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Researchers investigating a key signaling protein in Huntington’s disease describe deleterious effects on heart function, going beyond the disease’s devastating neurological impact. By adjusting protein levels affecting an important biological pathway, the researchers improved heart function in experimental animals, shedding light on the biology of this fatal disease. “Heart disease is the second leading cause

Farmers worldwide face mounting pressure to increase agricultural yields to keep up with human population growth. Consequently, chemical use is on the rise – in many cases a cocktail of chemicals, from fertilizers to herbicides to insecticides. But in countries where human population growth is highest, including China, South East Asia and South America, these

People who are 30 pounds or more overweight may want to slim down a bit even if they don’t have high blood pressure or any other heart disease risk, according to scientists at Wake Forest Baptist Medical Center. In a study published in the May issue of the Journal of the American College of Cardiology,

Women who’ve previously experienced a heart attack have twice the risk of later myocardial ischemia provoked by mental stress when compared to men with a similar history, according to a study published in Circulation. Hawkins Gay, MD, MPH, a third-year resident in internal medicine, was a co-author of the study, which sampled 418 individuals and

After surgery for breast cancer women who have undergone breast reconstruction using abdominal tissue do not have a higher risk of recurrence than women who do not undergo breast reconstruction. This has been shown by researchers at Karolinska Institutet in a study published in the British Journal of Surgery. In Sweden today, more than 90,000

Six in seven women with a family history of breast cancer opt out of taking tamoxifen as a preventative measure, according to a study funded by Cancer Research UK and published in Breast Cancer Research and Treatment today. Researchers asked 258 healthy women across England who had been identified as having an increased risk of

A recent study from researchers at the Icahn School of Medicine at Mount Sinai provides new insights into a link between inflammatory bowel disease (IBD) and Parkinson’s disease, and may have significant implications for the treatment and prevention of Parkinson’s disease. The recent study, published in JAMA Neurology, shows that individuals with IBD are at

Cellulitis treated with a six-day course of intravenous antibiotic flucloxacillin resulted in greater rates of relapse at 90 days post treatment despite having similar short-term results to the 12-day course, according to research presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). Cellulitis, a skin infection that can become life threatening,

As an undergraduate student at York University, Joel Lopata was studying film production and jazz performance when a discrepancy became apparent. “I noticed students in the jazz program were really developing a language of creative engagement, whereas in the film program, we weren’t having the same education. It was a lot more theoretical than practical,

Measles still claims young lives in Romania, where nearly 40 children have died in an outbreak that many blame on parents being misled by scare stories that vaccinating them is dangerous. Some 12,000 people have contracted measles since late 2016 in the European Union’s second-poorest country, 46 of them died. Among the dead, 39 were

People with obesity are more likely to develop a rapid and irregular heart rate, called atrial fibrillation, which can lead to stroke, heart failure and other complications, according to Penn State researchers. Researchers followed a large group of participants, equally divided between people with obesity and without, for eight years. They found that people with

The standard of care for kidney cancer patients continues to improve. The U.S. Food and Drug Administration granted approval to the combination of two immunotherapy drugs, ipilimumab and nivolumab, for the treatment of metastatic kidney cancer. The results of the large, international clinical trial leading to the approval were just published the prestigious New England

One class of drug used to treat type 2 diabetes may not reduce the risk of death when compared with placebo, suggests new findings. The research, led by scientists from Imperial College London and published in the Journal of the American Medical Association, studied three types of diabetes treatment: sodium-glucose cotransporter 2 (SGLT-2) inhibitors, glucagon-like

Following a heart attack, the parts of the heart muscle that die do not regenerate into new heart tissue and instead are replaced by scar tissue. Using rodent models, researchers at Baylor College of Medicine are looking for a means to genetically convert this scar tissue into muscle tissue at the cellular level, which could

Researchers at Karolinska Institutet in Sweden have developed a new disease model for neurodegenerative diseases such as ALS and MS that can be used to develop new immunotherapies. The model is described in a publication in the scientific journal Nature Immunology. All of the body’s organs contain macrophages, which, as part of the immune system,

The high estrogen levels that typically afford younger women protection from cardiovascular disease appear to instead multiply their risk if they have type 1 diabetes, researchers say. A new study is examining the blood vessel health of these women during normal estrogen peaks and valleys and seeing whether treatment with over-the-counter supplements can help restore

Rising income and the subsequent improved standards of living have long been thought to be the most important factors contributing to a long and healthy life. However, new research from Wolfgang Lutz and Endale Kebede, from IIASA and the Vienna University of Economics and Business (WU) has shown that instead, the level of education a

For decades, the neuroscience community has been baffled by the existence of dense connections in the brain that seem to be going “backwards.” These connections, which span extensively across distant areas of the neocortex, are clearly conveying important information. But until now, the organization of the connections, and therefore their possible role, was largely unknown.

Patients with advanced prostate cancer who received more intensive treatment experienced worse quality of life three months after treatment, but a better quality of life in the long term, compared to those on standard therapy, according to a new Northwestern Medicine study. The findings were published in the Journal of Clinical Oncology. “Treatment of prostate

The hippocampus is an area of the brain commonly linked with memory and dementia. But new U of T Scarborough research finds that it may also yield important clues about a range of mental health illnesses including addiction, anxiety and depression. The research, authored by a team of neuroscientists, found that a specific part of