People are continuously exposed to a huge amount and variety of potentially toxic chemicals present in the surrounding environment, such as pesticides or drugs traces in water, soil, air and living organisms. The combined action of pollutants can increase the risk of toxic effects. At the same time, a growing occurrence of cardiovascular diseases has
Ischemic stroke, the second leading cause of death worldwide, occurs when a vessel to the brain is blocked, reducing blood flow to the brain and depriving it of critical supplies of oxygen and nutrients. This process leads to the death of brain cells and leaves the patient with a sudden loss of certain body functions.
Cancer cells sometimes develop resistance to the cytotoxic drugs used in chemotherapy. Figuring out why the treatment isn’t working and why it may even defeat its own purpose is therefore important to understand. “We haven’t understood very much about how this resistance to chemotherapy develops and even less about how the microenvironment in cancer can
The Senate’s release of its bipartisan infrastructure plan signals that lawmakers are poised to throw former President Donald Trump’s belated bid to lower Medicare drug prices under the bus — not to mention trains, bridges, tunnels and broadband connections. That’s because the massive spending bill is the first of two likely to at least delay
WEHI has partnered with Boehringer Ingelheim, a leading research-driven pharmaceutical company, in a collaboration to discover and develop anti-cancer therapeutics using a promising new technology called targeted protein degradation. The partnership builds on more than 25 years of pioneering discoveries at WEHI, into a family of proteins known as the inhibitor of apoptosis proteins (IAPs)
The hormone prolactin has long been understood to play a vital role in breast growth and development and the production of milk during pregnancy. But a pair of recent studies conducted at VCU Massey Cancer Center finds strong evidence that prolactin also acts as a major contributor to breast cancer development and that the hormone
Fox News Flash top headlines for March 29 Fox News Flash top headlines are here. Check out what’s clicking on Foxnews.com. A study led by the National Institute on Drug Abuse (NIDA) claims that adolescents (ages 12-17) are more likely to develop a substance abuse disorder after trying marijuana or misusing prescription drugs. “Research has
Millions of children weighing less than 15kg are currently denied access to Ivermectin treatment due to insufficient safety data being available to support a change to the current label indication. The WorldWide Antimalarial Resistance Network (WWARN)'s new meta-analysis published today provides evidence that supports removing this barrier and improving treatment equity. A systematic review and
Danjuma Adda, a Nigerian public health expert, became the president-elect of the World Hepatitis Alliance (WHA) in November last year. He is the first African to hold the position. Having been infected and lost his mother to hepatitis B, Adda's personal experience has fueled his passion and drive for a paradigm shift in fighting the
New research at Washington University School of Medicine in St. Louis indicates that three new, fast-spreading variants of the virus that cause COVID-19 can evade antibodies that work against the original form of the virus that sparked the pandemic. With few exceptions, whether such antibodies were produced in response to vaccination or natural infection, or
The coronavirus disease 2019 (COVID-19) pandemic – caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – is still causing hundreds of thousands of new cases globally. Therapeutic antibodies have been used to attempt to counter and contain the virus. Convalescent plasma (CP) obtained from recovered COVID-19 patients is also in use in many
A counterfeit medication or drug is defined as a pharmaceutical product that is produced and sold with the intention to deceive the consumer about the origin, authenticity or efficacy of the product. This has the potential to be dangerous for consumers as the formulation may contain unusual ingredients or quantities of the ingredients, which can
Insomnia is a very common sleep disorder, and presents in various types. However, sleep maintenance insomnia (SMI) is the most frequent complaint. Both the cause of awakening and the difficulty in returning to sleep are important in precipitating episodes of nocturnal sleep disturbances. Research seems to suggest that hyperarousal states, personality traits, and physiologically determined
Cells in the nasal passages and upper airways are likely the coronavirus’ major point of entry into the body, according to a study by Stanford Medicine researchers. The finding further supports the use of masks to prevent viral spread and suggests that nasal sprays or rinses might be effective in blocking infection by the coronavirus.
Are the potentially crippling side-effects of new cancer ‘wonder drugs’ worth the risk? Patients with otherwise untreatable tumours benefiting from immunotherapy The treatment costs around £100,000 per patient per year, and has side-effects One in ten patients given immunotherapy for cancer suffer rheumatoid arthritis Surviving cancer against the odds can give patients a new lease
More than 20 million people in the U.S. suffer neuropathic pain. At least 25% of those cases are classified as unexplained and considered cryptogenic sensory polyneuropathy (CSPN). There is no information to guide a physician’s drug choices to treat CSPN, but a researcher from the University of Missouri School of Medicine and MU Health Care
The NHS would spend billions of pounds more on drugs if it had to pay US prices following a US/UK trade deal. According to a new study by researchers at Brigham and Women’s Hospital in Boston, Harvard Medical School, and the University of Oxford, published by the Journal of the Royal Society of Medicine, NHS
Scientists have described a potential new therapeutic strategy for slowing down early-stage Huntington’s disease in a new study published today in eLife. The research in mice indicates that targeting the histamine H3 receptor (H3R) – a well-established drug target for other conditions such as hay fever—could help to prevent imbalances in dopamine signaling that lead
Life in lockdown may not last forever but Bill Gates is probably right in saying we will not return to normal until a vaccine has been rolled out worldwide. This could be many months, if not years away. In the meantime, we provide supportive treatment to the most severely affected patients and look into our
Specific combinations of statins and antihypertensives may also reduce risk for Alzheimer’s disease, according to a new USC study of nearly 700,000 Medicare beneficiaries. The findings suggest that treatments already in use for blood pressure and cholesterol control could reduce the number of people with Alzheimer’s and related dementias, researchers said. The study was published
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