For the first time, researchers at the University of Gothenburg have shown that metastases in patients with malignant melanoma gain access to the circulatory system not only through the outgrowth of new blood vessel branches, but also an alternative process in which one blood vessel divides into two parallel vessels by longitudinal splitting. The finding
Adding to the growing body of literature demonstrating the feasibility of correcting lethal genetic diseases before birth, researchers at Children’s Hospital of Philadelphia (CHOP) have used DNA base editing in a prenatal mouse model to correct a lysosomal storage disease known as Hurler syndrome. Using an adenine base editor delivered in an adeno-associated viral vector,
Volunteer surgeons and students take part every year in medical-surgical mission Medipinas, to perform free operations for patients with no resources in the Santa Maria Josefa Hospital Foundation of Iriga City, in the Philippines. In order to improve the monitoring of operations and to prevent infections in the surgical wounds of these patients, the Medipinas
Summer weather is upon us, and that means beach days, pool parties, and barbeques among plenty of other outdoor activities. We all know that if we plan to spend more than fifteen minutes outdoors, we need to wear a good sunscreen on our faces and bodies (via Harvard Health), but if we’re honest, life sometimes gets in
The use of ‘ice’ flavored e-cigarettes may be common and positively associated with conventional smoking and nicotine dependence among young adults, suggests research published online in the journal Tobacco Control. And it’s unclear where these’ hybrid’ vapes, combining fruit/sweet and cooling flavors, fit into current or future regulatory frameworks, which apply restrictions according to distinct
Dr. Jay Avasarala, professor of neurology and director of the University of Kentucky’s Multiple Sclerosis Clinic, and co-authors, conducted a retrospective study in which they evaluated approximately 96.5 million enrollees in a database. More than 200,000 of the enrollees had inflammatory bowel disease (IBD). The research focused on looking at the effect of TNF-alpha inhibitors,
Uncontrolled bleeding continues to be one of the most common causes of preventable death from a traumatic injury. However, patient survival from such injuries has improved in Los Angeles County due to an increased use of tourniquets to help stop severe bleeding before a patient arrives at a hospital. Findings appear in a Journal of
A technique called percutaneous peripheral nerve stimulation yields “impressive” reductions in pain scores and opioid use during the first week after common orthopedic surgery procedures, concludes a randomized clinical trial published Online First in Anesthesiology, the official peer-reviewed journal of the American Society of Anesthesiologists (ASA), today. The benefits of postoperative nerve stimulation were “much
When you think of ways to treat opioid use disorder, you might think methadone clinics and Narcotics Anonymous meetings. You probably don’t imagine stretches and strengthening exercises. But Anne Swisher—professor at the West Virginia University School of Medicine—is working to address opioid misuse in an unconventional way: through physical therapy. She and her colleagues have
The World Health Organization said Wednesday that ivermectin—touted by some on social media as a COVID-19 “miracle cure”—should not be used to treat coronavirus patients. In response to the swirl of claims around the cheap anti-parasite drug, the WHO issued guidelines saying ivermectin should only be used on COVID-19 patients in clinical trial settings. The
The World Health Organization said Wednesday that ivermectin—touted by some on social media as a COVID-19 “miracle cure”—should not be used to treat coronavirus patients. In response to the swirl of claims around the cheap anti-parasite drug, the WHO issued guidelines saying ivermectin should only be used on COVID-19 patients in clinical trial settings. The
Scientists at the Proteomics Core Unit of the Spanish National Cancer Research Centre (CNIO), headed by Javier Muñoz, have described the mechanisms, unknown to date, involved in maintaining embryonic stem cells in the best possible state for their use in regenerative medicine. Their results, published in Nature Communications, will help to find novel stem-cell therapies
Hong Kong suspended use of the Pfizer vaccine Wednesday after its Chinese distributor informed the city that one batch had defective bottle lids. The city’s government said the suspension was immediate while the matter is investigated by distributor Fosun Pharma and BioNTech, the German company which created the vaccine with American pharmaceutical firm Pfizer. BioNTech
Tobacco smoke-exposed children utilize emergency and urgent care services more often than unexposed children, which contributes to a large toll on the nation’s health care system, says research led by the University of Cincinnati. The study, recently published in the journal PLOS ONE, concluded: Children who are exposed to tobacco smoke have higher pediatric emergency
Machine learning can be used to comb through online reviews of substance use treatment facilities to home in on qualities that are important to patients but remain hard to capture via formal means, such as surveys, researchers from the Perelman School of Medicine at the University of Pennsylvania show. The researchers found that professionalism and
Germany, France and Italy on Monday became the latest countries to suspend use of AstraZeneca’s COVID-19 vaccine over reports of dangerous blood clots in some recipients, though the company and European regulators have said there is no evidence the shot is to blame. AstraZeneca’s formula is just one of three vaccines in use on the
An independent analysis of the medical trials which formed the final basis of approval by the US Food and Drug Administration (FDA) strongly suggests the drug bremelanotide has very limited effectiveness as a treatment for hypoactive sexual desire disorder (HSDD) in women, and that trial participants preferred a placebo. The analysis, published today in the
If your fitness routine has moved mainly to your living room or bedroom, you’re probably after fitness kit that is compact and easy to use. Resistance bands have boomed in popularity during lockdown for this very reason. They take up basically zero space, and they add resistance and difficulty to simple moves – without the
At the time of writing, coronavirus disease 2019 (COVID-19) is seriously threatening human lives and health throughout the world. Before effective vaccines and specific drugs are developed, non-pharmacological interventions and numerical model predictions are essential. To this end, a group led by Professor Jianping Huang from Lanzhou University, China, developed the Global Prediction System of
Thousands of Britons are risking blindness because they do not use their eye drops properly, warn experts It is essential to apply pressure to inner corner of eye when squirting in liquid Otherwise the medication could drain out of the eye, rendering it ineffective But experts say specialists are failing to relay this, causing patients
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