the heart's inability to pump enough blood and oxygen throughout the body. This
As a dietitian, I get a lot of questions about blood sugar; especially about what’s normal, and how to lower it. First, it helps to know what blood sugar is and why it’s not good to have it be elevated. Blood sugar is a measure of glucose (“sugar”) in our blood. A bit about glucose:
Hospitalized COVID-19 patients with impaired first-phase ejection fraction were nearly 5 times more likely to die compared to patients with healthier measures of this early, often undetected sign of heart failure, according to new research published today in Hypertension, an American Heart Association journal. First-phase ejection fraction is a measure of the left ventricular ejection
People with prediabetes were significantly more likely to suffer a heart attack, stroke or other major cardiovascular event when compared with those who had normal blood sugar levels, according to research being presented at the American College of Cardiology's 70th Annual Scientific Session. Researchers said the findings should serve as a wake-up call for clinicians
Anemia rates among children and teenagers in India may be 20 per cent lower than currently reported as diagnosis is based on ethnically inappropriate blood count thresholds, a study argues. The study of hemoglobin concentrations in healthy Indian children aged zero to 19 found that the hemoglobin thresholds — or cut-offs — used to define
Researchers from the Boston University School of Public Health in the United States say there is no evidence to support a correlation between ABO blood group and the risk of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or the severity of coronavirus disease 2019 (COVID-19). The team’s systematic review of studies assessing the
Creating the best conditions for cells to make energy and survive critical illness is a challenge little understood in modern medicine. Now a new study led by scientists at the University of Plymouth, in collaboration with University College London and the Universities of Cambridge and Southampton, shows early signs that cells in some critically ill
A phase 2 clinical trial whose results were released today in STEM CELLS Translational Medicine might point to a way to overcome bronchopulmonary dysplasia (BPD), a major cause of death in preterm infants. The study, conducted by researchers at Samsung Medical Center, Sungkyunkwan University and Asan Medical Center Children's Hospital in Seoul, evaluates the effectiveness
Findings A UCLA research team has shown that using a truncated form of the CD4 molecule as part of a gene therapy to combat HIV yielded superior and longer-lasting results in mouse models than previous similar therapies using the CD4 molecule. This new approach to CAR T gene therapy — a type of immunotherapy that
Telehealth has become a critical way for doctors to still provide health care while minimizing in-person contact during COVID-19. But with phone or Zoom appointments, it's harder for doctors to get important vital signs from a patient, such as their pulse or respiration rate, in real time. A University of Washington-led team has developed a
Scientists at UC San Francisco, UC Berkeley and UCLA have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patient's own blood-forming stem cells. The trial will combine CRISPR technology developed at Innovative Genomics
Most people with cancer who are infected by the novel coronavirus produce antibodies at a rate comparable to the rest of the population–but their ability to do so depends on their type of cancer and the treatments they've received, according to a new study by researchers at Montefiore Health System and Albert Einstein College of
New research from the University of Minnesota Medical School suggests that disease-driving B cells, a white blood cell, play a role in the development of non-alcoholic fatty liver disease (NAFLD) – the most common chronic liver condition in the U.S. Their findings could lead to targeted therapies for NAFLD, which currently affects a quarter of
Six months after it was controversially hailed by Trump administration officials as a "breakthrough" therapy to fight the worst effects of Covid-19, convalescent plasma appears to be on the ropes. The treatment that infuses blood plasma from recovered Covid patients into people newly infected in hopes of boosting their immune response has not lived up
COVID-19 antibodies were found in the blood of about one in five donations from unvaccinated donors in the first week of March, American Red Cross data show. The organization tested more than 3.3 million donations from unvaccinated people in 44 states between mid-June 2020 and early March 2021. Across the entire period, about 7.5 percent
A groundbreaking new study led by University of Minnesota Twin Cities researchers from both the College of Science and Engineering and the Medical School shows for the first time that lab-created heart valves implanted in young lambs for a year were capable of growth within the recipient. The valves also showed reduced calcification and improved
New research at Washington University School of Medicine in St. Louis indicates that three new, fast-spreading variants of the virus that cause COVID-19 can evade antibodies that work against the original form of the virus that sparked the pandemic. With few exceptions, whether such antibodies were produced in response to vaccination or natural infection, or
A drug approved for diabetes has now been shown to also help patients with diabetes lose on average 10 percent of their body weight, UT Southwestern reports in a landmark international study. Semaglutide, an injectable medication taken once a week, offers a nonsurgical way to reduce weight and treat obesity. It could help the more
Researchers from Uppsala University show in a new study that inhibition of the protein EZH2 can reduce the growth of cancer cells in the blood cancer multiple myeloma. The reduction is caused by changes in the cancer cells' metabolism. These changes can be used as markers to discriminate whether a patient would respond to treatment
The coronavirus disease 2019 (COVID-19) pandemic continues to spread across the globe. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the disease exhibits an array of clinical outcomes (from asymptomatic to critical). The majority of cases are asymptomatic or minimally symptomatic, wherein there are no symptoms or only a few manageable ones.
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