A computer model developed by Cleveland Clinic oncologist Timothy Chan, MD, Ph.D., and colleagues accurately predicts whether immune checkpoint blockade (ICB) will be effective in patients diagnosed with a wide variety of cancers. The forecasting tool, developed using machine learning, assesses multiple biological and clinical variables in an individual patient’s condition to predict the degree
Analyzing the forces at work behind the obstructions that cause heart attacks is crucial for identifying patients at risk of these events, says a study published today in eLife. The findings suggest that bringing such biomechanical analyses into clinical practice could allow cardiologists to predict a future heart attack in patients by simulating the distribution
Reply to @gianna_2323 Before and after photos. Lmk what you think! #foreheadreduction #beforeandafter #plasticsurgery ♬ original sound – Camilla Source: Read Full Article
A research team led by the Icahn School of Medicine at Mount Sinai (Icahn Mount Sinai) has built the first cellular model to depict the evolution of acute myeloid leukemia (AML), from its early to late stages. By using gene editing technologies to alter genes that make cells malignant, the team was able to identify
When Amber Jean Rowan was diagnosed with alopecia, an autoimmune disease in which the body attacks its own hair follicles and causes hair loss, 13 years ago, she developed an understandable thirst for knowledge on the subject. She went to medical professionals regarding possible treatments, of course, but despite a thriving internet, the more nuanced
Celeb Moms Share Breastfeeding Pictures Mom power! Check out these A-list mothers including Gisele Bundchen, Miranda Kerr, and Jaime King, who proudly show off their breast-feeding skills—and their adorable babies, too. In order to view the gallery, please allow Manage Cookies For access to all our exclusive celebrity videos and interviews – Subscribe on YouTube! Source:
Highmark Health, in collaboration with Google Cloud, today announced its Living Health model and corresponding platform that aims to reshape how healthcare is delivered to be a more coordinated, personalized and technology-enabled experience. Throughout the companies’ six-year strategic partnership, Highmark will support its Living Health model through the development of the Living Health Dynamic Platform,
University of California, Irvine health sciences researchers have created a machine-learning model to predict the probability that a COVID-19 patient will need a ventilator or ICU care. The tool is free and available online for any healthcare organization to use. “The goal is to give an earlier alert to clinicians to identify patients who may
A form of artificial intelligence designed to interpret a combination of retinal images was able to successfully identify a group of patients who were known to have Alzheimer’s disease, suggesting the approach could one day be used as a predictive tool, according to an interdisciplinary study from Duke University. The novel computer software looks at
Sometimes, too much of a good thing can turn out to be bad. This is certainly the case for the excessive cell growth found in cancer. But when cancers try to grow too fast, this excessive speed can cause a type of cellular aging that actually results in arrested growth. Scientists at Duke-NUS Medical School
Even before the pandemic and the presidential election, Americans reported some of the highest perceived levels of stress in the world, according to the American Psychological Association. Not only does stress have negative effects on work and personal relationships, it also increases the risk of many chronic conditions, such as heart disease and Alzheimer’s disease,
A sophisticated type of artificial intelligence (AI) called deep learning can help rapidly detect blockages in the arteries that supply blood to the head, potentially speeding the onset of life-saving treatment, according to a study published in Radiology. Large vessel occlusions are blockages in the arteries that supply oxygenated blood to the brain. These occlusions
A team of researchers has been modeling the potential spread of the coronavirus pandemic in Italy. Using their model, they can calculate the number of exposed and highly infectious individuals and the daily isolation efforts required to bring down the epidemic curve. In April, a team led by Professor Andrea Rinaldo, the head of EPFL’s
Michigan State University researchers have created for the first time a miniature human heart model in the laboratory, complete with all primary heart cell types and a functioning structure of chambers and vascular tissue. In the United States, heart disease is the No. 1 cause of death. “These minihearts constitute incredibly powerful models in which
A team of Brown University researchers has developed a new computer model that simulates the way red blood cells become misshapen by sickle cell disease. The model, described in a paper published in Science Advances, could be useful in the preclinical evaluation of drugs aimed at preventing the sickling process. “There are currently only two
Increasing the levels of the anti-aging protein hormone Klotho improves the neurological deficits and prolongs life span in an experimental model with Amyotrophic Lateral Sclerosis (ALS). In addition, brain immune cells called microglia play an important role in protecting the brain against inflammation and, likely, motor neuron loss in this model. ALS or Lou Gehrig’s
Incorporating genetic diversity into a mouse model of Alzheimer’s disease resulted in greater overlap with the genetic, molecular and clinical features of this pervasive human disease, according to a study funded by the National Institute on Aging (NIA), part of the National Institutes of Health. The study also suggests that adding genetic diversity may be
Children with autism often find social interactions awkward, leaving them isolated. Now in a study appearing in ACS’ Journal of Medicinal Chemistry, scientists report that they have discovered a first-of-its-kind compound that promotes social interaction among laboratory mice that display autistic traits. The finding could lead to the development of drugs capable of improving social
MONDAY, Sept. 17, 2018 — For patients with advanced heart failure who are listed for transplantation, mortality risk is related to adverse events and end-organ dysfunction that vary over time, according to a study published in the Aug. 7 issue of the Journal of the American College of Cardiology. Eugene H. Blackstone, M.D., from the
A heart attack triggers an acute inflammatory response, followed by resolution of inflammation and wound healing. A severe heart attack, however, can cause chronic and sustained inflammation that leads to heart failure and death. In mouse experiments, University of Alabama at Birmingham scientists now have shown a way to hit an immunological “reset button” that
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