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COVID-19 antibodies found in one in five U.S. blood donations

COVID-19 antibodies were found in the blood of about one in five donations from unvaccinated donors in the first week of March, American Red Cross data show. The organization tested more than 3.3 million donations from unvaccinated people in 44 states between mid-June 2020 and early March 2021. Across the entire period, about 7.5 percent

Rates of macrolide resistance in S. pneumoniae high across the U.S.

(HealthDay)—There are high rates of macrolide-resistant Streptococcus pneumoniae throughout the United States, according to a study published online Feb. 4 in Open Forum Infectious Diseases. Vikas Gupta, Pharm.D., from Becton, Dickinson and Company (BD) in Franklin Lakes, New Jersey, and colleagues used the BD Insights Research Database to identify 3,626 patients with a positive S.

Prescribing of psychotropic meds up in nursing homes during COVID-19

(HealthDay)—Prescribing of psychotropic drugs increased for residents of nursing homes in Ontario, Canada, from January-February 2020 to March-September 2020, according to a study published online March 16 in JAMA Internal Medicine. Nathan M. Stall, M.D., from Sinai Health and the University Health Network in Toronto, and colleagues examined the monthly proportion of nursing home residents

Prescribing of psychotropic meds up in nursing homes during COVID-19

(HealthDay)—Prescribing of psychotropic drugs increased for residents of nursing homes in Ontario, Canada, from January-February 2020 to March-September 2020, according to a study published online March 16 in JAMA Internal Medicine. Nathan M. Stall, M.D., from Sinai Health and the University Health Network in Toronto, and colleagues examined the monthly proportion of nursing home residents

Research shows how mutations in SARS-CoV-2 allow the virus to dodge immune defenses

The vast majority of people infected with SARS-CoV-2 clear the virus, but those with compromised immunity—such as individuals receiving immune-suppressive drugs for autoimmune diseases—can become chronically infected. As a result, their weakened immune defenses continue to attack the virus without being able to eradicate it fully. This physiological tug-of-war between human host and pathogen offers

Pre-term births in Tennessee decreased during pandemic

Statewide stay-at-home orders put in place as Tennessee fought to control the spread of coronavirus last March were associated with a 14% lower rate of preterm birth, according to a research letter published today in JAMA Pediatrics. Preterm infants have higher morbidity and mortality risks than babies born at term. Senior author Stephen Patrick, MD,

RNA editing protein ADAR1 protects telomeres and supports proliferation in cancer cells

Scientists at The Wistar Institute identified a new function of ADAR1, a protein responsible for RNA editing, discovering that the ADAR1p110 isoform regulates genome stability at chromosome ends and is required for continued proliferation of cancer cells. These findings, reported in Nature Communications, reveal an additional oncogenic function of ADAR1 and reaffirm its potential as

CVD risk factors tied to cognitive impairment in schizophrenia

(HealthDay)—Cardiovascular risk factors are associated with cognitive impairment among individuals with schizophrenia, according to a review and meta-analysis published online March 3 in JAMA Psychiatry. Katsuhiko Hagi, Ph.D., from Sumitomo Dainippon Pharma in Tokyo, and colleagues conducted a systematic review and meta-analysis to examine the association between risk factors for cardiovascular disease (CVD) and cognition

Covid cases rising again in Europe: WHO

The number of new coronavirus cases has risen in Europe after six weeks of decline, the World Health Organization said on Thursday. “Last week, new cases of COVID-19 in Europe rose nine percent to just above one million. This brought a promising six-week decline in new cases to an end, with more than half of

Nanoparticle-delivered COVID-19 vaccine candidate shows promise in preclinical studies

Researchers from Cleveland Clinic’s Global Center for Pathogen Research & Human Health have developed a promising new COVID-19 vaccine candidate that utilizes nanotechnology and has shown strong efficacy in preclinical disease models. According to new findings published in mBio, the vaccine produced potent neutralizing antibodies among preclinical models and also prevented infection and disease symptoms

A new theory for how memories are stored in the brain

Research from the University of Kent has led to the development of the MeshCODE theory, a revolutionary new theory for understanding brain and memory function. This discovery may be the beginning of a new understanding of brain function and in treating brain diseases such as Alzheimer’s. In a paper published by Frontiers in Molecular Neuroscience,

Moderate-to-vigorous physical activity and less sitting reduce the risk of diabetes in older adults

According to a recent study, moderate-to-vigorous physical activity and less sedentary time improve glucose metabolism and reduce the risk of type 2 diabetes in older adults. Based on the results, it is important to encourage older adults to avoid sedentary time and increase moderate-to-vigorous physical activity to improve their glucose metabolism. The study is part

New coronavirus variant in NYC has vaccine-evading mutation

A new coronavirus variant with concerning mutations is on the rise in New York City, according to news reports. This latest coronavirus variant, dubbed B.1.526, first emerged in New York in November 2020, and it now accounts for about 25% of coronavirus genomes that were sequenced from New York in February and posted to a

Study pinpoints role of language disruptions in psychosis

Just as a small airport would have challenges handling massive plane traffic, people with psychosis may experience communication difficulties because non-language parts of the brain are trying to manage communications tasks, new research from Western and Lawson Health Research Institute shows. Difficulties with communication—the ability to use language and to comprehend what others are saying—are