Tag: target

A new study led by researchers at Washington State University has identified a protein that could be the key to improving treatment outcomes after a heart attack. Published in the Journal of Biological Chemistry, the research suggests that protein kinase A (PKA) plays a role in heart muscle cell necrosis, a major type of cell

By now we’ve learned that if a food item is trending on TikTok, it’s probably going to find its way into our cabinets soon enough. We’ve already discovered so many incredible products on the social media app that we love using in our everyday life — remember life without whipped coffee?! So when we noticed

By now we’ve learned that if a food item is trending on TikTok, it’s probably going to find its way into our cabinets soon enough. We’ve already discovered so many incredible products on the social media app that we love using in our everyday life — remember life without whipped coffee?! So when we noticed

An abdominal aortic aneurysm (AAA) is a bulging of the aorta, the body’s main blood vessel, which runs from the heart down through the chest and stomach. Prevalence of AAA in the population is high, up to nearly 13% depending on age group, particularly for men aged 65 and over. An AAA can get bigger

Easter is in mere weeks, and we’re already dusting off our Easter decor (and purchasing a few new items), planning our Easter spread, and purchasing all the essentials to curate the perfect Easter egg basket for the kids — and that includes Easter treats and candies. Related story Target Is Selling a Bunny-Shaped Peeps Pancake

U.S. President Joe Biden delivers remarks as he takes part in a Munich Security Conference virtual event from the East Room at the White House in Washington, U.S., February 19, 2021. REUTERS/Kevin LamarquePORTAGE, Mich. (Reuters) – President Joe Biden on Friday said he is confident the United States will exceed his goal of delivering 100

Biomedical engineers at Duke University have discovered a pharmaceutical target that, when activated, can reverse bone degradation caused by osteoporosis in mouse models of the disease. “The most widely used drugs currently approved by the FDA to treat osteoporosis can prevent further bone loss, but they don’t help rebuild the bone,” said Shyni Varghese, professor

Researchers in New York have found that treating human prostate cancer cells with a drug that targets a protein called PHLPP2 may prevent the cancer cells from spreading to other organs in the body. The study, which will be published May 15 in the Journal of Cell Biology, reveals that inhibiting PHLPP2 lowered the levels

Target is our go-to spot for all things summer, whether we’re looking for a new bathing suit, patio furniture, or sunscreen. But now, they’re even more essential to our summer shopping routine, because this year, Target will be selling a $5 bottle of sangria, part of their California Roots wine collection. California Roots is basically

Researchers have identified a biomarker and a possible new therapy for melanoma. Microphthalmia-associated transcription factor (MITF) is a protein that plays a pivotal role in the maintenance of the melanocyte (cells that make melanin) lineage, differentiation of normal and malignant melanocytes and the survival of melanoma cells. “We have now detected the first useful chemical

Understanding and mitigating the role of epigenetics (environmental influences that trigger changes in gene expression) in disease development is a major goal of researchers. Now, a newly published paper featured on the March cover of the journal Brain adds significantly to this work by detailing how metabolites can be used to inhibit epigenetic mechanisms and

Differential H3K27AC marks were identified at enhancer regions of genes including c-MYC, MED1, OCT-4, NANOG, and SOX2 that can act as super-enhancers (SE), cluster of genes in non-cancerous, cancerous and metastatic PDAC cell lines. GZ17-6.02 affects acetylation of the genes, reduces transcription of major transcription factors, sonic hedgehog pathway proteins, and stem cell markers. Dr.

In an article published online by Frontiers in Endocrinology, researchers at the Medical University of South Carolina (MUSC) report that they have identified a potential therapeutic target for lung fibrosis or scarring. They showed in a preclinical model that the protein promotes fibrosis by turning on profibrotic genes and increasing levels of profibrotic factors, including

Researchers have found an effective target in the brain for electrical stimulation to improve mood in people suffering from depression. As reported in the journal Current Biology on November 29, stimulation of a brain region called the lateral orbitofrontal cortex (OFC) reliably produced acute improvement in mood in patients who suffered from depression at the

A cytokine signature found in certain kinds of breast cancer cells can not only serve as a diagnostic tool for HER2-negative cancers but also offer an effective treatment target. A research team led by Karolina Palucka, M.D., Ph.D., a professor at The Jackson Laboratory (JAX), has collaborated with researchers at The Baylor Institute for Immunology

The only thing better than finding a product that you love is when it becomes even more accessible. For fans of E.L.F. 's best-selling Beauty Shield Magnetic Mask Kit, today is your lucky day. While you could only previously find the mask in E.L.F.'s online shop and Target stores, you can now scoop up a

Do you know someone afflicted with Alzheimer’s disease? Odds are the answer to that question is yes, since Alzheimer’s is one of the most common age-related disorders in the United States. It’s also the fifth-leading cause of death among adults aged 65 and older. But as pervasive as the disease may be, one of its

Flower water hydrosols are gaining traction in the natural skin-care market. But, according to Adina Grigore, founder of S.W. Basics, most of the products being marketed as hydrosols are waters that are merely scented with additives. A core principle of S.W. Basics, which Grigore launched in 2011, is to make products with five ingredients or

Chikungunya virus is a growing threat to the United States and other regions of the world as the mosquito that carries the virus expands its reach. Telltale symptoms of chikungunya infection are fever and joint pain that last about a week. But in up to half of patients, the virus can cause a debilitating form

The discovery of a new mechanism involved in depression – and a way to target it with a drug as effective as classical antidepressants—provides new understanding of this illness and could pave the way for treatments with fewer side effects. In a study published in Nature Medicine, a team of scientists at McGill University and