A study led by researchers at the University of Chicago and Indiana University has determined that a protein called elF5A is necessary for driving inflammation in macrophage cells in obesity. Blocking DHPS, the enzyme that modifies and activates elF5A, led to reduced inflammation and improved glucose control in mice. The study was published on September
Stroke, a devastating condition that causes damage to the brain due to interruption of blood supply, is often considered an adult disease. But children can experience strokes as well. Sadly, pediatric stroke affects one in every 4,000 newborns and an additional 2,000 older children each year. The most common cause of stroke in children is
Researchers have discovered a specific brain region underlying ‘goal-directed behavior’ – that is, when we consciously do something with a particular goal in mind, for example going to the shops to buy food. The study, published today in the journal Neuron, found that marmoset monkeys could no longer make an association between their behavior and
A new study published in the Journal of the National Cancer Institute is the first to examine the opinions and experiences of clinical oncologists working at a major medical center on the Federal Right to Try (RTT) law. Enacted in 2018, the Federal RTT law was created as a new and parallel pathway to the
New Cornell-led research shows that inadequate funding is the main barrier to better surveillance and control of ticks, including the blacklegged tick, which spreads Lyme disease, the No. 1 vector-borne illness in the country. Insufficient infrastructure, limited guidance on best practices and lack of institutional capacity also are impediments to improved tick monitoring, the researchers
A new review, published in BMC Public Health, identifies the macroeconomic determinants of health and health inequalities. The social determinants of health have been widely recognized yet there was, until now, a lack of clarity about the specific ways in which large economic factors influence health and what can be done to address these issues.
Researchers from the UCLA School of Dentistry have provided insight into how the mechanical process of bone loss works and have also identified a protein that is responsible for recycling of the cells that can also promote bone loss. The team showed that by eliminating a key protein responsible for the activation of bone loss,
(HealthDay)—Computer-aided colonoscopy can reliably diagnose small polyps that do not need to be removed, according to a study published online Aug. 14 in the Annals of Internal Medicine. Yuichi Mori, M.D., Ph.D., from the Showa University Northern Yokohama Hospital in Japan, and colleagues evaluated the performance of real-time computer-aided diagnosis (CAD) with endocytoscopes (×520 ultra-magnifying
A study led by researchers at Center for Infection and Immunity (CII) at Columbia University’s Mailman School of Public Health and the Department of Medicine at the Columbia University Irving Medical Center reports on the use of a genetic sequencing method to identify viral pathogens behind unexplained respiratory illnesses in Uganda over a five-year period.
Do you know someone afflicted with Alzheimer’s disease? Odds are the answer to that question is yes, since Alzheimer’s is one of the most common age-related disorders in the United States. It’s also the fifth-leading cause of death among adults aged 65 and older. But as pervasive as the disease may be, one of its
Prostate cancer breakthrough: New DNA test identifies men who are SIX TIMES more likely to develop the disease Researchers identified 63 new genetic mutations linked to the condition Combined with over 100 variants known to cause the cancer to make the test One in 100 men carry sufficient numbers of genetic variations to put them
Researchers at Emory University have found that depressed patients who have not responded to multiple antidepressants exhibit evidence of increased inflammation. Findings were recently published online in the journal, Psychoneuroendocrinology. The study shows that antidepressant treatment resistance is associated with increased inflammatory markers in patients with depression. One third of patients with depression fail to
In a recent study published in the Journal of Clinical Investigation, Mayo Clinic researchers identified that an FDA drug approved for myelodysplastic syndrome may be useful to treat triple-negative breast cancer, which is one of the most aggressive and lethal types of breast cancer. In this study, Mayo investigators identified that the drug 5-aza-2′-deoxycytidine (decitabine)
A new study led by a UTSA researcher examines the social perceptions of Pre-Exposure Prophylaxis (PrEP), a medication to prevent HIV, among gay and bisexual men in Texas. The U.S. Food and Drug Administration (FDA) approved the use of PrEP in 2012. While evidence suggests that the medication is effective in preventing the spread of
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