Severity of illness, history of stroke, and being divorced or widowed were independently predictive of delirium in hospitalized patients in Zambia, according to a study published in PLOS ONE. A collaborative team of researchers from Vanderbilt University Medical Center and the University of Zambia Teaching Hospital published the risk factors as a follow-up look at
Chaperone protein imbalance can play a significant role in initiating toxic accumulation of tau in the aging brain—an early step in the development of Alzheimer’s disease and related neurodegenerative disorders known as tauopathies, a new preclinical study by University of South Florida Health (USF Health) neuroscientists suggests. In humans, misfolding of the protein tau leads
The fact that the human body is made up of cells is a basic, well-understood concept. Yet amazingly, scientists are still trying to determine the various types of cells that make up our organs and contribute to our health. A relatively recent technique called single-cell sequencing is enabling researchers to recognize and categorize cell types
The brain processes information using both slow and fast currents. Until now, researchers had to use electrodes placed inside the brain in order to measure the latter. For the first time, researchers from Charité – Universitätsmedizin Berlin and the Physikalisch-Technische Bundesanstalt (PTB), Berlin Institute, successfully visualized these fast brain signals from the outside – and
Glioblastomas are the most common and most aggressive brain tumors. Their survival rate has barely increased over the last 50 years, indicating an urgent need to develop new therapeutic strategies. In a paper published this week in the journal Molecular Cancer Therapeutics, a journal of the American Association for Cancer Research, the team led by
A team of New Jersey researchers has shown that changes in perceptual certainty and response bias, two central metrics of signal detection theory (SDT), correlate with changes in cognitive fatigue. They also show that SDT measures change as a function of changes in brain activation. This finding was reported in Frontiers in Psychology on January
Bipolar disorder affects millions of Americans, causing dramatic swings in mood and, in some people, additional effects such as memory problems. While bipolar disorder is linked to many genes, each one making small contributions to the disease, scientists don’t know just how those genes ultimately give rise to the disorder’s effects. However, in new research,
Bipolar disorder affects millions of Americans, causing dramatic swings in mood and, in some people, additional effects such as memory problems. While bipolar disorder is linked to many genes, each one making small contributions to the disease, scientists don’t know just how those genes ultimately give rise to the disorder’s effects. However, in new research,
Anabolic-androgenic steroids (AAS), a synthetic version of the male sex hormone testosterone, are sometimes used as a medical treatment for hormone imbalance. But the vast majority of AAS is used to enhance athletic performance or build muscle because when paired with strength training. AAS use increases muscle mass and strength, and its use is known
Dental cavities could significantly increase the risk of a life-threatening stroke from bleeding in the brain, according to new research. Past studies have shown a link between gum infection and stroke, but few studies have looked into what role dental cavities might play. In the new study, researchers looked specifically at cavities and intracerebral stroke,
Music-based interventions have become a core ingredient of effective neurorehabilitation in the past 20 years thanks to the growing body of knowledge. In this theme issue of Neurorehabilitation, experts in the field highlight some of the current critical gaps in clinical applications that have been less thoroughly investigated, such as post-stroke cognition, traumatic brain injury,
What: The Brain Prize has been awarded to Michael A. Moskowitz, M.D., a professor of neurology at Harvard Medical School at the Massachusetts General Hospital, Charlestown, who also is supported by an NIH grant. The Brain Prize is "the world's most prestigious award for brain research" and is awarded by the Lundbeck Foundation, Denmark. Dr.
Using genetic engineering, researchers at UT Southwestern and Indiana University have reprogrammed scar-forming cells in mouse spinal cords to create new nerve cells, spurring recovery after spinal cord injury. The findings, published online today in Cell Stem Cell, could offer hope for the hundreds of thousands of people worldwide who suffer a spinal cord injury
Research from the University of Kent has led to the development of the MeshCODE theory, a revolutionary new theory for understanding brain and memory function. This discovery may be the beginning of a new understanding of brain function and in treating brain diseases such as Alzheimer’s. In a paper published by Frontiers in Molecular Neuroscience,
The coronavirus disease 2019 (COVID-19) pandemic has claimed well over 2.4 million lives, but its long-term sequelae are still being identified. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produces an infection that may be associated with a wide spectrum of disease, from asymptomatic to critical or terminal respiratory failure or multi-organ dysfunction. A new
How come we don't hear everything twice: After all, our ears sit on opposite sides of our head and most sounds do not reach both our ears at exactly the same time. While this helps us determine which direction sounds are coming from, it also means that our brain has to combine the information from
Amyloid plaques are aggregates of misfolded proteins that form in the spaces between nerve cells. These abnormally configured proteins are thought to play a central role in Alzheimer's disease. The amyloid plaques first develop in the areas of the brain concerned with memory and other cognitive functions. The amyloid hypothesis Amyloid plaques form when pieces
Amnesia or memory loss is associated with stress, anxiety and frustration and is often very distressing for the patient as well as for his or her family and friends. Types of treatment for amnesia Treatment of amnesia and memory loss include (1-4): Cognitive therapy using speech or language therapist can be of help in patients
Amnesia or memory loss is associated with stress, anxiety and frustration and is often very distressing for the patient as well as for his or her family and friends. Types of treatment for amnesia Treatment of amnesia and memory loss include (1-4): Cognitive therapy using speech or language therapist can be of help in patients
The definition of vision impairment by the Centers for Disease Control and Prevention (CDC) says a visually impaired person’s eyesight cannot be corrected to a “normal level”. It may be said that visual impairment is the functional limitation of the eye or eyes or the vision system. This leads to (1-5) – Loss of visual
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