Increasingly, doctors are treating lung cancer based on the genetic rearrangements driving the disease. For example, cancers that are driven by changes in the genes ALK, EGFR, and ROS1 can now all be paired with drugs that target these specific changes. However, these cancers are not only dangerous in the lung where they appear, but
Breathing in additional oxygen improves the function of blood vessels in the brain of people with breathing difficulties caused by lung conditions, according to new research published in Experimental Physiology. These findings could have implications for future research aiming to prevent the development of diseases affecting the brain, such as dementia. Chronic obstructive pulmonary disease
A cancer treatment already approved for use in certain types of cancer has been found to block cell growth in a common form of lung cancer for which there is currently no specific treatment available. The new findings, published today in Science Translational Medicine and led by the University of Glasgow, suggest that a large
Reviewing medical information gathered on more than 6,000 adults over a 10-year period, Johns Hopkins researchers have found that lower than normal blood levels of vitamin D were linked to increased risk of early signs of interstitial lung disease (ILD). Interstitial lung disease is a relatively rare group of disorders characterized by lung scarring and
A test that analyzes free-floating DNA in the blood may be able to detect early-stage lung cancer, a preliminary report from the ongoing Circulating Cell-Free Genome Atlas (CCGA) study suggests. The findings, from one of the first studies to explore whether sequencing blood-borne DNA is a feasible approach to the early cancer detection, will be
How do you remove a magnet stuck in a 9-year-old girl’s lung? Doctors settled on the novel method of using a stronger magnet to slide it out! A girl in Mangalore, India, went to hospital with an inch-long magnet in her lung She had swallowed the small piece of metal while playing with her sister
A new anti-cancer drug may be effective against a wider range of cancers than previously thought. Using a mouse model and samples taken from cancer patients, a team from the Technical University of Munich (TUM) has shown that a new class of drugs known as SHP2 inhibitors is also effective against aggressive, hard-to-treat tumors such
A collaborative study between the American Cancer Society and the National Cancer Institute finds rates of lung cancer, historically higher among men than women, have flipped among whites and Hispanics born since the mid-1960s. The authors of the study, which appears in the New England Journal of Medicine, say future research is needed to identify
The number of cases of progressive massive fibrosis, the most severe form of black lung disease, has been increasing dramatically among coal workers and especially younger workers in central Appalachia. These new findings represent the first-ever documentation of this spike and were presented by Kirsten Almberg, research assistant professor of environmental and occupational health sciences
What does YOUR handshake reveal? Study finds a weaker grip is linked to an early death from cancer, lung disease, or a heart attack Scientists measured the grip strength of half a million people over three years They compared their grip with their health outcomes over time The weaker the grip, they found, the higher
Among organ transplant patients, those receiving new lungs face a higher rate of organ failure and death compared with people undergoing heart, kidney and liver transplants. One of the culprits is inflammation that damages the newly transplanted lung. Now, researchers at Washington University School of Medicine in St. Louis and Northwestern University Feinberg School of
Lung cancer is the second most prevalent form of cancer in men and women and the top cancer killer among both sexes. The American Cancer Society (ACS) estimate that in 2018, 154,050 people in the United States will have died from the disease. The World Health Organization (WHO) suggest that 1.69 million deaths are brought
A drug that failed to effectively strike larger targets in lung cancer hits a bulls-eye on the smaller target presented by a previously untreatable form of the disease, researchers at The University of Texas MD Anderson Cancer Center report in Nature Medicine. Their research provided the scientific underpinning for clinical trials under way of the
Every year, health care providers in the United States discover more than 1.6 million lung nodules in patients. Many are “incidentally detected,” meaning they are found during evaluation for an unrelated cause (for example, a chest X-ray after a fall). Although 75 to 85 percent of these incidentally detected nodules turn out to be benign,
Further evidence that immunotherapy provides long-term survival benefit for patients with lung cancer was presented today at ELCC 2018 (European Lung Cancer Congress) in Geneva, Switzerland. Researchers presented the three-year survival results of the randomised phase 2 POPLAR trial in second line, which is the longest follow-up reported to date with anti-programmed death ligand 1
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