A computer model developed by Cleveland Clinic oncologist Timothy Chan, MD, Ph.D., and colleagues accurately predicts whether immune checkpoint blockade (ICB) will be effective in patients diagnosed with a wide variety of cancers. The forecasting tool, developed using machine learning, assesses multiple biological and clinical variables in an individual patient’s condition to predict the degree
Active or voluntary learning is a major topic in education, psychology, and neuroscience. Over the years, numerous studies have shown that when learning occurs through voluntary action, there is a modulation of attention, motivation and cognitive control that makes the process much more effective. Consequently, memory is benefited. However, although the physiological processes underlying this
Dealing with a global pandemic has taken a toll on the mental health of millions of people. A team of MIT and Harvard University researchers has shown that they can measure those effects by analyzing the language that people use to express their anxiety online. Using machine learning to analyze the text of more than
Research scientists from Regenstrief Institute and Indiana University have further improved the performance of Uppstroms, a machine learning application that identifies patients who may need referrals to wraparound services, by incorporating additional personal and population-level data sources and advanced analytical approaches. Research team affiliations include Regenstrief, IU Fairbanks School of Public Health at IUPUI, IU
A sophisticated type of artificial intelligence (AI) called deep learning can help rapidly detect blockages in the arteries that supply blood to the head, potentially speeding the onset of life-saving treatment, according to a study published in Radiology. Large vessel occlusions are blockages in the arteries that supply oxygenated blood to the brain. These occlusions
Prolonged sleep deprivation can lead to severe health problems in humans and other animals. But why is sleep so vital to our health? A UCLA-led team of scientists has answered this question and shown for the first time that a dramatic change in the purpose of sleep occurs at the age of about 2-and-a-half. Before
When Simon Thomas’s wife, Caroline, got sick, he got serious. “It was the hardest thing we had encountered as a family,” says the 40-year-old police sergeant from Llanelli, Wales, UK. After years of making great family memories—but also putting on weight—Thomas knew he wanted to be at his healthiest to take care of his wife
Researchers working in The N.1 Institute for Health at NUS, led by Assistant Professor Camilo Libedinsky from NUS Psychology, and Senior Lecturer Shih-Cheng Yen from the Innovation and Design Programme at NUS Engineering, have discovered that a population of neurons in the brain’s frontal lobe contain stable short-term memory information within dynamically-changing neural activity. This
Shawn Johnson may be in the third trimester of her pregnancy, but she’s still keeping the romance alive with her husband, Andrew East. “We try to [but] it’s very different,” the Olympian gymnast, 27, told Us Weekly exclusively on Wednesday, July 31, while promoting her Philips Avent Bottle partnership. “My husband is, bless him, just
Too little sunlight—and specifically UVB exposure—in pregnancy has been linked with a higher risk of learning disabilities. In a new study looking at more than 422,500 school-age children from across Scotland, researchers found that low UVB exposure during pregnancy was associated with risk of learning disabilities. UVB exposure from sunlight is linked to the production
Gold coins in ancient India reached their peak with the Gupta emperors from the 3rd to 6th century AD. This was India's Golden Age, where there was prosperity all around, and people lived the good life, full of culture and joy. This is part of the series Make History Fun Again, where the writers introduce
Spending time in nature boosts children’s academic achievement and healthy development, concludes a new analysis examining hundreds of studies. Ming Kuo, associate professor in the Department of Natural Resources and Environmental Sciences at the University of Illinois and lead author on the Frontiers in Psychology study, says she expected the critical review to lead to
Access to quality early childcare is without a doubt essential. Unfortunately, parents are facing a fairly significant care gap. According to a survey released by NPR along with the Robert Wood Johnson Foundation and the Harvard T.H. Chan School of Public Health, for every three families seeking early childcare nationwide, only one spot is available.
Oxygen deprivation associated with preterm birth leaves telltale signs on the brains of newborns in the form of alterations to cerebellar white matter at the cellular and the physiological levels. Now, an experimental model of this chronic hypoxia reveals that those cellular alterations have behavioral consequences. Chronic sublethal hypoxia is associated with locomotor miscoordination and
Each year, more than 6 million children in the United States are referred to Child Protective Services for abuse or neglect. Previous research on the consequences of early life stress and child maltreatment shows that these children will be more likely to develop a multitude of social and mental health problems. Teens and adults who
Glial cells surround neurons and provide support—not unlike hospital staff and nurses supporting doctors to keep operations running smoothly. These often-overlooked cells, which include oligodendrocytes and astrocytes, are the most abundant cell types in the central nervous system. But these cells do more than support neurons. They also actively influence them, University of California, Riverside,
Recently published research shows that learning disabilities (LD) diagnosed in childhood are associated with adult-age mental health problems, delays or difficulties in attaining an educational degree, and unemployment. In the longitudinal study conducted by the Niilo Mäki Institute and University of Jyväskylä Finland, individuals with childhood LD (n = 439) were compared to a population-based
Detecting patterns is an important part of how humans learn and make decisions. Now, researchers have seen what is happening in people’s brains as they first find patterns in information they are presented. Findings showed that the brain processes pattern learning in a different way from another common way that people learn, called probabilistic learning.
Say you are shown an apple, a banana and a fruit you have never seen before. Then you are asked to pick the “pifo.” Which fruit would you choose? Chances are you would select the novel fruit. Children often use the same strategy—leveraging their knowledge of familiar objects—to learn new words and connect them with
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