Over the last decade, neurobiology has been focused on the functioning of neural networks rather than single nerve cells. It is at this level that the key functions of the brain are performed, including processing, storage and transmission of information. However, researchers are facing some methodological difficulties in the investigation of neural networks. Traditional methods
The waste-management system of the cell appears to play an important role in the spread of Alzheimer’s disease in the brain. A new study has focused on small, membrane-covered droplets known as exosomes. It was long believed that the main task of exosomes was to rid the cell of waste products. However, the understanding of
It’s the critical first step in treating everything from strokes to cancer: a timely and accurate diagnosis. Today, doctors often rely on biomarkers, such as cardiac troponin, the protein that appears in the blood after a heart attack, to help them figure out what’s going on with patients. But the information the biomarkers provide can
Cells have traditionally been categorized into different types, such as T-cells and B-cells, based on observable features. But new research published in Nature Communications shows cells are far more complex. Purdue University researchers created an algorithm called ACTION to group cells based on their primary function and pinpoint the genes responsible for those functions. They
A new study of the educational needs of students who are native users of American Sign Language (ASL) shows glaring disparities in their treatment by the U.S Department of Education. The article, “If you use ASL, should you study ESL? Limitations of a modality-b(i)ased policy”, by Elena Koulidobrova (Central Connecticut State University), Marlon Kunze (Gallaudet
A first look at the new European Guidelines for the treatment of high blood pressure was presented at the European Society of Hypertension meeting in Barcelona on June 9th 2018. These long-awaited guidelines have been jointly developed by clinicians representing the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH). The guidelines
Incredible footage by Hollywood director captures top New York surgeon implanting a mechanical heart for star-studded movie about US doctor who saved a Dominican sex worker’s life WARNING: GRAPHIC CONTENT A new movie, Corazon, tells the true story of Dr Mario Garcia at Montefiore saving the life of a young Dominican woman, Elena Ramirez The
Congo’s health ministry says another Ebola case has been confirmed as the pace of new cases slows one month after the outbreak was officially declared. There are now 38 confirmed cases of the virus, including 13 deaths, the health ministry said late Thursday. The newest confirmed case is in rural Iboko and is linked to
Researchers from Queen Mary University of London have developed new cell-based technologies which could help improve understanding of the muscle-wasting disease Duchenne muscular dystrophy (DMD) and test potential drugs for the disease. DMD is a genetic disorder causing muscle degeneration and weakness, caused by an absence of the protein dystrophin. DMD usually affects only boys,
Immunotherapy is a form of cancer therapy that boosts the body’s immune system in the fight against tumors. Adoptive cell transfer (ACT), in particular, is a type of immunotherapy that strengthens a specific kind of immune cell: T cells. In ACT, healthcare professionals collect T cells from the malignant tumor and isolate immune cells that
Adele has been hailed as "an artist who comes around once every generation". She is a vocal force whose emotional ballads are masterpieces composed of powerful belts and airy falsettos. For many, it may be hard to imagine that the Grammy Award-winning singer would have trouble nailing any song, especially one of her own. But
Women are more prone to the development of autoimmune diseases. The female hormone estrogen is likely to affect the immune system. A team of scientists from Turku Center for Biotechnology and University of Georgia reported new findings related to the involvement of estrogen hormone receptor in autoimmune diseases. The incidence of autoimmune diseases such as
The winds of change are blowing through Chile where a youthful sexual revolution is shattering taboos—but also sparking an explosion of HIV cases that has set off alarm bells in the traditionally conservative Latin American country. Chile has the highest rate of HIV cases in the region—some 5,816 new cases were registered last year, a
Less fatigue and better recovery of cognitive abilities such as learning and memory. These may be the results of growth hormone treatment after a stroke, an experimental study of mice published in the journal Stroke suggests. “We hope that this work can pave the way for clinical studies involving the use of human growth hormone
Getting a new pharmaceutical from an idea in the chemistry lab to market takes many years and billions of dollars. Each year just several dozen new drugs are approved for use in the United States. Human “organs-on-chips” are leading a revolution in drug safety testing. These devices use human cells to model the structure and
A new anti-cancer drug may be effective against a wider range of cancers than previously thought. Using a mouse model and samples taken from cancer patients, a team from the Technical University of Munich (TUM) has shown that a new class of drugs known as SHP2 inhibitors is also effective against aggressive, hard-to-treat tumors such
Eating a handful of nuts 3 times a week can reduce the risk of developing an irregular heartbeat – a major cause of stroke – by 18%, study finds Study looked at 60,000 Swedish adults and their heart health over 17 years Nearly 1.3 million Britons suffer from irregular heartbeat Nut consumption was also associated
The case for permethrin-treated clothing to prevent tick bites keeps getting stronger. In a series of experiments conducted by researchers at the U.S. Centers for Disease Control and Prevention, clothing treated with an insecticide known as permethrin had strong toxic effects on three primary species of ticks known to spread disease-causing pathogens in the United
Combining data from electronic health records with results from standardized depression questionnaires better predicts suicide risk in the 90 days following either mental health specialty or primary care outpatient visits, reports a team from the Mental Health Research Network, led by Kaiser Permanente research scientists. The study, “Predicting Suicide Attempts and Suicide Death Following Outpatient
In a recent study published in the Journal of Clinical Investigation, Mayo Clinic researchers identified that an FDA drug approved for myelodysplastic syndrome may be useful to treat triple-negative breast cancer, which is one of the most aggressive and lethal types of breast cancer. In this study, Mayo investigators identified that the drug 5-aza-2′-deoxycytidine (decitabine)
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