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A COVID-19 vaccine candidate that underwent extensive preclinical testing at the University of Alabama at Birmingham this spring and summer shows potent preclinical immune responses—including several that distinguish it from other COVID-19 vaccine approaches—according to a preprint deposited in the BioRxiv repository this week. Partial preclinical results had been announced in July and August by

Millions of people in northern England are anxiously waiting to hear how much further virus restrictions will be tightened as one of the British government’s leading medical advisers warned Sunday that the country is at a crucial juncture in the second wave of the coronavirus. England’s deputy chief medical officer, Professor Jonathan Van-Tam, said the

THURSDAY, Oct. 8, 2020 — Kids who reach puberty earlier than other kids are at an increased risk of harming themselves as teens, British researchers report. “Our study is the first to investigate the relationship between the timing of puberty and self-harm using an objective measure of pubertal timing in boys,” said lead author Elystan

Scientists at St. Jude Children’s Research Hospital have visualized previously unknown structures of the ABL kinase, offering insight for designing the next generation of targeted therapies for adult and childhood cancers. The work will advance understanding of treatment resistance to targeted cancer therapies. The findings appear as an advance online publication today in Science. Central

THURSDAY, Oct. 1, 2020 — Home-based motor training telerehabilitation is beneficial for stroke patients, with enhanced interhemispheric functional connectivity of the M1 areas, according to a study published online Sept. 30 in Neurology. Jing Chen, Ph.D., from Fudan University in Shanghai, and colleagues randomly assigned 52 stroke patients with hemiplegia to home-based motor training telerehabilitation

The pandemic, which has disrupted so much of our lives, has shaken up health benefits, too—and sometimes for the better. Over 150 million Americans, including nearly half the population of Texas, get health coverage through an employer. And next month, many workers will select their health benefits during open enrollment. They’re likely to see a

MONDAY, Sept. 21, 2020 — Nearly half of all school employees meet the U.S. Centers for Disease Control and Prevention definition for increased or potentially increased risk for severe COVID-19, according to a study published online Sept. 17 in Health Affairs. Thomas M. Seldon, Ph.D., from the Agency for Healthcare Research and Quality in Rockville,

Up to one in four Danes has an unhealthy accumulation of fat in the liver, also known as fatty liver. Fatty liver is rarely the cause of symptoms in itself, but people with fatty liver have an increased risk of developing diabetes. Exactly how the two diseases are linked has, however, so far been unknown.

A Rutgers-led team has created a smart drug delivery system that reduces inflammation in damaged nervous tissues and may help treat spinal cord injuries and other neurological disorders. The system, which uses extremely thin biomaterials implanted in the body, also protects nerve fibers (axons) that connect nerve cells in injured neural tissues, according to a

Is there any candy worthier of shoveling into your mouth at a rapid pace than Reese’s Pieces? Seriously! Whether it’s pouring a handful into my bowl of popcorn, topping ice cream sundaes, or simply eating them out of the palm of my own hand, I will never get sick of these little bits of happiness.

It’s known as “New York’s Best Kept Secret.” It’s Ross and Marshalls, before Ross and Marshalls became a thing. Century 21 — the iconic New York department store founded by cousins by Sonny and Al Gindi in 1961 — and which became known for their killer selection of designer goods offered at bargain prices is

(HealthDay)—Disease-modifying antirheumatic drug (DMARD) therapy for rheumatoid arthritis (RA) treatment also cuts cardiovascular disease (CVD) risk, according to a study published online Aug. 28 in the Annals of the Rheumatic Diseases. Sven Plein, M.D., Ph.D., from the University of Leeds in the United Kingdom, and colleagues randomly assigned 81 patients with early RA to either

People enrolled in a pharmacist-led telemonitoring program to control high blood pressure were about half as likely to have a heart attack or stroke compared to those who received routine primary care, according to new research published today in Hypertension, an American Heart Association journal. Researchers, led by study author Karen L. Margolis, M.D., M.P.H.,

When Lauren Langbein became a doctoral student in cell biology at Thomas Jefferson University in Philadelphia in 2014, she was used to being a stellar student—she had always excelled in classrooms and labs. But by the end of 2016, her research project was falling apart, and Langbein, a native of Monmouth County, N.J., and a

An international group of hearing specialists has released a new set of recommendations emphasizing that cochlear implants should be offered to adults who have moderate to severe or worse hearing loss much more often than is the current practice. The group hopes the recommendations help increase usage of such devices, potentially improving hearing and quality

(HealthDay)—In a 2020 American Diabetes Association clinical guideline, published online Sept. 1 in the Annals of Internal Medicine, recommendations are presented for the pharmacologic treatment of adults with type 2 diabetes. Kacie Doyle-Delgado, D.N.P., from St. Mark’s Hospital and St. Mark’s Diabetes Center in Salt Lake City, and colleagues updated recommendations relating to the pharmacologic

A team of researchers has been modeling the potential spread of the coronavirus pandemic in Italy. Using their model, they can calculate the number of exposed and highly infectious individuals and the daily isolation efforts required to bring down the epidemic curve. In April, a team led by Professor Andrea Rinaldo, the head of EPFL’s

A 25-year-old man now relies on a wheelchair after his symptoms of a severe health condition were misdiagnosed as anxiety for years. Zachary Moyer, from Kansas City, Missouri, started struggling with his health when he was just six years old. He would get sore throats, severe earaches, bad coughs and fevers, with no known cause.

(HealthDay)—Disparities in COVID-19 cases are seen in one or more underrepresented racial/ethnic groups in almost all hot spots in the United States, according to research published in the Aug. 14 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report. Jazmyn T. Moore, M.P.H., from the CDC COVID-19 Response

Many people who suffer a stroke are permanently disabled. Stroke remains the leading cause of long-term disability in the United States. Paralysis of one side of the body, speech and language problems, vision problems and memory loss are some of the major consequences of stroke injury. Every year, nearly 800,000 people in the United States