Tag: identified

A new study led by researchers at Washington State University has identified a protein that could be the key to improving treatment outcomes after a heart attack. Published in the Journal of Biological Chemistry, the research suggests that protein kinase A (PKA) plays a role in heart muscle cell necrosis, a major type of cell

Researchers in the Department of Neurology at Tohoku University, which is led by professor Masashi Aoki, have developed a classification scheme for neuromyelitis optica spectrum disorder, a rare autoimmune disease that until recently was thought to be a type of multiple sclerosis (MS). The new taxonomy for the disease replaces one borrowed from MS but

An abdominal aortic aneurysm (AAA) is a bulging of the aorta, the body’s main blood vessel, which runs from the heart down through the chest and stomach. Prevalence of AAA in the population is high, up to nearly 13% depending on age group, particularly for men aged 65 and over. An AAA can get bigger

Primary sclerosing cholangitis (PSC) is a rare chronic inflammatory disease of the bile ducts and is difficult to treat, since its causes have not yet been adequately researched. Using RNA sequencing, an international research consortium led by Michael Trauner, Head of MedUni Vienna’s Division of Gastroenterology and Hepatology (Department of Medicine III), has now identified

Highly contagious coronavirus variant becomes dominant in US Fox News medical contributor Dr. Janette Nesheiwat joins ‘America’s News HQ’ Massachusetts health officials on Sunday announced the state’s first known case of the more contagious coronavirus variant initially detected in the U.K, known as B.1.1.7. The mutated strain was detected in a female Boston resident in her 20s who

Osteoarthritis is one of the most common problems associated with aging, and although there are therapies to treat the pain that results from the breakdown of the cartilage that cushions joints, there are no available therapies to modify the course of the disease. However, working in a mouse model of the disorder, researchers at Washington

A research team led by Professor Takumi Toru of Kobe University’s Graduate School of Medicine (also a Senior Visiting Scientist at RIKEN Center for Biosystems Dynamics Research) have identified ‘social cells’ in the brain that are related to social behavior. The cells were identified via Ca imaging conducted using a microendoscope. It is expected that

How cells recognize pathogens and alert the immune system swiftly is a fundamental process of high importance for the survival of any species, including humans. A key role is ascribed to so-called adapters—little molecular platforms inside cells where signals from pathogen detectors are integrated for safety and accuracy and conveyed to lasting signals leading to

Obstructive Sleep Apnea (OSA) affects an estimated 22 million Americans. In addition to sleep problems, the condition can cause other health issues, including high blood pressure, chronic heart failure and stroke. Some patients with OSA are at an even higher risk of cardiovascular problems because of a phenomenon called “reverse dipping” that causes blood pressure

An artificial intelligence (AI) tool—trained on roughly a million screening mammography images—identified breast cancer with approximately 90 percent accuracy when combined with analysis by radiologists, a new study finds. Led by researchers from NYU School of Medicine and the NYU Center for Data Science, the study examined the ability of a type of AI, a

Researchers from the National Institute for Physiological Sciences in Japan have identified the neurons responsible for relaying sweet taste signals to the gustatory thalamus and cortex in mice. While the peripheral taste system has been extensively investigated, relatively little is known about the contribution of CNS gustatory neurons in the sensation of taste. In this

For most of human history Parkinson’s disease (PD) has been a rare disorder. However, demography and the by-products of industrialization a now contributing to an impending a Parkinson’s pandemic, according to experts writing in a supplement to the Journal of Parkinson’s Disease. They say that this pandemic can be addressed by the Parkinson’s community forming

Older mice who are surgically joined with young mice in order to share a common bloodstream get stronger and healthier, making parabiosis one of the hottest topics in age research. Publishing in Nature Metabolism, researchers from the Buck Institute report that MANF (mesencephalic astrocyte-derived neurotrophic factor) is one of the factors responsible for rejuvenating the

St. Jude Children’s Research Hospital scientists have discovered a subset of helper T cells that may help to redefine understanding and treatment of chronic, debilitating inflammatory disorders. The research appears today as an advance online publication in the journal Nature. The study focused on a family of helper T cells called Th17 cells. Th17 cells

In an article published online by Frontiers in Endocrinology, researchers at the Medical University of South Carolina (MUSC) report that they have identified a potential therapeutic target for lung fibrosis or scarring. They showed in a preclinical model that the protein promotes fibrosis by turning on profibrotic genes and increasing levels of profibrotic factors, including

In experiments performed in mice, Johns Hopkins researchers report they have identified the cascade of cell death events leading to the physical and intellectual degeneration associated with Parkinson’s disease. Results of the study, published Nov. 2 in Science, suggest promising new targets for drugs that could interrupt Parkinson’s disease progression. The study, the researchers say,

In a new study researchers have developed a two-pronged approach for targeting Ebola virus infection using linked nucleic acid (LNA) antisense oligonucleotides (ASOs)designed to interfere both genes essential for translation of Ebola virus genes and to block production of an intracellular human protein needed for the virus to enter cells. The results of using LNA

A new study by KAIST researchers identified where the mutation causing glioblastoma starts. According to the study, neural stem cells away from the tumor mass are the cells of origin that contain mutation drivers for glioblastoma, one of the most aggressive brain tumor. This breakthrough research, reported in Nature on August 1, gives insights for

A large team of researchers from the U.S. and China has succeeded in identifying a number of RNA fragments found in human fat tissue. In their paper published in the journal Science Translational Medicine the group describes their study of the fragments they found and their possible links with obesity. Prior research has reported RNA

According to a report by the World Health Organization, close to 1 in 10 people in the world are affected by anxiety and/or depression. Alarmingly, the amount has nearly doubled, from 416 million to 615 million, between 1990 and 2013. Since adequate treatments are still lacking for many patients, the scientists at the Max Planck