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Patients with hepatocellular carcinoma (HCC) waiting for a liver transplant in the USA are now significantly less likely to receive a new liver than they were around a decade ago. A nationwide study presented today at The International Liver Congress 2018 in Paris, France, has confirmed that patients with HCC on the liver transplant list

Melanoma, a relatively rare but deadly skin cancer, has been shown to switch differentiation states—that is, to regress to an earlier stage of development—which can lead it to become resistant to treatment. Now, UCLA researchers have found that melanomas can be divided into four distinct subtypes according to their stages of differentiation. Cell subtypes that

Two common iron compounds increase the formation of a known biomarker for cancer, according to a new study of cancer cells from Chalmers University of Technology, Sweden. The two compounds, ferric citrate and ferric EDTA, are often used in dietary supplements and as a food additive respectively, in worldwide markets including the U.S. and the

A new study shows that more frequent and severe menopausal symptoms such as hot flashes, sleep disturbance, loss of sexual interest, weight gain and other quality of life measures, were associated with markers of vascular aging, according to researchers at the University of Colorado Anschutz Medical Campus. The researchers, however, found no association between these

(HealthDay)—For older adults, dipeptidyl peptidase 4 inhibitors (DPP-4Is) are not associated with increased risk of acute pancreatitis, according to a study published online April 4 in Diabetes Care. Jin-Liern Hong, Ph.D., from the University of North Carolina at Chapel Hill, and colleagues examined the risks of acute pancreatitis among U.S. Medicare beneficiaries, aged 66+ years,

Adding the monoclonal antibody drug trastuzumab—already used to treat certain breast cancers—to the chemotherapy regimen of women with a rare form of uterine cancer lengthens the amount of time their tumors are kept from growing, according to Johns Hopkins Medicine researchers conducting a small phase II trial of the regimen, testing its safety and value.

On-site testing of ‘party drug’ pills could reduce the harms caused by drug use and potentially save lives, according to an independent review of Australia’s National Drug Strategy, published in the open access Harm Reduction Journal. Dr Andrew Groves at Deakin University, Australia, examines evidence in support of pill testing to reduce fatalities caused by

People living near oil and gas facilities along Colorado’s Northern Front Range may be exposed to hazardous air pollutants, including carcinogens like benzene, that could pose health risks above levels deemed acceptable by the U.S. Environmental Protection Agency, according to researchers at the Colorado School of Public Health, Boulder County Public Health, CU Boulder, the

In January of 2018, 15 Kentucky Medicaid beneficiaries filed a lawsuit in the United States District Court for the District of Columbia challenging the federal government’s legal authority to launch Medicaid work demonstrations and its approval of Kentucky’s Medicaid work demonstration, the first in the nation. The lawsuit (Stewart v. Azar) seeks to block the

A team of researchers from the U.S., China and Korea has developed a small, skin-like sensor that can be attached to a human patient to collect temperature and pressure information and wirelessly send it to healthcare workers. In their paper published in the journal Science Translational Medicine, the group describes the sensor, how it works

In collaboration with a number of American colleagues, researchers from Uppsala University have found an Achilles’ heel for the most common form of malignant child brain tumours. By combining two kinds of medicines, it is possible to simultaneously attack the cancer cell’s division and its reinforcement system, which is necessary in order for treatment to

San Diego’s Dexcom has won regulatory approval for its latest continuous glucose monitoring system that eliminates the need for finger pricks and is nearly one-third smaller than its current wearable sensor for diabetes patients. The Food and Drug Administration this week gave the green light to Dexcom’s G6 system for delivering real time blood sugar

Alcohol can make a person engrossed in an activity oblivious to what’s going on around them, no matter how bizarre or unexpected that might be. New research led by the University of Portsmouth supports the alcohol myopia theory – that alcohol reduces a person’s ability to notice more than what’s right in front of them.

In autoimmune diseases such as type 1 diabetes, some of the immune system’s T cells mistakenly attack the body’s own cells, while protective T regulatory cells try to defend against that attack. Scientists at Joslin Diabetes Center have shown in a mouse model of type 1 diabetes that animals with fewer of a poorly studied

Elderly Australian women who ate more vegetables showed less carotid artery wall thickness, according to new research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association. Cruciferous vegetables including broccoli, cauliflower, cabbage and Brussels sprouts proved the most beneficial. “This is one of only a few

There are many factors that determine your likelihood of developing cancer, including age, genetic predisposition and lifestyle. Some factors, like age, cannot be controlled, so experts recommend learning as much as possible about your family’s medical history and doing everything you can to live a healthy lifestyle. “Sometimes our environment may not be within our

(HealthDay)—Outcomes-based pricing does not reduce the costs of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, according to a research letter published online April 3 in the Annals of Internal Medicine. Dhruv S. Kazi, M.D., from the University of California in San Francisco, and colleagues examined the effect of outcomes-based pricing on the cost-effectiveness of PCSK9

Massachusetts Eye and Ear researchers have shown that mifepristone, a drug currently FDA-approved for chemical abortion, prevents the growth of vestibular schwannoma (also known as acoustic neuroma) cells. This sometimes-lethal intracranial tumor typically causes hearing loss and tinnitus. The findings, published online today in Scientific Reports, suggest that mifepristone is a promising drug candidate to

A jolt of the unexpected can have far-reaching effects, according to new research from a University of Illinois expert who studies leadership and creativity. Surprises are memorable, able to garner attention and arouse emotion, but a less heralded effect is that they can serve to shift attitudes and provide an avenue to influence people, said

The World Health Organization (WHO) recommends the introduction of typhoid conjugate vaccine (TCV) for infants and children over six months of age in typhoid-endemic countries. This new policy will help ensure access to typhoid vaccination in communities most impacted by the disease, which is responsible for nearly 12 million infections and between 128,000 and 161,000