Tag: lead

A new anti-viral drug could improve COVID-19 outcomes and survival rates—and is highly effective against multiple variants—according to a new study led by researchers at the University of British Columbia and Université de Sherbrooke. The drug, called N-0385, blocks the SARS-CoV-2 virus from entering human cells through its favored cell gateways. The results of the

Adagio Therapeutics today published in vitro and in vivo data in Science on its lead antibody candidate, ADG2, which demonstrated similar or higher potency against SARS-CoV-2 compared to other monoclonal antibodies (mAbs) in clinical development and strong binding to all known SARS-CoV-2 variants. Uniquely, ADG2 also showed broad and potent neutralization against a range of

New UK research has found that being male or obese reduces chance of survival from severe coronavirus disease (COVID-19). The findings come from a study of almost 17,000 patients with COVID-19, in which researchers from three universities, including Imperial, aim to answer important questions about the course of and risk factors for the disease. According

Intimate partner abuse can have long-lasting effects. Even when the abuse happens early in one’s life, the damage may carry through until old age and can lead to heightened risk of depression and thoughts of suicide. A team of researchers from UT studied the best ways to help older adults who have experienced this type

Vaping is widely assumed to be safer than cigarette smoking, but scientists at the University of North Carolina School of Medicine have uncovered evidence suggesting that vaping promotes the same cellular responses found in smokers who suffer with emphysema. In a study published in the American Journal of Respiratory and Critical Care Medicine, the UNC

The human liver is a vital organ involved in multiple functions. Because susceptibility to liver diseases is highly variable among patients, researchers from Tokyo Medical and Dental University (TMDU) and Cincinnati Children’s Hospital Medical Center (CCHMC) have engineered a model liver system that can be personalized for disease modeling and drug discovery. In a study

In a landmark study, scientists at Houston Methodist Research Institute discovered what makes white blood cell counts spike in individuals who have high cholesterol, possibly leading to new therapies for heart disease. Led by Longhou Fang, Ph.D., an associate professor in the Center for Cardiovascular Regeneration, and his postdoctoral fellow Qilin Gu, Ph.D., the team

If you’re going to choose dessert first, then the high-calorie option might lead to your eating a healthier meal, unless you have a lot on your mind, according to new research published by the American Psychological Association. Researchers placed either a healthy or less healthy dessert (fresh fruit vs. lemon cheesecake) at the beginning or

How does lead on the Psyche of the people? More and more people in the world suffer from problems with their mental health. Doctors have now found out that people who were exposed as children to a particular toxic metal, are more likely to have mental health problems and behavioural disorders. Unfortunately, this metal was

England rugby stars lead heart-warming campaign to raise £500,000 for a drug that could save a 10-year-old boy’s life by stopping his cancer coming back for the THIRD time Harry Banks, from Bedfordshire, has already had neuroblastoma twice In November the cancer returned in his brain after two years in remission It was removed with

Bowel (colorectal) cancer is the third most commonly occurring cancer in men and the second most commonly occurring cancer in women worldwide. The global burden is expected to increase by 60 per cent to more than 2.2 million new cases and 1.1 million deaths by 2030. The research, which has been published in the Journal

Research has shown that getting a good night’s sleep plays an important role in children’s growth and development, both physically and emotionally. When children face an unsettling experience, such as the injury of a parent, it can alter their sleep habits, according to new research being presented at the 2018 American Academy of Pediatrics National

Two presurgery checklists from the American College of Surgeons (ACS) Strong for Surgery (S4S) program that incorporate best practices for engaging patients in preparing for their upcoming operations significantly improved lifestyle factors that pose an increased risk for postoperative complications or help support healing and postoperative recovery. At CHRISTUS St. Michael Health System, Texarkana, Tex.,

New research from the University of Georgia reveals that exposure to famine during specific moments in early life is associated with depression later in life. “Nutrition deprivation and stress are important risk factors for depression particularly during periods in early life,” said lead author Changwei Li, assistant professor of epidemiology and biostatistics at UGA’s College

Women with thyroid dysfunction in the first half of pregnancy face an increased risk for gestational diabetes, a form of diabetes that is typically diagnosed during the second trimester, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. Thyroid dysfunction is common among pregnant women and has been

A drug that reduces delirium in postoperative patients may work by preventing the overactivity of certain receptors in brain cells, according to a new study published in the Online First edition of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists (ASA). The researchers say the findings could lead to more widespread use

Insomnia causes the brain to ‘eat itself’ and may lead to Alzheimer’s, study finds Sleep is important to clear away brain cell ‘wear and tear’, research suggests Yet, insomnia causes this to go into overdrive and remove healthy brain cells Previous research suggests the removal of such cells is linked to Alzheimer’s The study was

Growing levels of resistance to antifungal treatments could lead to increased disease outbreaks and affect food security around the world. An international team, led by researchers from Imperial College London and the University of Exeter, warns that improvements are needed in how existing drugs are used, as well as an increased focus on the discovery

It’s a familiar scenario: You find yourself at the doctor’s office, sitting on the edge of an exam table with your feet dangling inches above the floor. The nurse or medical assistant who seconds ago instructed you to sit now asks you questions about the reason for your visit—all while taking your blood pressure. That

It’s a discovery more than seven years in the making that researchers believe will vastly illuminate our understanding of deadly brain tumors. Gliomas are the most common type of central nervous system cancer but how these tumors develop is not fully understood. Sheri Holmen, PhD a researcher at Huntsman Cancer Institute (HCI) and professor of